Paid Clinical Trials in Charlottesville, VA

As of September 2026, 525 paid clinical trials are recruiting in Charlottesville, Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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469 clinical trials

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Charlottesville +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

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Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Drug: Polatuzumab Vedotin

Sites in Charlottesville +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06015880·Phase 1·Recruiting·Listed Aug 2023

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Pre-Operative Window of ET to Inform RT Decisions (POWER II)

for Breast Cancer Female

Sites in Charlottesville, Culpeper +4 more locations

Sponsor: University of Virginia

Sex: Female·Age: 65+

Code: NCT06507618·Phase 3·Recruiting·Listed Jul 2024

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The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

Sites in Charlottesville +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting·Listed Jan 2025

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Charlottesville, Richmond +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Resilience Enhancement Following Sleep Treatment

for Chronic Low Back Pain (CLBP)

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT07298941·Phase 2·Recruiting·Listed Dec 2025

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Charlottesville, Midlothian +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture

for Orthopedic Disorder

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 50 - 85

Code: NCT06869343·Recruiting·Listed Mar 2025

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Simplified Post Op Rehabilitation for Ankle and Pilon Fractures

for Ankle Fractures

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 65

Code: NCT05280639·Recruiting·Listed Mar 2022

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Safety, Immunogenicity, and Efficacy of Therapeutic Mycobacterium Bovis BCG (BOOST)

for Mycobacterium Avium-intracellulare Infection

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT07094711·Phase 2·Recruiting·Listed Jul 2025

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Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder

for Premenstrual Dysphoric Disorder (PMDD)

Sites in Charlottesville +1 more location

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06704594·Phase 4·Recruiting·Listed Nov 2024

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Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome

for Metabolic Syndrome

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 21 - 60·Accepts healthy volunteers

Code: NCT04575844·Phase 4·Recruiting·Listed Oct 2020

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4D-MRI for Precision Medicine

for Healthy Volunteers

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 82·Accepts healthy volunteers

Code: NCT04657042·Recruiting·Listed Dec 2020

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Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

Sites in Charlottesville, Richmond +11 more locations

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting·Listed Mar 2020

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Cardioprotection in AML

for AML

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT04977180·Phase 2·Recruiting·Listed Jul 2021

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Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery

for Brain Injury

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 65

Code: NCT06810336·EARLY_Phase 1·Recruiting·Listed Feb 2025

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Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)

for Castrate Sensitive Prostate Cancer

1 location in Charlottesville

Sponsor: Paul Viscuse

Sex: Male·Age: 18+

Code: NCT06429813·Recruiting·Listed May 2024

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Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

for Sleep Disorders, Circadian Rhythm

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05701969·EARLY_Phase 1·Recruiting·Listed Jan 2023

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Sonodynamic Therapy in Patients With Recurrent GBM

for Recurrent Glioblastoma

1 location in Charlottesville

Sponsor: Shayan Moosa, MD

Sex: All·Age: 18 - 80

Code: NCT06039709·Phase 1·Recruiting·Listed Sep 2023

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A Global Study of the PETAL Consortium

for T-Cell and NK-Cell Neoplasm

Sites in Charlottesville +9 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06067347·Recruiting·Listed Oct 2023

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Vaginal Cuff Brachytherapy Fractionation Study

for Endometrial Cancer

Sites in Charlottesville +2 more locations

Sponsor: Kara Romano, MD

Sex: Female·Age: 18+

Code: NCT03785288·Phase 3·Recruiting·Listed Dec 2018

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Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

for Smoking Cessation

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05660525·Recruiting·Listed Dec 2022

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Kidney Function in People With Cystic Fibrosis in the Era of HEMT

for Cystic Fibrosis (CF)

Sites in Charlottesville +2 more locations

Sponsor: University of Virginia

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT06595420·Recruiting·Listed Sep 2024

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Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes

for Type 1 Diabetes (T1D)

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 45

Code: NCT07186660·Phase 2·Recruiting·Listed Sep 2025

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The Oxford Risk Factors And Non-Invasive Imaging Study

for Cardiovascular Diseases

Sites in Charlottesville +11 more locations

Sponsor: University of Oxford

Sex: All·Age: 18 - 99

Code: NCT05169333·Recruiting·Listed Dec 2021

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MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Monalizumab

Sites in Charlottesville +3 more locations

Sponsor: Hirva Mamdani

Sex: All·Age: 18+

Code: NCT05903092·Phase 2·Recruiting·Listed Jun 2023

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Charlottesville +53 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea

for FHA (Functional Hypothalamic Amenorrhea)

Sites in Charlottesville +1 more location

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 14 - 30

Code: NCT06533865·Phase 3·Recruiting·Listed Aug 2024

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Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Venetoclax

Sites in Charlottesville +3 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03523975·Phase 1, Phase 2·Recruiting·Listed May 2018

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HCMR Re-Imaging Study

for Hypertrophic Cardiomyopathy (HCM)

Sites in Charlottesville +5 more locations

Sponsor: Christopher Kramer

Sex: All·Age: 18 - 65

Code: NCT07054073·Recruiting·Listed Jul 2025

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Complex Adult Deformity Surgery (CADS)

for Adult Spinal Deformity

Sites in Charlottesville +15 more locations

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04194138·Recruiting·Listed Dec 2019

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Developing Hyperpolarized Gas MRI Signatures to Detect and Manage Acute Cellular Rejection

for Lung Transplant Rejection

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 80

Code: NCT07046910·Phase 2·Recruiting·Listed Jul 2025

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Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy

for Obesity in Children

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 12 - 21

Code: NCT06903923·Phase 2·Recruiting·Listed Apr 2025

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Transformative Research in Diabetic Nephropathy

for Diabetic Nephropathies

Sites in Charlottesville +12 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100

Code: NCT02986984·Recruiting·Listed Dec 2016

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BXCL501 After Stress to Increase Recovery Success

for Acute Stress Reaction

Sites in Charlottesville +2 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 65

Code: NCT06943404·Phase 2·Recruiting·Listed Apr 2025

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Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

for Type 2 Diabetes

Sites in Charlottesville +1 more location

Sponsor: University of Colorado, Denver

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT04791371·Recruiting·Listed Mar 2021

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A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for AML (Acute Myelogenous Leukemia)

Sites in Charlottesville +12 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 18 - 66

Code: NCT06859424·Phase 2·Recruiting·Listed Mar 2025

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Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology

for Electronic Cigarette Related Lung Damage

Sites in Charlottesville +1 more location

Sponsor: Y. Michael Shim, MD

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT06856525·Phase 2, Phase 3·Recruiting·Listed Mar 2025

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Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

for Non Small Cell Lung Cancer

Drug: Adagrasib

Sites in Charlottesville, Richmond +1 more location

Sponsor: Ryan Gentzler, MD

Sex: All·Age: 18+

Code: NCT06248606·Phase 2·Recruiting·Listed Feb 2024

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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

Sites in Charlottesville +50 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting·Listed Jul 2015

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