Paid Clinical Trials in Chattanooga, TN

As of September 2026, 126 paid clinical trials are recruiting in Chattanooga, Tennessee. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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118 clinical trials

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

Sites in Chattanooga, Knoxville +381 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in Chattanooga, Knoxville +170 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 Months - 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Chattanooga, Germantown +115 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

Sites in Chattanooga, Knoxville +185 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting·Listed May 2019

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

Sites in Chattanooga, Knoxville +151 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting·Listed May 2024

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Chattanooga, Knoxville +225 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

for Breast Cancer

Sites in Chattanooga +14 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04468061·Phase 2·Recruiting·Listed Jul 2020

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Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

for Down Syndrome (DS)

Sites in Chattanooga, Knoxville +10 more locations

Sponsor: Woolfson Eye Institute

Sex: All·Age: 8+

Code: NCT07135167·Phase 3·Recruiting·Listed Aug 2025

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Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases

for Keratoconus

Sites in Chattanooga, Knoxville +10 more locations

Sponsor: Woolfson Eye Institute

Sex: All·Age: 8+

Code: NCT07124910·Phase 3·Recruiting·Listed Aug 2025

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RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

for Neoplasms

Sites in Chattanooga +12 more locations

Sponsor: The Radiosurgery Society

Sex: All·Age: All ages

Code: NCT01885299·Recruiting·Listed Jun 2013

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ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis

for AChR-Ab Seropositive Generalized Myasthenia Gravis

Drug: Empasiprubart IV

Sites in Chattanooga +2 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07673627·Phase 2·Recruiting·Listed Jun 2026

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A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for Acute Migraine

Drug: Elismetrep

Sites in Chattanooga, Nashville +111 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18+

Code: NCT07674654·Phase 3·Recruiting·Listed Jun 2026

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Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease

for Graves Disease

Sites in Chattanooga, Memphis +47 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 70

Code: NCT07661056·Phase 3·Recruiting·Listed Jun 2026

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A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for Irritable Bowel Syndrome

Sites in Chattanooga, Knoxville +108 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 80

Code: NCT07519395·Phase 2·Recruiting·Listed Apr 2026

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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

for Eosinophilic Asthma

Sites in Chattanooga +33 more locations

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07323654·Phase 2·Recruiting·Listed Jan 2026

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Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

for Heart Failure

Sites in Chattanooga +10 more locations

Sponsor: CVRx, Inc.

Sex: All·Age: 18+

Code: NCT07232030·Recruiting·Listed Nov 2025

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A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

for Non-alcoholic Fatty Liver Disease

Sites in Chattanooga +57 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 75

Code: NCT07221188·Phase 3·Recruiting·Listed Oct 2025

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A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

for Non-alcoholic Fatty Liver Disease

Sites in Chattanooga +75 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 75

Code: NCT07221227·Phase 3·Recruiting·Listed Oct 2025

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Chattanooga, Franklin +70 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting·Listed Jul 2025

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Chattanooga, Nashville +63 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024

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A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

for Heart Failure

Drug: Finerenone

Sites in Chattanooga +45 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06024746·Phase 3·Recruiting·Listed Sep 2023

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

Sites in Chattanooga, Tullahoma +308 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025

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Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

Sites in Chattanooga, Nashville +38 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06380751·Phase 3·Recruiting·Listed Apr 2024

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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for Chronic Kidney Disease and Hypertension

Drug: Dapagliflozin

Sites in Chattanooga, Knoxville +115 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06742723·Phase 3·Recruiting·Listed Dec 2024

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Chattanooga, Tullahoma +132 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting·Listed Feb 2024

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

Sites in Chattanooga, Nashville +53 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting·Listed Dec 2024

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Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Chattanooga, Nashville +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 95

Code: NCT05061550·Phase 2·Recruiting·Listed Sep 2021

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

for Breast Cancer

Drug: Durvalumab

Sites in Chattanooga, Nashville +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06103864·Phase 3·Recruiting·Listed Oct 2023

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A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments

for Multiple Myeloma

Sites in Chattanooga, Nashville +9 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT05714839·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Chattanooga, Nashville +59 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting·Listed Oct 2024

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

Sites in Chattanooga +67 more locations

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting·Listed Feb 2025

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Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

for APOL1-Mediated Kidney Disease

Sites in Chattanooga, Nashville +76 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT06824987·Phase 2·Recruiting·Listed Feb 2025

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

Sites in Chattanooga, Oak Ridge +146 more locations

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting·Listed Jun 2023

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A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Chattanooga, Nashville +34 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for Neoplasms, Head and Neck

Drug: Dostarlimab

Sites in Chattanooga, Nashville +29 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06256588·Phase 3·Recruiting·Listed Feb 2024

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A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in Chattanooga, Nashville +25 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06417814·Phase 3·Recruiting·Listed May 2024

Apply to this trial