Paid Clinical Trials in Charlottesville, VA

As of September 2026, 525 paid clinical trials are recruiting in Charlottesville, Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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469 clinical trials

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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

for Cervical Deformity

Sites in Charlottesville +12 more locations

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04194996·Recruiting·Listed Dec 2019

Apply to this trial

Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

for Kidney Transplant

Sites in Charlottesville +14 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT05917522·Phase 2·Recruiting·Listed Jun 2023

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Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

for Adult Spinal Deformity

Sites in Charlottesville +7 more locations

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04888104·Recruiting·Listed May 2021

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Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

for Cryoglobulinemic Vasculitis (CV)

Sites in Charlottesville +1 more location

Sponsor: Peter Merkel

Sex: All·Age: 5+

Code: NCT03004326·Recruiting·Listed Dec 2016

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

Sites in Charlottesville +34 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting·Listed Aug 2019

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A Study of a Test for Postpartum Depression at Home

for Postpartum Depression (PPD)

1 location in Charlottesville

Sponsor: University of Virginia

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07186309·Recruiting·Listed Sep 2025

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HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma

for Squamous Cell Carcinoma of the Oropharynx

Sites in Charlottesville, Richmond +3 more locations

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT05962242·Phase 2·Recruiting·Listed Jul 2023

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Left vs Left Randomized Clinical Trial

for Heart Failure

Sites in Charlottesville, Richmond +55 more locations

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting·Listed Dec 2022

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Maternal Newborn Health Registry

for Pregnancy Outcome Trends in Low-resource Geographic Areas

Sites in Charlottesville +7 more locations

Sponsor: NICHD Global Network for Women's and Children's Health

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01073475·Recruiting·Listed Feb 2010

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Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCL

for PTCL

Sites in Charlottesville +5 more locations

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT04747236·Phase 2·Recruiting·Listed Feb 2021

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HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

for HFpEF - Heart Failure With Preserved Ejection Fraction

Sites in Charlottesville +2 more locations

Sponsor: University of Nebraska

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05784753·Recruiting·Listed Mar 2023

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

Sites in Charlottesville +40 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting·Listed Mar 2024

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Artificial Pancreas Technology to Reduce Glycemic Variability and Improve Cardiovascular Health in Type 1 Diabetes

for Type 1 Diabetes

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 40

Code: NCT05653518·Recruiting·Listed Dec 2022

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Recombinant vWF Concentrate and ECMO

for Bleeding Disorder

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT06118372·Phase 1·Recruiting·Listed Nov 2023

Apply to this trial

AWARE: Management of ADHD in Autism Spectrum Disorder

for ADHD

Sites in Charlottesville +9 more locations

Sponsor: Daniel Coury

Sex: All·Age: 4 - 17

Code: NCT05916339·Phase 4·Recruiting·Listed Jun 2023

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Clinical Validation of a Predictive Test for Postpartum Depression

for Postpartum Depression (PPD)

Sites in Charlottesville & Falls Church

Sponsor: University of Virginia

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06831968·Recruiting·Listed Feb 2025

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Oxytocin Effects on Bone in Children With Autism Spectrum Disorder

for Autism Spectrum Disorder

Sites in Charlottesville +1 more location

Sponsor: Elizabeth Austen Lawson

Sex: All·Age: 6 - 18

Code: NCT05754073·Phase 2·Recruiting·Listed Mar 2023

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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in Charlottesville, Richmond +128 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

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The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis

for Autoimmune Encephalitis

Drug: Inebilizumab

Sites in Charlottesville +34 more locations

Sponsor: University of Utah

Sex: All·Age: 12+

Code: NCT04372615·Phase 2·Recruiting·Listed May 2020

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Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study

for Intubation Complication

Sites in Charlottesville +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 19

Code: NCT06085326·Recruiting·Listed Oct 2023

Apply to this trial

MYTHS - MYocarditis THerapy With Steroids

for Myocarditis Acute

Sites in Charlottesville, Richmond +2 more locations

Sponsor: Niguarda Hospital

Sex: All·Age: 18 - 69

Code: NCT05150704·Phase 3·Recruiting·Listed Dec 2021

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Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

for Heart Failure, Systolic

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT06009276·Recruiting·Listed Aug 2023

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Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

for Acute Myocardial Infarction

Sites in Charlottesville +12 more locations

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT05701358·Recruiting·Listed Jan 2023

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Genetic Information Assistant in Telegenetics

for Gene Mutation-Related Cancer

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06089421·Recruiting·Listed Oct 2023

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Excision of Lymph Node Trial (EXCILYNT) (Mel69)

for Melanoma

Sites in Charlottesville +6 more locations

Sponsor: Craig L Slingluff, Jr

Sex: All·Age: 18+

Code: NCT05839912·Recruiting·Listed May 2023

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Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification

for Type 2 Diabetes

Sites in Charlottesville +1 more location

Sponsor: Chiara Fabris, PhD

Sex: All·Age: 30 - 80

Code: NCT05766735·Recruiting·Listed Mar 2023

Apply to this trial

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

Sites in Charlottesville, Henrico +50 more locations

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting·Listed Apr 2012

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PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction

for Heart Failure With Reduced Ejection Fraction

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 65+

Code: NCT05609097·Recruiting·Listed Nov 2022

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Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

for Breast Cancer

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT05288777·Phase 2, Phase 3·Recruiting·Listed Mar 2022

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The ROAM Research Study Therapy (LTOT) Version

for Pulmonary Disease, Chronic Obstructive

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: All ages

Code: NCT06810323·Recruiting·Listed Feb 2025

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Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT06853145·EARLY_Phase 1·Recruiting·Listed Feb 2025

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The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 40 - 101

Code: NCT06323876·Recruiting·Listed Mar 2024

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Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

for Insomnia

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 65+

Code: NCT05565833·Phase 2·Recruiting·Listed Oct 2022

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Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke

for Ischemic Stroke

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT06292117·Recruiting·Listed Mar 2024

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Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)

for Clostridioides Difficile Infection

Sites in Charlottesville & Roanoke

Sponsor: University of Virginia

Sex: All·Age: 18 - 105

Code: NCT04305769·Phase 2·Recruiting·Listed Mar 2020

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Charlottesville, Richmond +50 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

Apply to this trial

Meaning in Music-Based Pain Modulation

for The Focus of the Study is Healthy Volunteers

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 65

Code: NCT07036315·Recruiting·Listed Jun 2025

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Randomized Controlled Study Evaluating Genicular Artery Embolization Against Intra-Articular Corticosteroid Knee Injection for Osteoarthritic Knee Pain

for Knee Osteoarthritis (Knee OA)

1 location in Charlottesville

Sponsor: North American Science Associates Ltd.

Sex: All·Age: 40+

Code: NCT06872567·Recruiting·Listed Mar 2025

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FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma

for Advanced Melanoma

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT06472661·EARLY_Phase 1·Recruiting·Listed Jun 2024

Apply to this trial

Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)

for MINOCA

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 85

Code: NCT07182955·Recruiting·Listed Sep 2025

Apply to this trial