Oncology Clinical Trials in Charlottesville, VA

As of August 2026, 114 paid clinical trials are recruiting for Oncology in Charlottesville, Virginia. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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114 clinical trials for Oncology

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Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Charlottesville +13 more locations

Sponsor: Debiopharm International SA

Sex: All·Age: 12+

Code: NCT04855656·Phase 1·Recruiting·Listed Apr 2021

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Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for Cholangiocarcinoma

Drug: Trametinib

Sites in Charlottesville +7 more locations

Sponsor: Genfit

Sex: All·Age: 18+

Code: NCT05874414·Phase 1, Phase 2·Recruiting·Listed May 2023

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

Sites in Charlottesville, Fairfax +16 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting·Listed Oct 2018

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A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

for Solid Tumor

Sites in Charlottesville, Fairfax +13 more locations

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06586957·Phase 1·Recruiting·Listed Sep 2024

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A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

Sites in Charlottesville, Fairfax +11 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for Prostate Cancer

Sites in Charlottesville +13 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT04729114·Phase 1·Recruiting·Listed Jan 2021

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A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

for Ovarian Cancer

Sites in Charlottesville +12 more locations

Sponsor: Compugen Ltd

Sex: Female·Age: 18+

Code: NCT06888921·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

Sites in Charlottesville +8 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting·Listed Nov 2021

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A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

for Colorectal Cancer

Sites in Charlottesville +8 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07659795·Phase 2·Recruiting·Listed Jun 2026

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A Study of BI 3810944 in Patients With Advanced Cancer

for Solid Tumours

Sites in Charlottesville +3 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07224425·Phase 1·Recruiting·Listed Nov 2025

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Study With [225Ac]Ac-FL-020 in mCRPC Participants

for Metastatic Castration-resistant Prostate Cancer

Sites in Charlottesville +4 more locations

Sponsor: Full-Life Technologies UK Limited

Sex: Male·Age: 18+

Code: NCT06492122·Phase 1·Recruiting·Listed Jul 2024

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A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

for Acute Myeloid Leukemia

Sites in Charlottesville +7 more locations

Sponsor: Chordia Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05732103·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

for Glioblastoma Multiforme

Drug: Bevacizumab

1 location in Charlottesville

Sponsor: NaviFUS Corporation

Sex: All·Age: 18+

Code: NCT06329570·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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A Feasibility Study of Biometric Measurements Via Wearable Smart Watch Technology for Evaluation of Vasomotor Symptoms in Patients Treated With Androgen Deprivation Therapy for Prostate Cancer (Prostate 007)

for Prostate Cancer

1 location in Charlottesville

Sponsor: University of Virginia

Sex: Male·Age: 18+

Code: NCT07535541·Recruiting·Listed Apr 2026

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HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)

for Breast Cancer

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT07441889·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Charlottesville, Fishersville +1098 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in Charlottesville, Richmond +653 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

Sites in Charlottesville, Richmond +276 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Charlottesville, Richmond +479 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

Sites in Charlottesville, Richmond +328 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in Charlottesville, Richmond +429 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Sites in Charlottesville, Fairfax +204 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting·Listed Sep 2022

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Charlottesville, Richmond +214 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting·Listed Mar 2024

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Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Charlottesville, Fairfax +167 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting·Listed Sep 2022

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Charlottesville, Richmond +115 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Charlottesville, Richmond +255 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024

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Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for Malignant Female Reproductive System Neoplasm

Sites in Charlottesville, Fairfax +176 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

Sites in Charlottesville, Richmond +185 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting·Listed May 2019

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Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements

Sites in Charlottesville, Richmond +59 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06649812·Phase 2·Recruiting·Listed Oct 2024

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in Charlottesville, Richmond +167 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Charlottesville, Richmond +225 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

Sites in Charlottesville, Richmond +73 more locations

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting·Listed Dec 2022

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Phase Ib Study of CD33 FPBMC in Patients With MRD+ AML or MDS

for Acute Myeloid Leukemia

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT07270978·Phase 1·Recruiting·Listed Dec 2025

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Charlottesville, Richmond +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Charlottesville, Richmond +200 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Charlottesville, Portsmouth +152 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

for Colorectal Polyp

Sites in Charlottesville +17 more locations

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 65 - 82

Code: NCT05612347·Recruiting·Listed Nov 2022

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in Charlottesville, Richmond +40 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Sites in Charlottesville, Norfolk +34 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 25

Code: NCT07022678·Phase 3·Recruiting·Listed Jun 2025

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A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for Glioblastoma

Sites in Charlottesville +20 more locations

Sponsor: Global Coalition for Adaptive Research

Sex: All·Age: 18+

Code: NCT03970447·Phase 2, Phase 3·Recruiting·Listed May 2019

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Conditions in Oncology (Charlottesville, VA)

Non-small cell lung cancer (NSCLC)· 16 Solid tumor· 15 Acute myeloid leukemia (AML)· 11 Breast cancer· 10 Prostate cancer· 9 Ovarian cancer· 9 Metastatic prostate cancer· 8 Endometrial cancer· 7 Myelodysplastic syndromes (MDS)· 6 Colorectal cancer· 5 Pancreatic cancer· 5 Melanoma· 5 Cancer (any)· 5 Cervical cancer· 4 Glioblastoma· 4 Leukemia (other)· 4 Non-Hodgkin lymphoma· 4 Diffuse large B-cell lymphoma (DLBCL)· 4 Hematologic malignancy· 4 Lung cancer· 3 Biliary tract cancer· 3 Bladder cancer· 3 Myelofibrosis· 3 Mantle cell lymphoma· 3 Head and neck cancer· 3 Triple-negative breast cancer· 2 Small cell lung cancer· 2 Gastric cancer· 2 Fallopian tube cancer· 2 Glioma· 2 Multiple myeloma· 2 Myeloproliferative neoplasm· 2 Neuroendocrine tumors· 2 Metastatic breast cancer· 1 HER2-negative breast cancer· 1 Gastroesophageal junction cancer· 1 Liver cancer· 1 Kidney cancer· 1 Brain cancer· 1 Chronic lymphocytic leukemia (CLL)· 1 Acute lymphoblastic leukemia· 1 Hodgkin lymphoma· 1 Follicular lymphoma· 1 Marginal zone lymphoma· 1 Small lymphocytic lymphoma· 1 Thyroid cancer· 1 Osteosarcoma· 1 Ewing sarcoma· 1 Rhabdomyosarcoma· 1 Neuroblastoma· 1