Paid Clinical Trials in Charleston, WV
As of July 2026, 62 paid clinical trials are recruiting in Charleston, West Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charleston offers studies at sites including West Virginia University Charleston Division for conditions such as Coronary Artery Disease, Pain, Anatomic Stage III Breast Cancer AJCC v8, Gastroesophageal Junction Adenocarcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Charleston
Trials by drug in Charleston
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61 clinical trials
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
SELUTION 4 De Novo Small Vessel IDE Trial
ELEVATE-HFpEF Clinical Study
SuperSaturated Oxygen Comprehensive Observational Registry
Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis
Caris Biorepository Research Protocol
Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
BoxX-NoAF Clinical Trial
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device
Prospective IR-led Sedation Feasibility
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
Top Research Study Locations in Charleston
Researchers run research studies in Charleston, WV at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| West Virginia University Charleston Division | Anatomic Stage III Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Acute Myeloid Leukemia | 29 |
| Charleston Area Medical Center | Coronary Artery Disease, AMI, Acute Coronary Syndrome | 8 |
| CAMC | Coronary Artery Disease | 1 |
| CAMC Clinical Trials | Cancer, Early Detection of Cancer, Minimal Residual Disease | 1 |
| CAMC Clinical Trials Center | Type B Aortic Dissection | 1 |
| CAMC Health Education and Research Institute | AKI (Acute Kidney Injury) Due to Trauma | 1 |
| CAMC Health Education and Research Institute Inc | Metabolic Dysfunction-Associated Steatotic Liver Disease | 1 |
| CAMC Health and Education and Research Institute, Inc | AAA - Abdominal Aortic Aneurysm | 1 |
| CAMC Institute for Academic Medicine - Cancer Research Center | Ovarian Cancer | 1 |
| CAMC Memorial | Anesthesia, Interventional Radiology, Sedation and Analgesia | 1 |
| Charleston Area Medical Center (CAMC) | PFO - Patent Foramen Ovale, Stroke | 1 |
| Charleston Area Medical Center (CAMC) Memorial Hospital | Heart Failure With Preserved Ejection Fraction (HFpEF) | 1 |
| Charleston Area Medical Center Institute for Academic Medicine | Pain | 1 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC) | 1 |
| Day Surgery Center | Lumbar Spinal Stenosis | 1 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
| Local Institution - 0339 | Non-Small Cell Lung Cancer (NSCLC) | 1 |
| Retina Consultants, PLLC | Age-Related Macular Degeneration, Choroidal Neovascularization, Macular Degeneration | 1 |
| Spine & Nerve Center of the Virginias | Degenerative Conditions of the Lumbar Spine, Lumbar Spinal Stenosis, Spondylolisthesis | 1 |
| The Saint Francis Hospital Center for Pain Relief | Lumbar Spinal Stenosis | 1 |
| The Spine and Nerve Center C/O Clinical Research | Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain | 1 |
| The Spine and Nerve Center of Saint Francis Hospital | Chronic Pain, Neuropathic Pain, Pain | 1 |
| Vandalia Health Charleston Area Medical Center | CRC (Colorectal Cancer) | 1 |
| WVUM/Thomas Hospitals (Saint Francis Hospital) Spine and Nerve Center | Chronic Low Back Pain (CLBP) | 1 |
| West Virginia Health Right, Inc. | HIV Infections | 1 |
Active & Upcoming Studies in Charleston (2026)
Recruiting trials in Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (34 active studies)
- A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202) · Phase 3 · Bristol-Myers Squibb
- A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer · Phase 3 · Incyte Corporation
Neurology & pain (6 active studies)
Cardiovascular (6 active studies)
HIV / STI (1 active study)
Diabetes & metabolic (1 active study)
Eye & vision (1 active study)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Common conditions studied in Charleston
- Coronary Artery Disease (3 active studies)
- Pain (3 active studies)
- Anatomic Stage III Breast Cancer AJCC v8 (2 active studies)
- Gastroesophageal Junction Adenocarcinoma (2 active studies)
- Lumbar Spinal Stenosis (2 active studies)
- Recurrent Endometrial Carcinoma (2 active studies)
Leading research sponsors in Charleston
- National Cancer Institute (NCI)
- Children's Oncology Group
- CAMC Health System
- Alliance for Clinical Trials in Oncology
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Charleston?
There are approximately 62 recruiting clinical trials in Charleston, West Virginia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Charleston pay participants?
Most recruiting trials in Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Charleston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Charleston?
The most common conditions under active study in Charleston include Coronary Artery Disease (3), Pain (3), Anatomic Stage III Breast Cancer AJCC v8 (2), Gastroesophageal Junction Adenocarcinoma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Charleston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Charleston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Charleston?
Recruiting research sites in Charleston include West Virginia University Charleston Division, Charleston Area Medical Center, CAMC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Charleston right now?
The largest active categories in Charleston are Cancer & tumors (34), Neurology & pain (6), Cardiovascular (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.