Paid Clinical Trials in Clearwater, FL
As of August 2026, 114 paid clinical trials are recruiting in Clearwater, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Clearwater offers studies at sites including Morton Plant Hospital for conditions such as Systemic Lupus Erythematosus, Coronary Artery Disease, Heart Failure, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Clearwater
Trials by drug in Clearwater
Filter results
Newly added in Clearwater
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
105 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
SELUTION 4 De Novo Small Vessel IDE Trial
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
Prevail Global Study
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Top Research Study Locations in Clearwater
Researchers run research studies in Clearwater, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Morton Plant Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 15 |
| Clearwater Cardiovascular Consultants | Acute Myocardial Infarction, Arterial Disease of Legs, Below-the-knee Obstruction | 6 |
| Clinical Research of West Florida, Inc. | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Gout | 5 |
| Clinical Research Of West Florida - Phase I Unit | Rheumatoid Arthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus | 4 |
| BayCare Health System | Atrial Fibrillation (AF), Coronary Artery Disease, Heart Failure | 3 |
| Clearwater Cardiovascular and Interventional Consultants | Cardiovascular Diseases, Coronary Artery Disease, Heart Failure | 3 |
| Gastro Florida | C. Diff Infection, C.Difficile Diarrhea, CDI | 3 |
| BayCare Health | Aortic Insufficiency, Aortic Regurgitation, Aortic Valve Insufficiency | 2 |
| Clinical Res Of W Florida | Diffuse Cutaneous Systemic Sclerosis, Systemic Lupus Erythematosus | 2 |
| Clinical Research of West Florida | Arthritis, Psoriatic, Diffuse Cutaneous Systemic Sclerosis | 2 |
| Clinical Research of West Florida - Clearwater | COPD, Osteoarthritis, Knee | 2 |
| Clinical Research of West Florida, Inc | Rheumatoid Arthritis, Systemic Lupus Erythematosus | 2 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Breast Cancer, Breast Neoplasms | 2 |
| GSK Investigational Site | Irritable Bowel Syndrome, Systemic Lupus Erythematosus | 2 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Myasthenia Gravis, Relapsing Multiple Sclerosis | 2 |
| Tampa Bay Medical Research | Hypercholesterolemia, Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| ACCOMPLISH-1 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| ACCOMPLISH-2 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| Advanced Surgical Care of Clearwater | Lumbar Spinal Stenosis | 1 |
| American Arthritis and Rheumatology Associates LLC | Rheumatoid Arthritis | 1 |
| Anthos Investigational | Atrial Fibrillation (AF) | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| BayCare Health Systems | Atrial Fibrillation | 1 |
| BayCare Medical Group | Percutaneous Coronary Intervention, Peripheral Endovascular Intervention | 1 |
Active & Upcoming Studies in Clearwater (2026)
Recruiting trials in Clearwater grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cardiovascular (21 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- BoxX-NoAF Clinical Trial · AtriCure, Inc.
Cancer & tumors (19 active studies)
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Phase 3 · Pfizer
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (6 active studies)
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Neurology & pain (2 active studies)
- A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis · Phase 3 · Zenas BioPharma (USA), LLC
- A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) · TG Therapeutics, Inc.
Vaccines (1 active study)
HIV / STI (1 active study)
- REINItiation of Antiretroviral Therapy Using Oral bicTegravir, emtrIcitAbine and Tenofovir alafenamidE · Phase 4 · CAN Community Health
Common conditions studied in Clearwater
- Systemic Lupus Erythematosus (7 active studies)
- Coronary Artery Disease (5 active studies)
- Heart Failure (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Obesity (4 active studies)
- Rheumatoid Arthritis (4 active studies)
Leading research sponsors in Clearwater
- AstraZeneca
- AbbVie
- Boehringer Ingelheim
- Alliance for Clinical Trials in Oncology
- Concept Medical Inc.
Frequently asked questions
How many paid clinical trials are currently recruiting in Clearwater?
There are approximately 114 recruiting clinical trials in Clearwater, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Clearwater pay participants?
Most recruiting trials in Clearwater compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Clearwater?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Clearwater?
The most common conditions under active study in Clearwater include Systemic Lupus Erythematosus (7), Coronary Artery Disease (5), Heart Failure (5), Anatomic Stage II Breast Cancer AJCC v8 (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Clearwater?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Clearwater on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Clearwater?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Clearwater?
Recruiting research sites in Clearwater include Morton Plant Hospital, Clearwater Cardiovascular Consultants, Clinical Research of West Florida, Inc., among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Clearwater right now?
The largest active categories in Clearwater are Cardiovascular (21), Cancer & tumors (19), Diabetes & metabolic (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.