Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

for Clinical Stage IA Cutaneous Melanoma AJCC v8

Sites in Davis +4 more locations

Sponsor: OHSU Knight Cancer Institute

Sex: All·Age: 18+

Code: NCT06673095·Recruiting·Listed Nov 2024

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Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

for Colorectal Carcinoma

Sites in San Francisco +8 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05410977·Recruiting·Listed Jun 2022

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A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

for Advanced Melanoma

Drug: Cemiplimab

Sites in Los Angeles, Stanford +10 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06594991·Phase 2·Recruiting·Listed Sep 2024

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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for Pediatric Patients Treated With Radiation Therapy

Sites in San Francisco, San Diego +21 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 21

Code: NCT01696721·Recruiting·Listed Oct 2012

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TReatment for ImmUne Mediated PathopHysiology

for Acute Liver Failure

Sites in Los Angeles, San Diego +15 more locations

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 1 - 18

Code: NCT04862221·Phase 2·Recruiting·Listed Apr 2021

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Effectiveness of Cognitive Training in Older and Younger Adults

for Cognitive Change

Sites in Riverside +2 more locations

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06375681·Recruiting·Listed Apr 2024

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Los Angeles, San Francisco +161 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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Computational Assessment of GABA Receptor Modulation in PTSD

for Stress Disorders, Post-Traumatic

1 location in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06852469·Phase 4·Recruiting·Listed Feb 2025

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Los Angeles, San Francisco +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Engagement of Veterans With Lung Cancer

for Lung Cancer (NSCLC)

1 location in Palo Alto

Sponsor: Palo Alto Veterans Institute for Research

Sex: All·Age: 18+

Code: NCT07219251·Recruiting·Listed Oct 2025

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Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

for Crohn Disease (CD)

Sites in Beverly Hills +2 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06976853·Phase 2·Recruiting·Listed May 2025

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NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver Disease

for Positron Emission Tomography

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06453915·EARLY_Phase 1·Recruiting·Listed Jun 2024

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Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

for Glioblastoma, IDH-Wildtype

Sites in Los Angeles +11 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06319027·Phase 2·Recruiting·Listed Mar 2024

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Creatine Supplementation in Concussion Recovery

for Concussion, Brain

1 location in San Diego

Sponsor: San Diego State University

Sex: All·Age: 18 - 35

Code: NCT06208813·Recruiting·Listed Jan 2024

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Hyperpolarized Imaging in Diagnosing Participants With Glioma

for Glioma

1 location in San Francisco

Sponsor: Susan Chang

Sex: All·Age: 19+

Code: NCT03739411·Phase 1·Recruiting·Listed Nov 2018

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Combination Therapy in Cancers With Mutations in DNA Repair Genes

for Metastatic Solid Tumor

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05694715·Phase 1·Recruiting·Listed Jan 2023

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Investigation of Locus Coeruleus Function in Sustained Attention

for Attention - no Condition is Being Assessed - Healthy Adults

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06041048·Phase 4·Recruiting·Listed Sep 2023

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People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity

for HIV Infections

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06055868·Recruiting·Listed Sep 2023

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Water-based Activity to Enhance Recovery in Long COVID-19

for Long COVID

1 location in Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 89

Code: NCT06142253·Recruiting·Listed Nov 2023

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Single Time Point Prediction as Earlier Diagnosis of Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT06162884·Recruiting·Listed Dec 2023

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Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal Carcinoma

for Nasopharyngeal Carcinoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06682442·Recruiting·Listed Nov 2024

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Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

for Major Depressive Disorder

1 location in Sunnyvale

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65

Code: NCT06376734·Phase 2·Recruiting·Listed Apr 2024

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Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer

for Renal Pelvis and Ureter Urothelial Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05775471·Phase 2·Recruiting·Listed Mar 2023

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Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in San Francisco +1 more location

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT06518057·Phase 2·Recruiting·Listed Jul 2024

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Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults

for HIV

Sites in Los Angeles +1 more location

Sponsor: Westat

Sex: All·Age: 16 - 24·Accepts healthy volunteers

Code: NCT06444360·Recruiting·Listed Jun 2024

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8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05263284·Phase 1·Recruiting·Listed Mar 2022

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Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for Anatomic Stage III Breast Cancer AJCC v8

Sites in Los Angeles, Newport Beach +5 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05372640·Phase 1·Recruiting·Listed May 2022

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Dulce Digital 2.0 - Innovative Diabetes Self-Management in the Digital Age

for Diabetes Type 2

Sites in San Diego & Chula Vista

Sponsor: Scripps Whittier Diabetes Institute

Sex: All·Age: 18+

Code: NCT05416060·Recruiting·Listed Jun 2022

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Registry Study for Radiation Therapy Outcomes

for Neoplasms

Sites in San Diego +28 more locations

Sponsor: Proton Collaborative Group

Sex: All·Age: All ages

Code: NCT01255748·Recruiting·Listed Dec 2010

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Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation

for Prosthetic Valve Thrombosis

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT02318342·Recruiting·Listed Dec 2014

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Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial

for Knee Osteoarthritis

Sites in Sacramento +1 more location

Sponsor: University of California, Davis

Sex: All·Age: 35 - 99

Code: NCT04472702·Recruiting·Listed Jul 2020

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Melanin and Dermal Uptake of Thirdhand Cigarette Smoke

for Healthy

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06020248·Recruiting·Listed Aug 2023

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Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures

for Healthy

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 21 - 50·Accepts healthy volunteers

Code: NCT06030674·Recruiting·Listed Sep 2023

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Tocilizumab in Lung Transplantation

for Lung Transplant

Drug: Tocilizumab

Sites in Los Angeles, Beverly Hills +15 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75

Code: NCT06033196·Phase 2·Recruiting·Listed Sep 2023

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Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

for Metastatic Microsatellite Stable Colorectal Carcinoma

Sites in Orange, Irvine +6 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06654037·Phase 1·Recruiting·Listed Oct 2024

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Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture

for Fibromyalgia

1 location in Irvine

Sponsor: University of California, Irvine

Sex: All·Age: 18 - 80

Code: NCT06571110·Recruiting·Listed Aug 2024

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An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer

for Clear Cell Renal Cell Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06447103·Phase 2·Recruiting·Listed Jun 2024

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CONNECTing to LungCare

for Smoking Cessation

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06213532·Recruiting·Listed Jan 2024

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THC Effects on Glucose in Type 2 Diabetes

for Type 2 Diabetes

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 21 - 70

Code: NCT05322213·Phase 1·Recruiting·Listed Apr 2022

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Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma

for Multiple Myeloma

1 location in San Francisco

Sponsor: Robert Flavell, MD, PhD

Sex: All·Age: 18+

Code: NCT05892393·Phase 1·Recruiting·Listed Jun 2023

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