Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)

for ARB

Sites in Los Angeles +3 more locations

Sponsor: Opus Genetics, Inc

Sex: All·Age: 18+

Code: NCT07185256·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

for Multiple Myeloma

Sites in San Francisco +8 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06500884·Phase 2·Recruiting·Listed Jul 2024

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Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System

for Chronic Heart Failure

Sites in San Francisco, La Jolla +6 more locations

Sponsor: AquaPass Medical Ltd.

Sex: All·Age: 21 - 79

Code: NCT06360380·Recruiting·Listed Apr 2024

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ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

for Hepatoblastoma

Sites in Los Angeles, San Francisco +2 more locations

Sponsor: Eureka Therapeutics Inc.

Sex: All·Age: 1 - 21

Code: NCT04634357·Phase 1, Phase 2·Recruiting·Listed Nov 2020

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

for Hemophilia A

Drug: NXT007

Sites in Sacramento +2 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 2 - 59

Code: NCT05987449·Phase 1, Phase 2·Recruiting·Listed Aug 2023

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DFT383 in Pediatric Participants With Nephropathic Cystinosis

for Nephropathic Cystinosis

Sites in San Diego, Stanford +2 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 5

Code: NCT06910813·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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Inappropriate Sinus Tachycardia Registry

for Inappropriate Sinus Tachycardia

Sites in Palo Alto, Redwood City +7 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: All ages

Code: NCT05107635·Recruiting·Listed Nov 2021

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ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

for X-linked Retinoschisis

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Atsena Therapeutics Inc.

Sex: All·Age: 6+

Code: NCT05878860·Phase 3·Recruiting·Listed May 2023

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NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

for Schizophrenia

Drug: NBI-1117568

Sites in Riverside, Garden Grove +3 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 65

Code: NCT07105098·Phase 3·Recruiting·Listed Aug 2025

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A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

for Healthy Participants

Sites in Los Angeles +7 more locations

Sponsor: Equilibra Bioscience LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06349473·Phase 1·Recruiting·Listed Apr 2024

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Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

for Sickle Cell Disease

Sites in Los Angeles, Palo Alto +4 more locations

Sponsor: Kamau Therapeutics

Sex: All·Age: 12 - 50

Code: NCT04819841·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

for Ventricular Ejection Fraction

Sites in Orange, Pasadena +6 more locations

Sponsor: Peerbridge Health, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06699056·Recruiting·Listed Nov 2024

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Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

for Refractory Metastatic Colorectal Cancer

Sites in Duarte, Santa Monica +4 more locations

Sponsor: Delcath Systems Inc.

Sex: All·Age: 18+

Code: NCT06607458·Phase 2·Recruiting·Listed Sep 2024

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Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sites in San Francisco, Stanford +7 more locations

Sponsor: Sonoma Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT06201416·Phase 1·Recruiting·Listed Jan 2024

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VIrtual STudy in Achondroplasia for the US (VISTA)

for Achondroplasia

Sites in San Francisco, Oakland +6 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 0 Months - 18

Code: NCT06168201·Recruiting·Listed Dec 2023

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A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

for Friedreich Ataxia

Sites in Los Angeles +6 more locations

Sponsor: Biogen

Sex: All·Age: 2 - 15

Code: NCT06953583·Phase 3·Recruiting·Listed May 2025

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Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Sites in Orange +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06704269·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair

for Peripheral Nerve Injuries

Sites in San Francisco, San Diego +6 more locations

Sponsor: Auxilium Biotechnologies

Sex: All·Age: 18 - 80

Code: NCT06529835·Recruiting·Listed Jul 2024

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A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

for Esophageal Squamous Cell Carcinoma

Sites in Los Angeles +3 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT05319730·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Sacramento +7 more locations

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06352359·Phase 1·Recruiting·Listed Apr 2024

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Use of CereGate Therapy for Freezing of Gait in PD

for Parkinson Disease

Sites in Redwood City +6 more locations

Sponsor: CereGate Inc.

Sex: All·Age: 21 - 80

Code: NCT05292794·Recruiting·Listed Mar 2022

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Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)

for Ileal Pouch

Sites in Los Angeles +7 more locations

Sponsor: Exegi Pharma, LLC

Sex: All·Age: 18+

Code: NCT05938465·Phase 1, Phase 2·Recruiting·Listed Jul 2023

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A Study to Assess Anktiva in Patients With Long Covid-19.

for Long COVID

1 location in San Francisco

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 70

Code: NCT07108036·Phase 2·Recruiting·Listed Aug 2025

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A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.

for Periodontitis (Stage 3)

Sites in Fullerton +8 more locations

Sponsor: McGuire Institute

Sex: All·Age: 30 - 75

Code: NCT06914596·Recruiting·Listed Apr 2025

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Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

for Leber Congenital Amaurosis 10

Sites in San Francisco +4 more locations

Sponsor: Laboratoires Thea

Sex: All·Age: 6+

Code: NCT06891443·Phase 3·Recruiting·Listed Mar 2025

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Dazucorilant in Patients With Amyotrophic Lateral Sclerosis

for Amyotrophic Lateral Sclerosis

Sites in San Francisco +3 more locations

Sponsor: Corcept Therapeutics

Sex: All·Age: 18+

Code: NCT05407324·Phase 2·Recruiting·Listed Jun 2022

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A Study of MGC028 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in San Francisco +6 more locations

Sponsor: MacroGenics

Sex: All·Age: 18+

Code: NCT06723236·Phase 1·Recruiting·Listed Dec 2024

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IKS014 in Advanced Solid Tumors That Express HER2

for Breast Cancer

Sites in Newport Beach +3 more locations

Sponsor: Iksuda Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT05872295·Phase 1·Recruiting·Listed May 2023

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A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

for Solid Tumours

Sites in Santa Monica, Beverly Hills +1 more location

Sponsor: Epkin

Sex: All·Age: 18+

Code: NCT06789172·Phase 1·Recruiting·Listed Jan 2025

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PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma

Sites in Newport Beach +5 more locations

Sponsor: PanTher Therapeutics

Sex: All·Age: 18+

Code: NCT06673017·Phase 1·Recruiting·Listed Nov 2024

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Transdermal Compress IDE Study

for Prosthesis and Implants

Sites in Sacramento +8 more locations

Sponsor: Balmoral Medical company

Sex: All·Age: 18 - 60

Code: NCT06134167·Recruiting·Listed Nov 2023

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An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

for Hematologic Malignancy

Drug: Pelabresib

Sites in Los Angeles +5 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06401356·Phase 3·Recruiting·Listed May 2024

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64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

for Prostatic Neoplasms, Castration-Resistant

Sites in Stanford +6 more locations

Sponsor: Clarity Pharmaceuticals Ltd

Sex: Male·Age: 18+

Code: NCT04868604·Phase 1, Phase 2·Recruiting·Listed May 2021

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Clinical Study of the inQB8 TTVR System (The MonarQ Study)

for Tricuspid Valve Regurgitation

Sites in Los Angeles, Thousand Oaks +4 more locations

Sponsor: inQB8 Medical Technologies, LLC

Sex: All·Age: 18+

Code: NCT06611579·Recruiting·Listed Sep 2024

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LYL273 for Patients With Relapsed or Refractory mCRC

for Colorectal Cancer

Sites in San Francisco, Duarte +2 more locations

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05319314·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes

for Obesity and Obesity-related Medical Conditions

1 location in Cypress

Sponsor: Pfizer

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06924320·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

for Cystic Fibrosis

Sites in Los Angeles +2 more locations

Sponsor: SpliSense Ltd.

Sex: All·Age: 18+

Code: NCT06429176·Phase 2·Recruiting·Listed May 2024

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A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease

for Danon Disease

Sites in La Jolla +2 more locations

Sponsor: Rocket Pharmaceuticals Inc.

Sex: Male·Age: 8+

Code: NCT06092034·Phase 2·Recruiting·Listed Oct 2023

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A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

for Severe Hemophilia A

Sites in Los Angeles +2 more locations

Sponsor: Pfizer

Sex: Male·Age: 12 - 74

Code: NCT06703606·Phase 1·Recruiting·Listed Nov 2024

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A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Los Angeles, Duarte +7 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05981703·Phase 1·Recruiting·Listed Aug 2023

Apply to this trial