Paid Clinical Trials in Clearwater, FL

As of September 2026, 114 paid clinical trials are recruiting in Clearwater, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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107 clinical trials

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Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a)

for Lipoprotein Disorder

Sites in Clearwater, Tampa +14 more locations

Sponsor: Kylonova (Xiamen) Biopharma co., LTD.

Sex: All·Age: 18 - 80

Code: NCT07327840·Phase 2·Recruiting·Listed Jan 2026

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A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

Sites in Clearwater, Tampa +20 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting·Listed Dec 2025

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Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica

for Polymyalgia Rheumatica

Sites in Clearwater, Tampa +41 more locations

Sponsor: Sanofi

Sex: All·Age: 50+

Code: NCT07286214·Phase 4·Recruiting·Listed Dec 2025

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A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

for Gout

Sites in Clearwater, Tampa +16 more locations

Sponsor: Protalix

Sex: All·Age: 18+

Code: NCT07280156·Phase 2·Recruiting·Listed Dec 2025

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A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

Sites in Clearwater, Tampa +19 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06807424·Phase 3·Recruiting·Listed Feb 2025

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FebriDx® Pediatric Validation Study

for Acute Respiratory Infections (ARIs)

Sites in Clearwater, Tampa +8 more locations

Sponsor: Lumos Diagnostics

Sex: All·Age: 2 - 11

Code: NCT07211997·Recruiting·Listed Oct 2025

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Fertilo In Vitro Research Study and Trial

for In Vitro Maturation of Oocytes

Sites in Clearwater, Pembroke Pines +13 more locations

Sponsor: Gameto, Inc.

Sex: Female·Age: 18 - 35·Accepts healthy volunteers

Code: NCT06858111·Phase 3·Recruiting·Listed Mar 2025

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Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

for Systemic Lupus Erythematosus

Drug: Ianalumab

Sites in Clearwater, Tampa +17 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT06133972·Phase 3·Recruiting·Listed Nov 2023

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Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.

for Sciatica Acute

Sites in Clearwater, Oldsmar +6 more locations

Sponsor: Primus Pharmaceuticals

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06157177·Phase 4·Recruiting·Listed Dec 2023

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A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

for Diffuse Cutaneous Systemic Sclerosis

Drug: Ianalumab

Sites in Clearwater, Plantation +14 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06470048·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

BoxX-NoAF Clinical Trial

for Post Operative Atrial Fibrillation

Sites in Clearwater, Sarasota +22 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06989775·Recruiting·Listed May 2025

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Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

for Atrial Fibrillation (AF)

Sites in Clearwater, Tampa +10 more locations

Sponsor: Vektor Medical

Sex: All·Age: 22+

Code: NCT06935591·Recruiting·Listed Apr 2025

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Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

for Psoriatic Arthritis

Sites in Clearwater, Tampa +13 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06865105·Phase 2·Recruiting·Listed Mar 2025

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MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

for Coronary Artery Disease

Sites in Clearwater, Tampa +22 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 80

Code: NCT06271590·Recruiting·Listed Feb 2024

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A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)

for Myasthenia Gravis

Sites in Clearwater +5 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07673744·Phase 2·Recruiting·Listed Jun 2026

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Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden

for Sjögren´s Disease

Drug: Ianalumab

Sites in Clearwater, Tampa +14 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07621809·Phase 3·Recruiting·Listed Jun 2026

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EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

for Diffuse Cutaneous Systemic Sclerosis

Sites in Clearwater, Tampa +21 more locations

Sponsor: Mediar Therapeutics

Sex: All·Age: 18+

Code: NCT07287670·Phase 2·Recruiting·Listed Dec 2025

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CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

for Aortic Valve Stenosis

Sites in Clearwater +6 more locations

Sponsor: EmStop Inc

Sex: All·Age: 22+

Code: NCT07276711·Recruiting·Listed Dec 2025

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A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis (RA)

Drug: LY4213663

Sites in Clearwater, Daytona Beach +7 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07258849·Phase 1·Recruiting·Listed Dec 2025

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A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)

for Dry Eye Syndrome

Sites in Clearwater, Tampa +5 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06977724·Phase 1·Recruiting·Listed May 2025

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A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

for Systemic Lupus Erythematosus (SLE) or Cutaneous Lupus Erythematosus

Sites in Clearwater, Orlando +4 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06625671·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction

for Ischemic Heart Failure

Sites in Clearwater +3 more locations

Sponsor: BioCardia, Inc.

Sex: All·Age: 21 - 90

Code: NCT06258447·Recruiting·Listed Feb 2024

Apply to this trial

REINItiation of Antiretroviral Therapy Using Oral bicTegravir, emtrIcitAbine and Tenofovir alafenamidE

for HIV -1 Infection

Sites in Clearwater, Tampa +8 more locations

Sponsor: CAN Community Health

Sex: All·Age: 18+

Code: NCT07476339·Phase 4·Recruiting·Listed Mar 2026

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Clearwater, Safety Harbor +1087 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Clearwater, St. Petersburg +923 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Clearwater, Safety Harbor +594 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

Sites in Clearwater, Safety Harbor +612 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting·Listed Apr 2022

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

Sites in Clearwater, Safety Harbor +535 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

Sites in Clearwater, Safety Harbor +777 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

Sites in Clearwater, Tampa +444 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022

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Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

Sites in Clearwater, Tampa +324 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06958328·Phase 3·Recruiting·Listed May 2025

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

Sites in Clearwater, St. Petersburg +270 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting·Listed Jul 2024

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Clearwater, St. Petersburg +479 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

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Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

for Percutaneous Coronary Intervention

Drug: Inclisiran

Sites in Clearwater, Largo +133 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06909565·Phase 4·Recruiting·Listed Apr 2025

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Clearwater, Sarasota +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

Apply to this trial

RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

Sites in Clearwater, Riverview +46 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting·Listed Dec 2020

Apply to this trial

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Clearwater, Tampa +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Clearwater, St. Petersburg +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Clearwater, Safety Harbor +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Study of Screening Brain MRIs in Stage IV Breast Cancer

for Triple Negative Breast Cancer

1 location in Clearwater

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT05115474·Phase 2·Recruiting·Listed Nov 2021

Apply to this trial