Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

Sites in Duarte +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting·Listed Jul 2023

Apply to this trial

fMRI Neurofeedback With Matter Neuroscience App

for Depression Mild

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 80

Code: NCT06735885·Recruiting·Listed Dec 2024

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Sacramento, Loma Linda +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

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Predicting BCG Response

for Bladder Cancer

Sites in Los Angeles, San Francisco +2 more locations

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 90

Code: NCT04564781·Recruiting·Listed Sep 2020

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Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis

for De Quervain Tenosynovitis

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT04895956·Phase 4·Recruiting·Listed May 2021

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Los Angeles, San Francisco +78 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

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SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

Sites in Los Angeles, San Francisco +12 more locations

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting·Listed Sep 2021

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Automated Robotic TCD in Traumatic Brain Injury

for Brain Injuries, Traumatic

Sites in Davis +2 more locations

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18+

Code: NCT05848297·Recruiting·Listed May 2023

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CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

for Trauma

Sites in San Francisco +14 more locations

Sponsor: Jason Sperry

Sex: All·Age: 18 - 90

Code: NCT05958342·Phase 2·Recruiting·Listed Jul 2023

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Using Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department

for Opioid Use Disorder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06872190·Recruiting·Listed Mar 2025

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Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial

for Chronic Lymphocytic Leukemia

Drug: Epcoritamab

Sites in Duarte, Irvine +5 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07218510·Phase 2·Recruiting·Listed Oct 2025

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Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer

for Thyroid Cancer

1 location in San Francisco

Sponsor: Thomas Hope

Sex: All·Age: 13+

Code: NCT06961084·Phase 2·Recruiting·Listed May 2025

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Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)

for PASC Post Acute Sequelae of COVID-19

Sites in San Francisco & Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07076862·EARLY_Phase 1·Recruiting·Listed Jul 2025

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TERPS Trial for de Novo Oligometastic Prostate Cancer

for Prostate Cancer

Sites in La Jolla +9 more locations

Sponsor: University of Maryland, Baltimore

Sex: Male·Age: 18+

Code: NCT05223803·Phase 2·Recruiting·Listed Feb 2022

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Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification

for Prostate Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male·Age: 18+

Code: NCT04765150·Recruiting·Listed Feb 2021

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ALS/MND Natural History Study Data Repository

for ALS

Sites in Los Angeles, Loma Linda +12 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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Stratified Pharmacological Approaches for Regulating Circuit-Level Effects

for Depression - Major Depressive Disorder

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 65

Code: NCT07022405·Phase 2·Recruiting·Listed Jun 2025

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COES: Curing Order Effects on Sealants

for Dental Sealant

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 5 - 14·Accepts healthy volunteers

Code: NCT06342258·Phase 1·Recruiting·Listed Apr 2024

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Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

for Multiple Sclerosis (MS)

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 55

Code: NCT05359653·Phase 1, Phase 2·Recruiting·Listed May 2022

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Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)

for Small Bowel Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06101277·Recruiting·Listed Oct 2023

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Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

for Post Traumatic Stress Disorder (PTSD)

Sites in San Diego +2 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06162741·Recruiting·Listed Dec 2023

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Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT06815003·Phase 2·Recruiting·Listed Feb 2025

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Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

for Recurrent Astrocytoma, IDH-Mutant, Grade 3

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06815029·Phase 1·Recruiting·Listed Feb 2025

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Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

for Anarthria

Sites in Stanford +1 more location

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT05724173·Recruiting·Listed Feb 2023

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Effect of Gerofit Exercise on Cognition in Older Veterans

for Aging

Sites in West Los Angeles +1 more location

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06107842·Recruiting·Listed Oct 2023

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Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06500377·Recruiting·Listed Jul 2024

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Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

for Sleep Apnea, Obstructive

1 location in Santa Monica

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT00695214·Phase 2·Recruiting·Listed Jun 2008

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Delayed Blood Stem Transplantation in HLA Matched Kidney Transplant Recipients to Eliminate Immunosuppressive Drugs.

for Immune Tolerance

1 location in Palo Alto

Sponsor: Stephan Busque

Sex: All·Age: 18+

Code: NCT03591302·Phase 1·Recruiting·Listed Jul 2018

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Mogamulizumab + Low-Dose Total Skin Electron Beam Tx in Mycosis Fungoides & Sézary Syndrome

for Sezary Syndrome

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT04256018·Phase 2·Recruiting·Listed Feb 2020

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Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer

for Platinum-Resistant Ovarian Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT05225363·Phase 1·Recruiting·Listed Feb 2022

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An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for Anatomic Stage IV Breast Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05376878·Phase 4·Recruiting·Listed May 2022

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Endotypic Traits and Obstructive Sleep Apnea Surgery

for Obstructive Sleep Apnea

Sites in Santa Monica & Westwood, Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 21+

Code: NCT05953610·Phase 2·Recruiting·Listed Jul 2023

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Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

for Bone Disease, Metabolic

1 location in San Diego

Sponsor: San Diego State University

Sex: Female·Age: All ages

Code: NCT06184646·Recruiting·Listed Dec 2023

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Los Angeles, San Francisco +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

for Rectal Adenocarcinoma

Drug: Botensilimab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06780787·Phase 2·Recruiting·Listed Jan 2025

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Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

for Brain Tumor

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 6 Months - 25

Code: NCT04085887·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

Sites in Duarte +1 more location

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05136846·Phase 1·Recruiting·Listed Nov 2021

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Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma

for Double-Expressor Lymphoma

Drug: Rituximab

Sites in San Diego & Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT05600686·Phase 2·Recruiting·Listed Oct 2022

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Blossom® Smart Expander Device for Tissue Expander/Implant-Based Breast Reconstruction

for Tissue Expansion

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05975372·Recruiting·Listed Aug 2023

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Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER)

for Prostate Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06101290·Recruiting·Listed Oct 2023

Apply to this trial