Paid Clinical Trials in Charleston, SC

As of July 2026, 683 paid clinical trials are recruiting in Charleston, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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608 clinical trials

Biologics in Chronic Rhinosinusitis With Nasal Polyposis

for Chronic Sinusitis

Sites in Charleston +1 more location

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06824649·Phase 4·Recruiting·Listed Feb 2025

Apply to this trial

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Charleston +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

Apply to this trial

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Charleston +16 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

Efficacy of Intramuscular Steroid Injection for Chronic Cough.

for Chronic Cough (CC)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06634823·EARLY_Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

Healing, Equity, Advocacy and Respect for Mamas

for Postpartum Complication

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 16 - 49

Code: NCT06273436·Recruiting·Listed Feb 2024

Apply to this trial

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Charleston, Bluffton +471 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

Apply to this trial

Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes

for Smoking Prevention and Control

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05896033·Recruiting·Listed Jun 2023

Apply to this trial

RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

for Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05977439·Recruiting·Listed Aug 2023

Apply to this trial

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

Sites in Charleston, Columbia +31 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

Apply to this trial

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Charleston, Columbia +209 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Sites in Charleston +2 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT02074839·Phase 1·Recruiting·Listed Feb 2014

Apply to this trial

Switch or Quit R01

for Cigarette Smoking

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06373679·Recruiting·Listed Apr 2024

Apply to this trial

QL vs LAI for Palatoplasty

for Post-operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 18

Code: NCT06420336·Recruiting·Listed May 2024

Apply to this trial

Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury

for Spinal Cord Injuries

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05321017·Recruiting·Listed Apr 2022

Apply to this trial

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Charleston, Columbia +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

Apply to this trial

Atomoxetine and Executive Function in PTSD

for Posttraumatic Stress Disorder With Attention Defic

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06573970·Phase 4·Recruiting·Listed Aug 2024

Apply to this trial

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Charleston +79 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

Apply to this trial

Young Adult Tobacco/Nicotine and Cannabis Co-use

for Tobacco Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT06239350·Recruiting·Listed Feb 2024

Apply to this trial

Telerehabilitation In The Home After Stroke

for Stroke

Sites in Charleston +26 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 80

Code: NCT06682429·Recruiting·Listed Nov 2024

Apply to this trial

The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Charleston +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

Apply to this trial

Prediction Augmented Screening Initiative

for Lung Cancer

Sites in Charleston +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT06538636·Recruiting·Listed Aug 2024

Apply to this trial

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Charleston, Columbia +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Epilepsy Journey-An Executive Functioning Intervention for Teens With Epilepsy

for Epilepsy in Children

Sites in Charleston +2 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 13 - 17

Code: NCT06608966·Recruiting·Listed Sep 2024

Apply to this trial

Induction in the Dark

for Anesthesia Induction

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 6

Code: NCT06144177·Phase 4·Recruiting·Listed Nov 2023

Apply to this trial

CBD for Breast Cancer Primary Tumors

for Breast Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06148038·Phase 1·Recruiting·Listed Nov 2023

Apply to this trial

Tele-PCIT for Healthy Relationships in Families At-Risk

for Disruptive Behavior

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 7

Code: NCT07225010·Recruiting·Listed Nov 2025

Apply to this trial

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

Sites in Charleston +21 more locations

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting·Listed Feb 2022

Apply to this trial

Emotional Recovery Post-Stroke

for Stroke

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT06782321·Recruiting·Listed Jan 2025

Apply to this trial

Examining Whether Project Support Works

for Parent-Child Relations

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 13

Code: NCT06963554·Recruiting·Listed May 2025

Apply to this trial

Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

for Neuroblastoma

Sites in Charleston +19 more locations

Sponsor: Giselle Sholler

Sex: All·Age: Up to 22

Code: NCT02559778·Phase 2·Recruiting·Listed Sep 2015

Apply to this trial

Social Functioning in Opioid Use Disorder

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07044466·Recruiting·Listed Jul 2025

Apply to this trial

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Charleston +59 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

Apply to this trial

E-cigarette Cessation in Adults Who Co-use Cannabis

for Nicotine Dependence

Sites in Charleston, Lancaster & Pickens

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06688539·Phase 4·Recruiting·Listed Nov 2024

Apply to this trial

The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

for Head and Neck Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05811936·Recruiting·Listed Apr 2023

Apply to this trial

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

for Substance Use Disorders

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 15 - 30·Accepts healthy volunteers

Code: NCT05816083·Recruiting·Listed Apr 2023

Apply to this trial

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

for Medulloblastoma

Sites in Charleston +22 more locations

Sponsor: Giselle Sholler

Sex: All·Age: Up to 21

Code: NCT04696029·Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

for Inflammatory Bowel Disease

Sites in Charleston +1 more location

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT05579392·Recruiting·Listed Oct 2022

Apply to this trial

ERP to Improve Functioning in Veterans With OCD

for Obsessive Compulsive Disorder (OCD)

Sites in Charleston +18 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05240924·Recruiting·Listed Feb 2022

Apply to this trial

Methadone in THA for Post-op Pain and Opioid Reduction

for Post Operative Pain

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT07227064·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

for Brain Metastases

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07227610·Phase 2·Recruiting·Listed Nov 2025

Apply to this trial