Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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5,273 clinical trials

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A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Los Angeles, San Francisco +44 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting·Listed May 2025

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Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

for Agitation

Sites in La Jolla, Anaheim +45 more locations

Sponsor: Celgene

Sex: All·Age: 55 - 90

Code: NCT06808984·Phase 2·Recruiting·Listed Feb 2025

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A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for Endometrial Cancer

Sites in Orange, Irvine +44 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06952504·Phase 3·Recruiting·Listed May 2025

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Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

for High-Risk Non-Muscle-Invasive Bladder Cancer

Sites in San Diego, Sacramento +73 more locations

Sponsor: CG Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06567743·Phase 2·Recruiting·Listed Aug 2024

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A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for Breast Neoplasms

Sites in Fullerton, Los Alamitos +39 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312176·Phase 3·Recruiting·Listed Mar 2024

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Assessment of CCM in HF With Higher Ejection Fraction

for Heart Failure

Sites in Los Angeles, La Jolla +74 more locations

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT05064709·Recruiting·Listed Oct 2021

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

Sites in Los Angeles, San Francisco +66 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting·Listed Mar 2025

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Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for Neovascular Age-related Macular Degeneration

Drug: Surabgene Lomparvovec

Sites in San Francisco, Sacramento +51 more locations

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07007065·Phase 3·Recruiting·Listed Jun 2025

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

Sites in Long Beach, Loma Linda +48 more locations

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting·Listed Mar 2025

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Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

for Acute Myeloid Leukemia (AML)

Sites in Los Angeles, La Jolla +40 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07007312·Phase 3·Recruiting·Listed Jun 2025

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Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

for Migraine

Drug: Rimegepant

Sites in Hawthorne +30 more locations

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT05156398·Phase 3·Recruiting·Listed Dec 2021

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Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

for Alzheimer Disease

Sites in Orange, Oakland +36 more locations

Sponsor: Lighthouse Pharmaceuticals, Inc.

Sex: All·Age: 55 - 80

Code: NCT06847321·Phase 2·Recruiting·Listed Feb 2025

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A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

for RSV Infection

Sites in Los Angeles, Palo Alto +78 more locations

Sponsor: Pfizer

Sex: All·Age: 0+·Accepts healthy volunteers

Code: NCT06866405·Phase 3·Recruiting·Listed Mar 2025

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Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

for Prostate Cancer Metastatic

Sites in Palo Alto, Riverside +31 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06136624·Phase 3·Recruiting·Listed Nov 2023

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A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

Sites in San Diego, La Jolla +66 more locations

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting·Listed Oct 2024

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A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for Advanced Cancer

Sites in Los Angeles, Santa Rosa +36 more locations

Sponsor: Artios Pharma Ltd

Sex: All·Age: 18+

Code: NCT04657068·Phase 1, Phase 2·Recruiting·Listed Dec 2020

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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for Hypertension

Sites in San Francisco, Newport Beach +54 more locations

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT06059638·Recruiting·Listed Sep 2023

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A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for Obstructive Hypertrophic Cardiomyopathy

Drug: Mavacamten

Sites in Los Angeles, San Francisco +46 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05489705·Recruiting·Listed Aug 2022

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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

for Chronic Kidney Disease

Drug: Empagliflozin

Sites in Los Angeles, San Francisco +25 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07107945·Phase 3·Recruiting·Listed Aug 2025

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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for Refractory Angina

Sites in Los Angeles, San Francisco +64 more locations

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT05102019·Recruiting·Listed Nov 2021

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

Sites in San Francisco, Duarte +76 more locations

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting·Listed Feb 2018

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A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for Metastatic Colorectal Cancer

Sites in Los Angeles, Duarte +18 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04929223·Phase 1·Recruiting·Listed Jun 2021

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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

Sites in Los Angeles, Palo Alto +43 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting·Listed Nov 2023

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A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for Cachexia

Drug: ponsegromab

Sites in Los Angeles, San Diego +81 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06989437·Phase 2, Phase 3·Recruiting·Listed May 2025

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

Sites in Duarte +55 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting·Listed Feb 2025

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A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

for Diffuse Large B-Cell Lymphoma

Drug: Rituximab

Sites in Los Angeles, San Francisco +45 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06717347·Phase 3·Recruiting·Listed Dec 2024

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

Sites in Los Angeles, San Francisco +35 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting·Listed Jul 2023

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for Breast Neoplasms

Sites in Los Angeles, Stanford +36 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06926868·Phase 2, Phase 3·Recruiting·Listed Apr 2025

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A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for Low Grade Serous Ovarian Cancer

Drug: Avutometinib

Sites in Los Angeles, Sacramento +34 more locations

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT06072781·Phase 3·Recruiting·Listed Oct 2023

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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

Sites in Los Angeles, Palo Alto +43 more locations

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting·Listed Nov 2024

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Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

for Depressive Disorder, Major

Drug: Seltorexant

Sites in Anaheim, Glendale +42 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT06559306·Phase 3·Recruiting·Listed Aug 2024

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A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

for Multiple Myeloma

Sites in San Francisco, Duarte +26 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05201781·Phase 4·Recruiting·Listed Jan 2022

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SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

Sites in Los Angeles, San Francisco +44 more locations

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting·Listed Mar 2022

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A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for Carcinoma, Non-Small-Cell Lung

Drug: Intismeran autogene

Sites in Los Angeles, San Francisco +48 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06623422·Phase 3·Recruiting·Listed Oct 2024

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Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

Sites in Los Angeles, San Francisco +50 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting·Listed Sep 2023

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Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

for Heart Failure

Sites in San Francisco, Concord +30 more locations

Sponsor: Procyrion

Sex: All·Age: 21+

Code: NCT05677100·Recruiting·Listed Jan 2023

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This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

for Non-Small Cell Lung Cancer

Drug: sigvotatug vedotin

Sites in Fullerton +74 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06758401·Phase 3·Recruiting·Listed Jan 2025

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A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

for Small-cell Lung Cancer

Drug: Durvalumab

Sites in Los Angeles, Santa Monica +48 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07005128·Phase 3·Recruiting·Listed Jun 2025

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A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for Non-small Cell Lung Cancer

Drug: Intismeran autogene

Sites in Los Angeles, Orange +56 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06077760·Phase 3·Recruiting·Listed Oct 2023

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A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for Mantle Cell Lymphoma

Drug: Sonrotoclax

Sites in Irvine, Fresno +39 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06742996·Phase 3·Recruiting·Listed Dec 2024

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