Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Trial of DFP-14927 in Advanced Solid Tumors

for Solid Tumor

Sites in Los Angeles +1 more location

Sponsor: Delta-Fly Pharma, Inc.

Sex: All·Age: 18+

Code: NCT03943004·Phase 1·Recruiting·Listed May 2019

Apply to this trial

VenusP-Valve Pivotal Study (PROTEUS STUDY)

for Pulmonary Regurgitation

1 location in Irvine

Sponsor: Venus MedTech (HangZhou) Inc.

Sex: All·Age: 12+

Code: NCT06010563·Recruiting·Listed Aug 2023

Apply to this trial

A Study of AMDX-2011P in Participants With Primary Open Angle Glaucoma

for Primary Open Angle Glaucoma

Sites in Newport Beach, Glendale +1 more location

Sponsor: Amydis Inc.

Sex: All·Age: 22+

Code: NCT06223048·Phase 2·Recruiting·Listed Jan 2024

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Kintsugi Voice Device Pivotal Study

for Depression

1 location in Berkeley

Sponsor: Kintsugi Mindful Wellness, Inc.

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT06809907·Recruiting·Listed Feb 2025

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Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS

for ALS (Amyotrophic Lateral Sclerosis)

1 location in Santa Barbara

Sponsor: Cognixion

Sex: All·Age: 18+

Code: NCT06810219·Recruiting·Listed Feb 2025

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A Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics of TIX100 in Healthy Subjects

for Healthy

1 location in Chula Vista

Sponsor: TIXiMED, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06800729·Phase 1·Recruiting·Listed Jan 2025

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Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers

for Diabetic Foot

1 location in Thousand Oaks

Sponsor: Axolotl Biologix

Sex: All·Age: 18+

Code: NCT06550596·Recruiting·Listed Aug 2024

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Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration

for Retinitis Pigmentosa

1 location in Irvine

Sponsor: Ray Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06375239·Recruiting·Listed Apr 2024

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Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for Solid Tumor, Adult

Sites in La Jolla, Stanford +1 more location

Sponsor: BioEclipse Therapeutics

Sex: All·Age: 18+

Code: NCT04282044·Phase 1·Recruiting·Listed Feb 2020

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A Clinical Trial to Assess the Efficacy and Tolerance of a Berberine-based Nutraceutical Formula to Aid Blood Sugar Regulation and Metabolism

for Metabolism Disorder

1 location in Santa Monica

Sponsor: Ultimate International, Inc.

Sex: All·Age: 18 - 70

Code: NCT06700915·Recruiting·Listed Nov 2024

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Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer

for Metastatic Pancreatic Adenocarcinoma

Sites in Whittier +2 more locations

Sponsor: Eleison Pharmaceuticals LLC.

Sex: All·Age: 18+

Code: NCT01954992·Phase 3·Recruiting·Listed Oct 2013

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Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma

for Multiple Myeloma

1 location in West Hollywood

Sponsor: Oncotherapeutics

Sex: All·Age: 18+

Code: NCT06209606·EARLY_Phase 1·Recruiting·Listed Jan 2024

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Telerehabilitation Early After Stroke

for Cerebral Stroke

1 location in Fullerton

Sponsor: TRCare, Inc.

Sex: All·Age: 18+

Code: NCT05625438·Recruiting·Listed Nov 2022

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A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.

for Wounds

Sites in Los Angeles, Castro Valley +2 more locations

Sponsor: Molnlycke Health Care AB

Sex: All·Age: 18+

Code: NCT05588583·Recruiting·Listed Oct 2022

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Urine Metabolites in the Diagnosis of Disease

for Colorectal Cancer

Sites in Santa Monica, Walnut Creek & Encinitas

Sponsor: Luventix, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06710067·Recruiting·Listed Nov 2024

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Controlled Desaturation Study for Perin Health Patch Validation

for Oxygen Saturation Measurement

1 location in Woodland Hills

Sponsor: Perin Health Devices

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06680700·Recruiting·Listed Nov 2024

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Vaginal Photobiomodulation for Chronic Pelvic Pain

for Chronic Pelvic Pain

Sites in San Francisco +4 more locations

Sponsor: SoLa Pelvic Therapy

Sex: Female·Age: 18+

Code: NCT06673108·Phase 2·Recruiting·Listed Nov 2024

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A Study of SPY002-072 in Healthy Volunteers

for Healthy

1 location in Cypress

Sponsor: Spyre Therapeutics, Inc.

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06622070·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

Hyrax Vs. Invisalign Palatal Expander Clinical Study

for Malocclusions

Sites in Laguna Hills +3 more locations

Sponsor: Align Technology, Inc.

Sex: All·Age: 6 - 11

Code: NCT06662279·Recruiting·Listed Oct 2024

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Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

for Hematologic Malignancy

Sites in Duarte +4 more locations

Sponsor: Tr1X, Inc.

Sex: All·Age: 18+

Code: NCT06462365·Phase 1·Recruiting·Listed Jun 2024

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Imaging Immune Activation in HIV by PET-MR

for HIV Infections

1 location in San Francisco

Sponsor: CellSight Technologies, Inc.

Sex: All·Age: 18+

Code: NCT03684655·Phase 2·Recruiting·Listed Sep 2018

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Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

for Intervertebral Disc Degeneration

1 location in Carlsbad

Sponsor: Alphatec Spine, Inc.

Sex: All·Age: 18+

Code: NCT05648474·Recruiting·Listed Dec 2022

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DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

for Leukemia, Myeloid, Acute

Drug: Venetoclax

Sites in Orange +3 more locations

Sponsor: Delta-Fly Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06382168·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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Evaluation of the Performance and Acceptability of a Synthetic Polyisoprene Male Condom Compared to a Natural Rubber Latex Condom

for Condom Use

Sites in Los Angeles & Berkeley

Sponsor: Thai Nippon Rubber Industry Public Company Limited

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06595836·Recruiting·Listed Sep 2024

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Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

for Arrhythmogenic Right Ventricular Cardiomyopathy

Sites in San Francisco +6 more locations

Sponsor: Tenaya Therapeutics

Sex: All·Age: 18 - 65

Code: NCT06228924·Phase 1·Recruiting·Listed Jan 2024

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Validation of Cuffless Blood Pressure Measurements Using the Perin Health Patch

for Blood Pressure

1 location in Woodland Hills

Sponsor: Perin Health Devices

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06574113·Recruiting·Listed Aug 2024

Apply to this trial

The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

for Collagen Degeneration

1 location in Sacramento

Sponsor: Integrative Skin Science and Research

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06571721·Recruiting·Listed Aug 2024

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Local Cerebral Oxygenation in Chronic Pain Patients Utilizing Spinal Cord Stimulation

for Chronic Pain

1 location in Walnut Creek

Sponsor: CereVu Medical, Inc.

Sex: All·Age: 18+

Code: NCT06559735·Recruiting·Listed Aug 2024

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FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

for Alpha-Thalassemia

1 location in Los Altos

Sponsor: xCures

Sex: All·Age: All ages

Code: NCT06539169·Recruiting·Listed Aug 2024

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A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer

for Breast Cancer

1 location in Santa Monica

Sponsor: BriaCell Therapeutics Corporation

Sex: All·Age: 18+

Code: NCT06471673·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

for Open-angle Glaucoma

Sites in Newport Beach, Bakersfield +2 more locations

Sponsor: Amneal Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06267274·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

CareCOPD - COPD Home Monitoring Study

for Chronic Obstructive Pulmonary Disease

1 location in Ventura

Sponsor: Cognita Labs LLC

Sex: All·Age: 40 - 100

Code: NCT04918095·Recruiting·Listed Jun 2021

Apply to this trial

Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy

for Follicular Lymphoma

1 location in Palo Alto

Sponsor: Adaptive Biotechnologies

Sex: All·Age: 18+

Code: NCT05255354·Recruiting·Listed Feb 2022

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Telehealth-delivered HealthcaRe to ImproVe Care

for Telemedicine

1 location in Beverly Hills

Sponsor: Attune Health Research, Inc.

Sex: All·Age: 19+

Code: NCT05483855·Recruiting·Listed Aug 2022

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The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

for Acne

1 location in Sacramento

Sponsor: Integrative Skin Science and Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05942248·Recruiting·Listed Jul 2023

Apply to this trial

Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea

for Rosacea

1 location in Sacramento

Sponsor: Integrative Skin Science and Research

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT06072066·Recruiting·Listed Oct 2023

Apply to this trial

Effectiveness of Qualia NAD+ Supplementation on Intracellular NAD Levels

for NAD+ Levels in the Blood

1 location in Carlsbad

Sponsor: Qualia Life Sciences

Sex: All·Age: 40 - 65·Accepts healthy volunteers

Code: NCT06505967·Recruiting·Listed Jul 2024

Apply to this trial

A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing

for Wounds

Sites in San Francisco +2 more locations

Sponsor: Molnlycke Health Care AB

Sex: All·Age: 18+

Code: NCT05608317·Recruiting·Listed Nov 2022

Apply to this trial

Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer

for Colorectal Neoplasms

Sites in La Jolla, Duarte +4 more locations

Sponsor: Surgimab

Sex: All·Age: 18+

Code: NCT03659448·Phase 3·Recruiting·Listed Sep 2018

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Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

for Congestive Heart Failure

Sites in San Francisco, San Diego +3 more locations

Sponsor: Sardocor Corp.

Sex: All·Age: 18 - 80

Code: NCT04703842·Phase 1, Phase 2·Recruiting·Listed Jan 2021

Apply to this trial