Clinical Trials at Medical University of South Carolina

As of September 2026, 338 paid clinical trials are recruiting at Medical University of South Carolina, located at 96 JONATHAN LUCAS ST, SUITE 309, CHARLESTON, SC 29425-8900, phone (843) 792-3221 in Charleston, South Carolina. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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339 clinical trials at Medical University of South Carolina

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

Sites in Charleston +39 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting·Listed Mar 2016

Apply to this trial

Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)

for Generalized Anxiety Disorder

Sites in Charleston +2 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 65

Code: NCT04557891·Recruiting·Listed Sep 2020

Apply to this trial

The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

for Sleep Apnea, Obstructive

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 12

Code: NCT06828835·Recruiting·Listed Feb 2025

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Brief Family Involved Treatment Telehealth

for Alcohol Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT05674409·Recruiting·Listed Jan 2023

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Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

for Lower Back Pain

2 locations in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07166952·Recruiting·Listed Sep 2025

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CARS: Cannabis and Alcohol Reduction Study

for Cannabis Use

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 13 - 17

Code: NCT05486234·Recruiting·Listed Aug 2022

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Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)

for Lymphangioleiomyomatosis (LAM)

Sites in Charleston +1 more location

Sponsor: Columbia University

Sex: Female·Age: 18 - 64

Code: NCT06889168·Phase 1·Recruiting·Listed Mar 2025

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Health Outcomes of Parents With Cystic Fibrosis-Aim 2

for Cystic Fibrosis

Sites in Charleston +17 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06296394·Recruiting·Listed Mar 2024

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Reduction of Myopotential Interference With Smart Pass in S-ICD Patients

for Subcutaneous ICD

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05766943·Recruiting·Listed Mar 2023

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Optimizing Tobacco Treatment Delivery for People Living With HIV

for Hiv

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT05019495·Recruiting·Listed Aug 2021

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IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

for Nontuberculous Mycobacterium Infection

Sites in Charleston +9 more locations

Sponsor: Chris Goss

Sex: All·Age: 18+

Code: NCT04294043·Phase 1·Recruiting·Listed Mar 2020

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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in Charleston +129 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

Apply to this trial

Formoterol in Diabetes

for Diabetic Nephropathies

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07022418·Phase 2·Recruiting·Listed Jun 2025

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Physical Capacity Building for Chronic Stroke

for Stroke

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 80

Code: NCT07039305·Recruiting·Listed Jun 2025

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Autophagy Maintenance (AUTOMAIN)

for Ovarian Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06971744·Phase 2·Recruiting·Listed May 2025

Apply to this trial

RM1 Project 1 - tAN Naloxone

for Analgesia

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05490134·EARLY_Phase 1·Recruiting·Listed Aug 2022

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sTMS Combined With CIMT and taVNS In Infants With Hemiplegia

for Hemiplegia

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 8 Months - 24 Months

Code: NCT07063446·Recruiting·Listed Jul 2025

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Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

for Head and Neck Cancer

Sites in Charleston +3 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05793151·Recruiting·Listed Mar 2023

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SMYLS Multi-site Trial

for Sickle Cell Disease

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 14 - 21·Accepts healthy volunteers

Code: NCT06035939·Recruiting·Listed Sep 2023

Apply to this trial

Integrated Treatment for Opioid Use Disorder and PTSD

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 70

Code: NCT06641115·Recruiting·Listed Oct 2024

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ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain

for Opioid Withdrawal

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06442566·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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Quantitative Cardiac Parametric Mapping

for Cardiomyopathy, Myocarditis, Ischemic Heart Disease

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT02855554·Recruiting·Listed Aug 2016

Apply to this trial

SCORE Emerging Adult Cannabis Use & Stress

for Cannabis Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 25

Code: NCT05885542·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

AFO Prescription to Optimize Post-Stroke Function

for Ankle Foot Orthosis (AFO)

Sites in Charleston +3 more locations

Sponsor: University of Texas at Austin

Sex: All·Age: 18+

Code: NCT06692686·Recruiting·Listed Nov 2024

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Optimizing Care for Cancer Survivors With Depression: Project 3

for Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06930729·Recruiting·Listed Apr 2025

Apply to this trial

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

for Deep Brain Stimulation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06960096·Recruiting·Listed May 2025

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NAC vs Placebo on Opioid Use for Hysterectomy

for Hysterectomy

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06039566·Phase 3·Recruiting·Listed Sep 2023

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Modulating Escape Using Focused Ultrasound

for Anxiety Disorders

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT06273904·Recruiting·Listed Feb 2024

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Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

for Ventricular Tachycardia

Sites in Charleston +4 more locations

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06138873·Recruiting·Listed Nov 2023

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The Pediatric Anesthesia Quality Improvement Project

for Surgery

Sites in Charleston +36 more locations

Sponsor: The Society for Pediatric Anesthesia

Sex: All·Age: Up to 21

Code: NCT00674388·Recruiting·Listed May 2008

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Screening Women With Prior HPV for Anal Neoplasia

for HPV-related Lower Genital Tract Neoplasias

Sites in Charleston +2 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 35+

Code: NCT05217940·Recruiting·Listed Feb 2022

Apply to this trial

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

Sites in Charleston, Greenville +54 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting·Listed Feb 2013

Apply to this trial

Pulmonary Hemodynamics During Exercise - Research Network

for Pulmonary Circulation Diseases

Sites in Charleston +7 more locations

Sponsor: Medical University of Graz

Sex: All·Age: 18+

Code: NCT03954574·Recruiting·Listed May 2019

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Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

for Coronary Artery Disease

1 location in Charleston

Sponsor: Semmelweis University

Sex: All·Age: 18+

Code: NCT07016477·Recruiting·Listed Jun 2025

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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

Sites in Charleston +26 more locations

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting·Listed Sep 2022

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A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

for Inflammatory Bowel Disease

Sites in Charleston +1 more location

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT05579392·Recruiting·Listed Oct 2022

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Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06157840·Recruiting·Listed Dec 2023

Apply to this trial

A Pilot Study of a Remote ADHD Monitoring Program

for Attention-deficit/Hyperactivity Disorder

Sites in Charleston +1 more location

Sponsor: IDeA States Pediatric Clinical Trials Network

Sex: All·Age: 5 - 11·Accepts healthy volunteers

Code: NCT06743425·Recruiting·Listed Dec 2024

Apply to this trial

Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

for Post-Traumatic Stress Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 7 - 18

Code: NCT06332209·Recruiting·Listed Mar 2024

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

Sites in Charleston +50 more locations

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial