Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors

for Anatomic Stage I Breast Cancer American Joint Committee on Cancer (AJCC) v8

Sites in Los Angeles, Beverly Hills +4 more locations

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Female·Age: All ages

Code: NCT06113016·Phase 2·Recruiting·Listed Nov 2023

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Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

for Breast Cancer

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT06580002·Phase 2·Recruiting·Listed Aug 2024

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Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas

for Low-grade Glioma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03948490·Recruiting·Listed May 2019

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Improving Survivorship Care for Older Adults After Chemotherapy

for Survivorship

1 location in Clovis

Sponsor: University of California, San Francisco

Sex: All·Age: 65+

Code: NCT04405115·Recruiting·Listed May 2020

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Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

for Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation

Sites in Los Angeles, Duarte +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05691465·Phase 2·Recruiting·Listed Jan 2023

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Chronic Thromboembolic Disease Registry

for Chronic Thromboembolic Pulmonary Hypertension

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05843500·Recruiting·Listed May 2023

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Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial

for Glaucoma

Sites in San Francisco, Walnut Creek +5 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05924477·Recruiting·Listed Jun 2023

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Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer

for Lung Cancer

Sites in Los Angeles +2 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06427954·Recruiting·Listed May 2024

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A Single-Stage, Adaptive, Open-label, Dose Escalation Safety and Efficacy Study of AADC Deficiency in Pediatric Patients

for AADC Deficiency

Sites in San Francisco +2 more locations

Sponsor: Krzysztof Bankiewicz

Sex: All·Age: 24 Months+

Code: NCT02852213·Phase 1·Recruiting·Listed Aug 2016

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An Evaluation of Maintenance Therapy Combination Mirvetuximab Soravtansine and Olaparib

for Ovary Cancer

Sites in Irvine +5 more locations

Sponsor: University of Colorado, Denver

Sex: Female·Age: 18 - 100

Code: NCT05887609·Phase 2·Recruiting·Listed Jun 2023

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Cultural Adaptation of Drug Treatment for DJJ Youth

for Substance Use

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 13 - 17·Accepts healthy volunteers

Code: NCT06003725·Recruiting·Listed Aug 2023

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Tafasitamab Plus Lenalidomide in Relapsed CNS Lymphoma

for CNS Lymphoma

Drug: Tafasitamab

1 location in San Francisco

Sponsor: James Rubenstein

Sex: All·Age: 18+

Code: NCT05351593·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

Sites in Los Angeles, San Francisco +13 more locations

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting·Listed Mar 2012

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Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A

for Fungal Keratitis

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06658002·Phase 3·Recruiting·Listed Oct 2024

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Biomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With Edaravone

for Amyotrophic Lateral Sclerosis

1 location in Loma Linda

Sponsor: Loma Linda University

Sex: All·Age: 18 - 85

Code: NCT04097158·Recruiting·Listed Sep 2019

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

Sites in La Jolla +10 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting·Listed Jul 2021

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The Effects of Endotracheal Suctioning on Pain and Serum Markers

for Intensive Care Unit ICU

1 location in Loma Linda

Sponsor: Loma Linda University

Sex: All·Age: 18+

Code: NCT06692400·Recruiting·Listed Nov 2024

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The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

Sites in San Francisco +11 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting·Listed Mar 2025

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Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin Lymphoma

for Advanced Hodgkin Lymphoma

Sites in Palo Alto, Irvine +4 more locations

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT06745076·Phase 2·Recruiting·Listed Dec 2024

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Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities

for Tobacco-Related Carcinoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07049757·Recruiting·Listed Jul 2025

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Prescreening Protocol to Enroll in Food Allergy Clinical Studies at a Single Site

for Food Allergy

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 1 Week - 90

Code: NCT03539692·Recruiting·Listed May 2018

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A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness

for Psychotic Disorders

1 location in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05537376·Recruiting·Listed Sep 2022

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Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Mosunetuzumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672251·Phase 2·Recruiting·Listed Jan 2023

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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

for Heart Failure

Drug: Finerenone

Sites in San Francisco, San Diego +52 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06033950·Phase 3·Recruiting·Listed Sep 2023

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Abuse Liability and Appeal of Oral Nicotine Products

for Nicotine Dependence

2 locations in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21 - 25·Accepts healthy volunteers

Code: NCT06506162·Recruiting·Listed Jul 2024

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Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys

for HIV Infections

2 locations in San Clemente

Sponsor: Center for Innovative Public Health Research

Sex: Male·Age: 13 - 22·Accepts healthy volunteers

Code: NCT06230367·Recruiting·Listed Jan 2024

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Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

for Adult Growth Hormone Deficiency

Sites in San Diego +14 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 21 - 55

Code: NCT04867317·Phase 3·Recruiting·Listed Apr 2021

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in San Francisco, San Diego +67 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

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Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Epcoritamab

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06905509·Phase 2·Recruiting·Listed Apr 2025

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Los Angeles, San Francisco +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

for Acute Graft Versus Host Disease

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05443425·Phase 1·Recruiting·Listed Jul 2022

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Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

for Breast Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06103669·Recruiting·Listed Oct 2023

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LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)

for Non-small Cell Lung Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06103682·Recruiting·Listed Oct 2023

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Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

for Lung Non-Small Cell Carcinoma

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06139627·Recruiting·Listed Nov 2023

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Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

for Metastatic Castration-Resistant Prostate Carcinoma

Sites in San Francisco, Sylmar +1 more location

Sponsor: University of Washington

Sex: Male·Age: 18+

Code: NCT06526299·Phase 2·Recruiting·Listed Jul 2024

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Early Onset Colorectal Cancer Detection

for Colorectal Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06342401·Recruiting·Listed Apr 2024

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An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for Hepatocellular Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06342414·Recruiting·Listed Apr 2024

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Stage II/III Colorectal Cancer Recurrence

for Colorectal Cancer

1 location in Monrovia

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06314958·Recruiting·Listed Mar 2024

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Brain Health in Breast Cancer Survivors

for Cognitive Impairment

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Female·Age: 35 - 65·Accepts healthy volunteers

Code: NCT04297020·Recruiting·Listed Mar 2020

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Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

for Metastatic Dedifferentiated Liposarcoma

Drug: Peposertib

Sites in Los Angeles +14 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05711615·Phase 1·Recruiting·Listed Feb 2023

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