As of September 2026, 678 paid clinical trials are recruiting in Charleston, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charleston offers studies at sites including Medical University of South Carolina for conditions such as Stroke, Heart Failure, Depression, Cardiovascular Diseases. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Charleston, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Medical University of South Carolina | Depression, Heart Failure, Parkinson Disease | 372 |
| Medical University of South Carolina (MUSC) | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 27 |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Stroke, Depression, PTSD | 22 |
| Ralph H Johnson VA Medical Center | Stage IV Lung Cancer AJCC v8, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 11 |
| MUSC | Heart Failure, Cardiovascular Diseases, Focal Epilepsy | 7 |
| Medical University of South Carolina Hollings Cancer Center | Brain Metastases, Cancer (With CNS Involvement), Locally Advanced Pancreatic Adenocarcinoma | 7 |
| MUSC Hollings Cancer Center | Advanced Renal Cell Carcinoma (RCC), Advanced Solid Tumor, Cachexia | 6 |
| Ralph H. Johnson VA Health Care System | Adjustment Disorders, Alzheimer Disease, Alzheimer's Disease (AD) | 5 |
| GSK Investigational Site | Asthma, Chickenpox, Hypereosinophilic Syndrome | 4 |
| Hollings Cancer Center at Medical University of South Carolina | B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Locally Advanced Pancreatic Adenocarcinoma | 4 |
| Medical University of South Carolina University Hospital | Intracerebral Hemorrhage, Ischemic Stroke, Atrial Fibrillation | 4 |
| Bon Secours Saint Francis Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 3 |
| Hollings Cancer Center | Acute Myeloid Leukemia, Breast Cancer, Chronic Myelomonocytic Leukemia | 3 |
| Lowcountry Lung and Critical Care, PA | Idiopathic Hypersomnia, Idiopathic Pulmonary Fibrosis (IPF), OSA | 3 |
| MUSC Charleston | Arteriovenous Fistula, Catheter Complications, Catheter Dysfunction | 3 |
| Medical University South Carolina | Knee Arthroplasty, Total, Lower Respiratory Tract Infection, Myasthenia Gravis | 3 |
| Medical University of South Carolina Children's Hospital | Focal Segmental Glomerulosclerosis, Rheumatic Joint Disease | 3 |
| Ralph H. Johnson VA Medical Center | Alzheimers Disease, Fatigue, Prostate Cancer | 3 |
| University of South Carolina | Alpha1-Antitrypsin Deficiency, Growth Hormone Deficiency, Lupus Nephritis | 3 |
| Charleston Neuroscience Institute | NAION( Non-arteritic Anterior Ischemic Optic Neuropathy), Neovascular Age-related Macular Degeneration, Open Angle Glaucoma (OAG) | 3 |
| 30 Bee Street | Depression, Post Stroke Pain | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Charleston Neuroscience Institute, LLC (Charleston) | Macular Edema Secondary to Inflammation | 2 |
| Charleston VA Healthcare System | Chronic Pain, Post Traumatic Stress Disorder, Post Traumatic Stress Disorder (PTSD) | 2 |
Recruiting trials in Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 678 recruiting clinical trials in Charleston, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Charleston include Stroke (15), Heart Failure (14), Depression (13), Cardiovascular Diseases (9), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Charleston include Medical University of South Carolina, Medical University of South Carolina (MUSC), Ralph H. Johnson VA Medical Center, Charleston, SC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Charleston are Cancer & tumors (153), Neurology & pain (58), Mental health & behavior (57). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.