Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for Acute Myeloid Leukemia

Sites in Duarte +2 more locations

Sponsor: Edgewood Oncology Inc.

Sex: All·Age: 18+

Code: NCT04243785·Phase 1·Recruiting·Listed Jan 2020

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Data Collection and Evaluation of OptiBP Under Investigational Use

for General Population

1 location in Truckee

Sponsor: Biospectal

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06017687·Recruiting·Listed Aug 2023

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Phase 2 Clinical Trial of CartiLife® in the United States

for Articular Cartilage Defect

Sites in Irvine, La Mesa +3 more locations

Sponsor: Biosolution Co., Ltd.

Sex: All·Age: 18+

Code: NCT04744402·Phase 2·Recruiting·Listed Feb 2021

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Dose Regimen Study of SLI-F06 in Healthy Volunteers

for Scar

Sites in Encinitas +1 more location

Sponsor: Scarless Laboratories, Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05501327·Phase 2·Recruiting·Listed Aug 2022

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Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*)

for Metastatic Breast Cancer

1 location in Duarte

Sponsor: Minerva Biotechnologies Corporation

Sex: All·Age: 18+

Code: NCT04020575·Phase 1·Recruiting·Listed Jul 2019

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Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

for Glaucoma, Open-Angle

Sites in Newport Beach, Petaluma +7 more locations

Sponsor: Amneal Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT05401357·Phase 3·Recruiting·Listed Jun 2022

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Traumatic Brain Injury and Stroke Long Term Outcome

for Traumatic Brain Injury

1 location in Encino

Sponsor: Centre for Neuro Skills

Sex: All·Age: 18+

Code: NCT03399929·Recruiting·Listed Jan 2018

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A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of the Dayspring Technology for Patients With Breast Cancer Related Lymphedema (BCRL) After Lymphatic Surgery

for Lymphedema

1 location in Palo Alto

Sponsor: Koya Medical, Inc.

Sex: All·Age: 18+

Code: NCT04888975·Recruiting·Listed May 2021

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ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma

for Carcinoma, Hepatocellular

Drug: Nivolumab

Sites in La Jolla +1 more location

Sponsor: Abivax S.A.

Sex: All·Age: 18+

Code: NCT03897543·Phase 1, Phase 2·Recruiting·Listed Apr 2019

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Digital and Plasma Biomarkers in Delirium

for Critical Illness

Sites in San Diego & La Jolla

Sponsor: Scripps Health

Sex: All·Age: 65+

Code: NCT07694206·Recruiting·Listed Jul 9, 2026

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UHFUS Characterization of Normal Lymphatic Anatomy

for Breast Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT07677839·Recruiting·Listed Jul 1, 2026

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Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

for Duchenne Muscular Dystrophy (DMD)

Sites in Sacramento +8 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT07674758·Recruiting·Listed Jun 30, 2026

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Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study

for Type 1 Diabetes

Sites in Newport Beach +6 more locations

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07676565·Recruiting·Listed Jun 30, 2026

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Precision Pain Management - A Randomized Clinical Trial Assessing the Efficacy of Suzetrigine on Postoperative Analgesia Among Surgical Patients at Higher Risk for Persistent Postoperative Opioid Use (POU)

for Opioid Consumption, Postoperative

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT07672015·Phase 4·Recruiting·Listed Jun 26, 2026

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Empowering Monterey Bay Residents for Activated, Collaborative, and Equitable Care

for Shared Decision-Making

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT07652359·Recruiting·Listed Jun 17, 2026

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CAMPR-II RWE TRIAL: A Saline-hydrated Allogeneic Dual-layer Amniotic Membrane Product or a Synthetic, Resorbable Polymeric Wound Matrix to a Coarsened Exact Matched Retrospective Control Cohort of Hard to Heal DFUs and VLUs

for Wound, Foot

Sites in San Diego +6 more locations

Sponsor: Capsicure, LLC

Sex: All·Age: 18+

Code: NCT07701590·Recruiting·Listed Jul 14, 2026

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Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use

for Nicotine Dependence

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21 - 55·Accepts healthy volunteers

Code: NCT07698470·Recruiting·Listed Jul 13, 2026

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Cognitive and Electrophysiological Assessment of Non-Invasive Temporally-Interfering Electric Fields Stimulation (TIEFS)

for Epilepsy

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07663578·Recruiting·Listed Jun 23, 2026

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Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms

for Appendiceal Mucinous Neoplasm

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07693452·Phase 2·Recruiting·Listed Jul 9, 2026

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Social, Structural, and Lifestyle Drivers of Prostate Cancer Disparities

for Prostate Cancer

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT07690579·Recruiting·Listed Jul 8, 2026

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Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions

for Cesarean Section

1 location in Moreno Valley

Sponsor: Riverside University Health System Medical Center

Sex: Female·Age: 18+

Code: NCT07686913·Recruiting·Listed Jul 7, 2026

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PEP/PrEP Via Pharmacist-Prescribing Implementation (PEPPI)

for HIV Prevention

1 location in Del Mar

Sponsor: EMPOWERX INC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07683117·Recruiting·Listed Jul 6, 2026

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Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy

for Drug-Resistant Epilepsy

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 21 - 65

Code: NCT07680842·Recruiting·Listed Jul 2, 2026

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Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator

for PD - Parkinson's Disease

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 25 - 75

Code: NCT07682311·Recruiting·Listed Jul 2, 2026

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Ongoing Lung Decline With Age Intensified Response

for Age-Related Lung Function Decline

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07676435·Phase 2·Recruiting·Listed Jun 30, 2026

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Pilot Study Exploring the Effects of Rhythmic Auditory Stimulation on Gait in People With Motor Incomplete Spinal Cord Injury

for Spinal Cord Injury

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT07674927·Recruiting·Listed Jun 30, 2026

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Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid Tumors

for Solid Tumor Cancer

1 location in Santa Monica

Sponsor: Sarcoma Oncology Research Center, LLC

Sex: All·Age: 18+

Code: NCT07671534·Phase 2·Recruiting·Listed Jun 26, 2026

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Multivitamin and Mineral Supplementation and Healthy Aging

for Healthy Aging

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 40 - 60·Accepts healthy volunteers

Code: NCT07642869·Recruiting·Listed Jun 11, 2026

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Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07664579·Recruiting·Listed Jun 24, 2026

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Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

Sites in Orange +15 more locations

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting·Listed Jun 4, 2026

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Fluorescence-Guided Surgical Resection for Reducing Unexpected Positive Margins in Patients With Sarcoma, SarcoSIGHT Trial

for High Grade Sarcoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: All ages

Code: NCT07650656·Phase 2·Recruiting·Listed Jun 16, 2026

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Outcomes Associated With Tirbanibulin for Large Field Application on the Face in the U.S (CLEAR)

for Actinic Keratosis (AK)

Sites in Manhattan Beach +1 more location

Sponsor: Avant Health LLC

Sex: All·Age: 18+

Code: NCT07657988·Recruiting·Listed Jun 18, 2026

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

Sites in Palo Alto, Fullerton +12 more locations

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting·Listed May 2026

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Teen Helpline Motivational Interviewing Study

for Implementation Research

1 location in San Diego

Sponsor: San Diego State University

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07639736·Recruiting·Listed Jun 10, 2026

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Lung and Heart Function Across Decades of Life in Health

for Pollution Related Respiratory Disorder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 24 - 68·Accepts healthy volunteers

Code: NCT07641413·Recruiting·Listed Jun 11, 2026

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Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses

for Contact Lens Comfort and Successful Refitting

1 location in La Jolla

Sponsor: Gordon Schanzlin New Vision

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT07638943·Recruiting·Listed Jun 10, 2026

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Smart Discharges for Older Children

for Sepsis

Sites in San Francisco +2 more locations

Sponsor: University of British Columbia

Sex: All·Age: 5 - 16

Code: NCT07629154·Recruiting·Listed Jun 5, 2026

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RAD ONC FREEDOM Oncology Pain

for Cancer Pain

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07605546·Recruiting·Listed May 2026

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Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study

for Cancer

Sites in Orange & Irvine

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07581080·Recruiting·Listed May 2026

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Multi-Site Trial of Tirzepatide for Smoking Cessation

for Smoking Cessation

Drug: Tirzepatide

Sites in Los Angeles +3 more locations

Sponsor: University of Southern California

Sex: All·Age: 21 - 65

Code: NCT07602699·Phase 2·Recruiting·Listed May 2026

Apply to this trial