Paid Clinical Trials in Charlottesville, VA
As of August 2026, 526 paid clinical trials are recruiting in Charlottesville, Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charlottesville offers studies at sites including University of Virginia for conditions such as Acute Myeloid Leukemia, Heart Failure, Breast Cancer, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Charlottesville
Trials by drug in Charlottesville
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Newly added in Charlottesville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
471 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Brenipatide in Participants With Opioid Use Disorder
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
A Study of Buntanetap in Participants With PD
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study of Dotinurad Versus Allopurinol in Participants With Gout
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
Top Research Study Locations in Charlottesville
Researchers run research studies in Charlottesville, VA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Virginia | Breast Cancer, Cystic Fibrosis, Acute Myeloid Leukemia | 183 |
| University of Virginia Cancer Center | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 84 |
| University of Virginia Health System | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 50 |
| University of Virginia Medical Center | Bone Density, Bone Strength, FHA (Functional Hypothalamic Amenorrhea) | 22 |
| University of Virginia Comprehensive Cancer Center | AML, AML With Mutated NPM1, Acute Leukemia | 12 |
| UVA Health | Anesthesia, Anesthesia Awareness, Anesthesia Complication | 8 |
| Charlottesville Medical Research | Osteoarthritis, Gout, Hypercholesterolemia | 7 |
| UVA Comprehensive Cancer Center | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 5 |
| UVA Medical Center | Ischemic Stroke, Stroke, Atrial Fibrillation | 5 |
| University of Virginia Center for Diabetes Technology | Type 1 Diabetes, Type 1 Diabetes (T1D), Type 1 Diabetes Mellitis | 5 |
| University of Virginia School of Medicine | Acute Myeloid Leukemia (AML), Drug Resistant Epilepsy, Epilepsy | 5 |
| Pediatric Research of Charlottesville, LLC | Acute Treatment of Migraine, Measles, Measles-Mumps-Rubella+Chickenpox Vaccine | 5 |
| UVA Health University Medical Center | AV Block, Bradycardia, Cardiac Rhythm Disorder | 4 |
| University of Virginia (UVA) | Atrial Flutter Typical, Complex Congenital Heart Defect, Coronary Artery Disease Progression | 4 |
| University of Virginia Health | Colorectal Adenoma, Colorectal Cancer, Colorectal Neoplasms | 4 |
| UVA Children's Hospital | Duchenne Muscular Dystrophy, Failed or Difficult Intubation, Sequela, Hypoplastic Left Heart Syndrome (HLHS) | 3 |
| Charlottesville Medical Research Center, LLC | Chronic Idiopathic Constipation (CIC), Healthy Adults | 2 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC), Non-Small Cell Lung Cancer | 2 |
| Clinical Trial Site | Hypophosphatasia, Transthyretin Amyloidosis With Cardiomyopathy | 2 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Influenza, Human+COVID-19 | 2 |
| Pediatric Associates of Charlottesville, PLC (Private Pediatric Practice) | Acute Treatment of Migraine, Pediatric Migraine | 2 |
| Pediatric Research of Charlottesville, LLC (Regulatory Only) | Acute Treatment of Migraine, Pediatric Migraine | 2 |
| Snyder Building 480 Ray C. Hunt Drive | E-Cig Use, Idiopathic Pulmonary Fibrosis | 2 |
| UVA Health Cancer Care Pantops | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 2 |
| UVA Health Systems | Clostridia Difficile Colitis, Clostridioides Difficile Infection, Clostridium Difficile Diarrhea | 2 |
Active & Upcoming Studies in Charlottesville (2026)
Recruiting trials in Charlottesville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (183 active studies)
- Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma · Phase 2 · National Cancer Institute (NCI)
- Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer · IMGT Co., Ltd.
Cardiovascular (37 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis · Phase 3 · Duke University
Neurology & pain (35 active studies)
- A System to Help With Freezing of Gait in Parkinson's Patients · Barron Associates, Inc.
- Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE) · Phase 3 · Ambros Therapeutics, Inc.
Diabetes & metabolic (29 active studies)
- The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED) · Phase 3 · University of Virginia
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
Mental health & behavior (8 active studies)
- VergeRx for Smokers Not Ready to Quit · University of Virginia
- Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design · University of Virginia
Vaccines (4 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
Pediatric (4 active studies)
- Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy · Phase 2 · University of Virginia
- Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients · Phase 3 · Octapharma
Eye & vision (1 active study)
Common conditions studied in Charlottesville
- Acute Myeloid Leukemia (11 active studies)
- Heart Failure (8 active studies)
- Breast Cancer (7 active studies)
- Endometrial Cancer (7 active studies)
- Atrial Fibrillation (6 active studies)
- Ovarian Cancer (6 active studies)
Leading research sponsors in Charlottesville
- University of Virginia
- National Cancer Institute (NCI)
- Children's Oncology Group
- Merck Sharp & Dohme LLC
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Charlottesville?
There are approximately 526 recruiting clinical trials in Charlottesville, Virginia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Charlottesville pay participants?
Most recruiting trials in Charlottesville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Charlottesville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Charlottesville?
The most common conditions under active study in Charlottesville include Acute Myeloid Leukemia (11), Heart Failure (8), Breast Cancer (7), Endometrial Cancer (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Charlottesville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charlottesville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Charlottesville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Charlottesville?
Recruiting research sites in Charlottesville include University of Virginia, University of Virginia Cancer Center, University of Virginia Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Charlottesville right now?
The largest active categories in Charlottesville are Cancer & tumors (183), Cardiovascular (37), Neurology & pain (35). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.