Feasibility of HISA During TURBT for NMIBC
for Bladder Cancer
1 location in Charleston
Sponsor: CAMC Health System
Sex: All·Age: 18 - 89
Code: NCT07817173·Not Yet Recruiting·Listed Sep 14, 2026
Paid Clinical Trials in Charleston, WV
As of September 2026, 65 paid clinical trials are recruiting in Charleston, West Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charleston offers studies at sites including West Virginia University Charleston Division for conditions such as Coronary Artery Disease, Anatomic Stage III Breast Cancer AJCC v8, Gastroesophageal Junction Adenocarcinoma, Lumbar Spinal Stenosis. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Charleston
Trials by drug in Charleston
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Newly added in Charleston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
for Overweight
Drug: Orforglipron
Sites in Charleston, Kingwood +77 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07794579·Phase 3·Not Yet Recruiting·Listed Aug 31, 2026
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
for Healthy Adult Participants
Sites in Charleston +50 more locations
Sponsor: Ecotera Health LLC
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07775495·Not Yet Recruiting·Listed Aug 20, 2026
65 clinical trials
Get a weekly email when new trials open in Charleston, WV.
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
for Macular Degeneration
Sites in Charleston +65 more locations
Sponsor: EyeBiotech Ltd.
Sex: All·Age: 50+
Code: NCT07440225·Phase 2, Phase 3·Recruiting·Listed Feb 2026
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
for HIV Infections
Sites in Charleston +37 more locations
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT07473778·Recruiting·Listed Mar 2026
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
for Non-Small Cell Lung Cancer (NSCLC)
Drug: Pumitamig
Sites in Charleston +40 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07361510·Phase 3·Recruiting·Listed Jan 2026
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
for CRC (Colorectal Cancer)
Drug: Bevacizumab
Sites in Charleston, Morgantown +73 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07284849·Phase 3·Recruiting·Listed Dec 2025
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
for Metabolic Dysfunction-Associated Steatotic Liver Disease
Sites in Charleston +141 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07165028·Phase 3·Recruiting·Listed Sep 2025
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
for Diabetes Mellitus, Type 2
Sites in Charleston +122 more locations
Sponsor: Cleerly, Inc.
Sex: All·Age: 55+·Accepts healthy volunteers
Code: NCT06112418·Recruiting·Listed Nov 2023
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Charleston, South Charleston +2386 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
for Metastatic Colorectal Cancer (CRC)
Drug: Bevacizumab
Sites in Charleston +101 more locations
Sponsor: Summit Therapeutics
Sex: All·Age: 18+
Code: NCT07228832·Phase 3·Recruiting·Listed Nov 2025
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
for Coronary Arterial Disease (CAD)
Sites in Charleston +45 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: 18+
Code: NCT06959524·Recruiting·Listed May 2025
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO
for Neovascular Age-Related Macular Degeneration (NVAMD)
Sites in Charleston +54 more locations
Sponsor: EyeBiotech Ltd.
Sex: All·Age: 18+
Code: NCT07205887·Phase 2·Recruiting·Listed Oct 2025
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
for Stroke
Sites in Charleston +30 more locations
Sponsor: W.L.Gore & Associates
Sex: All·Age: 18 - 70
Code: NCT03821129·Recruiting·Listed Jan 2019
ELEVATE-HFpEF Clinical Study
for Heart Failure With Preserved Ejection Fraction (HFpEF)
Sites in Charleston +25 more locations
Sponsor: Medtronic Cardiac Rhythm and Heart Failure
Sex: All·Age: 40+
Code: NCT06678841·Recruiting·Listed Nov 2024
SELUTION 4 De Novo Small Vessel IDE Trial
for Coronary Artery Disease
Sites in Charleston +63 more locations
Sponsor: M.A. Med Alliance S.A.
Sex: All·Age: 18+
Code: NCT05946629·Recruiting·Listed Jul 2023
Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
for Chronic Granulomatous Disease (CGD)
Sites in Charleston +49 more locations
Sponsor: Ensoma
Sex: All·Age: All ages
Code: NCT06605378·Recruiting·Listed Sep 2024
SuperSaturated Oxygen Comprehensive Observational Registry
for STEMI - ST Elevation Myocardial Infarction
Sites in Charleston, Huntington +23 more locations
Sponsor: TherOx
Sex: All·Age: 18 - 80
Code: NCT06438315·Recruiting·Listed May 2024
Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis
for AAA - Abdominal Aortic Aneurysm
Sites in Charleston +55 more locations
Sponsor: W.L.Gore & Associates
Sex: All·Age: 18+
Code: NCT06218875·Recruiting·Listed Jan 2024
Caris Biorepository Research Protocol
for Cancer
Sites in Charleston +37 more locations
Sponsor: Caris Science, Inc.
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT01499394·Recruiting·Listed Dec 2011
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
for Macular Edema
Sites in Charleston +37 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT06962839·Phase 2·Recruiting·Listed May 2025
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
for Degenerative Disc Disease
Sites in Charleston +18 more locations
Sponsor: VIVEX Biologics, Inc.
Sex: All·Age: 22 - 85
Code: NCT06778447·Recruiting·Listed Jan 2025
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
for Pulmonary Embolism
Sites in Charleston +22 more locations
Sponsor: Thrombolex, Inc.
Sex: All·Age: All ages
Code: NCT06433011·Recruiting·Listed May 2024
BoxX-NoAF Clinical Trial
for Post Operative Atrial Fibrillation
Sites in Charleston +23 more locations
Sponsor: AtriCure, Inc.
Sex: All·Age: 65+·Accepts healthy volunteers
Code: NCT06989775·Recruiting·Listed May 2025
Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
for Ovarian Cancer
Sites in Charleston, Morgantown +8 more locations
Sponsor: NX Development Corp
Sex: Female·Age: 18+
Code: NCT05804370·Phase 3·Recruiting·Listed Apr 2023
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions
for Coronary Disease
Sites in Charleston +1 more location
Sponsor: Teleflex
Sex: All·Age: 18 - 80
Code: NCT07258290·Recruiting·Listed Dec 2025
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
for Coronary Artery Disease
Sites in Charleston +9 more locations
Sponsor: Teleflex
Sex: All·Age: 18+
Code: NCT06779630·Recruiting·Listed Jan 2025
Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device
for Degenerative Conditions of the Lumbar Spine
Sites in Charleston +5 more locations
Sponsor: Spinal Simplicity LLC
Sex: All·Age: 18+
Code: NCT06355791·Recruiting·Listed Apr 2024
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Charleston, Parkersburg +923 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Charleston +627 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
for Advanced Endometrial Carcinoma
Drug: Bevacizumab
Sites in Charleston, Parkersburg +261 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
for Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Drug: Bevacizumab
Sites in Charleston +325 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04181060·Phase 3·Recruiting·Listed Nov 2019
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Charleston, Morgantown +532 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Charleston, Parkersburg +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in Charleston, Parkersburg +401 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Charleston, Morgantown +438 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
for Locally Advanced Cervical Adenocarcinoma
Sites in Charleston, Parkersburg +318 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in Charleston, Huntington +380 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma
for Classic Follicular Lymphoma
Drug: Mosunetuzumab
Sites in Charleston +256 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06337318·Phase 3·Recruiting·Listed Mar 2024
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Charleston, Huntington +425 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Charleston, Huntington +381 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
for Renal Pelvis and Ureter Urothelial Carcinoma
Drug: Durvalumab
Sites in Charleston +151 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04628767·Phase 2, Phase 3·Recruiting·Listed Nov 2020
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
for Ovarian Carcinoma
Sites in Charleston, Parkersburg +479 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 35 - 50
Code: NCT04251052·Recruiting·Listed Jan 2020
Top Research Study Locations in Charleston
Researchers run research studies in Charleston, WV at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| West Virginia University Charleston Division | Anatomic Stage III Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Acute Myeloid Leukemia | 28 |
| Charleston Area Medical Center | Coronary Artery Disease, AMI, Acute Coronary Syndrome | 8 |
| Retina Consultants, PLLC | Age-Related Macular Degeneration, Branch Retinal Vein Occlusion (BRVO), Choroidal Neovascularization | 3 |
| Charleston Area Medical Center (CAMC) | Non-Small Cell Lung Cancer (NSCLC), PFO - Patent Foramen Ovale, Stroke | 2 |
| CAMC | Coronary Artery Disease | 1 |
| CAMC Clinical Trials | Cancer, Early Detection of Cancer, Minimal Residual Disease | 1 |
| CAMC Clinical Trials Center | Type B Aortic Dissection | 1 |
| CAMC Health Education and Research Institute | AKI (Acute Kidney Injury) Due to Trauma | 1 |
| CAMC Health Education and Research Institute Inc | Metabolic Dysfunction-Associated Steatotic Liver Disease | 1 |
| CAMC Health and Education and Research Institute, Inc | AAA - Abdominal Aortic Aneurysm | 1 |
| CAMC Institute for Academic Medicine | Obesity, Abdominal, Overweight, Prediabetic State | 1 |
| CAMC Institute for Academic Medicine - Cancer Research Center | Ovarian Cancer | 1 |
| CAMC Memorial | Anesthesia, Interventional Radiology, Sedation and Analgesia | 1 |
| Charleston Area Medical Center (CAMC) Memorial Hospital | Heart Failure With Preserved Ejection Fraction (HFpEF) | 1 |
| Charleston Area Medical Center Memorial Hospital | Bladder (Urothelial, Transitional Cell) Cancer Resectable (Pre-Cystectomy), Bladder Cancer, Bladder Cancer (BC) | 1 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC) | 1 |
| Day Surgery Center | Lumbar Spinal Stenosis | 1 |
| Decentralized / At-Home Participation (U.S.) | Healthy Adult Participants | 1 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
| Spine & Nerve Center of the Virginias | Degenerative Conditions of the Lumbar Spine, Lumbar Spinal Stenosis, Spondylolisthesis | 1 |
| The Saint Francis Hospital Center for Pain Relief | Lumbar Spinal Stenosis | 1 |
| The Spine and Nerve Center C/O Clinical Research | Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain | 1 |
| The Spine and Nerve Center of Saint Francis Hospital | Chronic Pain, Neuropathic Pain, Pain | 1 |
| Vandalia Health Charleston Area Medical Center | CRC (Colorectal Cancer) | 1 |
| WVUM/Thomas Hospitals (Saint Francis Hospital) Spine and Nerve Center | Chronic Low Back Pain (CLBP) | 1 |
Active & Upcoming Studies in Charleston (2026)
Recruiting trials in Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (35 active studies)
Cardiovascular (6 active studies)
Neurology & pain (5 active studies)
Eye & vision (3 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO · Phase 2 · EyeBiotech Ltd.
Diabetes & metabolic (2 active studies)
- A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity · Phase 3 · Eli Lilly and Company
- A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events · Cleerly, Inc.
HIV / STI (1 active study)
Common conditions studied in Charleston
- Coronary Artery Disease (3 active studies)
- Anatomic Stage III Breast Cancer AJCC v8 (2 active studies)
- Gastroesophageal Junction Adenocarcinoma (2 active studies)
- Lumbar Spinal Stenosis (2 active studies)
- Pain (2 active studies)
- Recurrent Endometrial Carcinoma (2 active studies)
Leading research sponsors in Charleston
- National Cancer Institute (NCI)
- Children's Oncology Group
- CAMC Health System
- Alliance for Clinical Trials in Oncology
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Charleston?
There are approximately 65 recruiting clinical trials in Charleston, West Virginia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Charleston pay participants?
Most recruiting trials in Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Charleston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Charleston?
The most common conditions under active study in Charleston include Coronary Artery Disease (3), Anatomic Stage III Breast Cancer AJCC v8 (2), Gastroesophageal Junction Adenocarcinoma (2), Lumbar Spinal Stenosis (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Charleston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Charleston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Charleston?
Recruiting research sites in Charleston include West Virginia University Charleston Division, Charleston Area Medical Center, Retina Consultants, PLLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Charleston right now?
The largest active categories in Charleston are Cancer & tumors (35), Cardiovascular (6), Neurology & pain (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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