Paid Clinical Trials in Cleveland, OH

As of June 2026, 1,351 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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1,352 clinical trials

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A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for Major Depressive Disorder

27 locations incl. Gilbert

Sponsor: Definium Therapeutics US, Inc.

Sex: All·Age: 18 - 74

Code: NCT07592689·Phase 3·Recruiting

Apply to this trial

Dasatinib for HIV-1 Reservoir Reduction

for HIV Infections

3 locations incl. Chicago

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT07342491·Phase 1·Recruiting

Apply to this trial

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

14 locations incl. Birmingham

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

10 locations incl. Birmingham

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

24 locations incl. Dothan

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting

Apply to this trial

Humidity Asthma Interventions for Low Socioeconomic Status Children

for Pediatric Asthma

2 locations incl. Cleveland

Sponsor: Case Western Reserve University

Sex: All·Age: Up to 18

Code: NCT07453667·Recruiting

Apply to this trial

Ovarian Tissue Allo-transplantation

for Ovarian Failure

1 location in Cleveland

Sponsor: Rebecca Flyckt

Sex: Female·Age: 21 - 40·Accepts healthy volunteers

Code: NCT06673004·Not Yet Recruiting

Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities

for Tardive Dyskinesia

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06997198·Phase 4·Not Yet Recruiting

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

for Nonmelanoma Skin Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07241585·Not Yet Recruiting

Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for Advanced Biliary Tract Cancer

23 locations incl. Duarte

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07265674·Phase 3·Recruiting

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A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.

for Exocrine Pancreatic Insufficiency (EPI)

9 locations incl. Scottsdale

Sponsor: Aimmune Nestlé Health Science US R&D, LLC

Sex: All·Age: 18 - 85

Code: NCT07559175·Phase 2·Not Yet Recruiting

Phase 2 Study to Assess the Safety and Efficacy of ANG003

for Exocrine Pancreatic Insufficiency (EPI)

26 locations incl. Long Beach

Sponsor: Anagram Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07450547·Phase 2·Recruiting

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PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

13 locations incl. Scottsdale

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting

Apply to this trial

Baby Steps to Care

for Prenatal Follow Up Care

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07499648·Recruiting

Apply to this trial

Visugromab in Cachexia International Trial

for Cancer-associated Cachexia

6 locations incl. Clermont

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07112196·Phase 2, Phase 3·Recruiting

Apply to this trial

Neural Correlates of Suicidal Behavior in Youth

for Suicidal Ideation

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 14 - 24·Accepts healthy volunteers

Code: NCT07568054·Not Yet Recruiting

Menopausal HT for Women Living With HIV (HoT)

for HIV Infection

23 locations incl. Birmingham

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: Female·Age: 40 - 60

Code: NCT06856174·Phase 4·Recruiting

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

68 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting

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Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

for Atrial Fibrillation (AF)

22 locations incl. Birmingham

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT07298473·Recruiting

Apply to this trial

Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

24 locations incl. Birmingham

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting

Apply to this trial

PEP Buddy in Pulmonary Rehabilitation

for COPD

2 locations incl. Cincinnati

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 89

Code: NCT07404826·Not Yet Recruiting

HCMR Re-Imaging Study

for Hypertrophic Cardiomyopathy (HCM)

6 locations incl. Evanston

Sponsor: Christopher Kramer

Sex: All·Age: 18 - 65

Code: NCT07054073·Recruiting

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Direct Comparison of Cardiac CT With TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics

for Device Related Thrombosis

5 locations incl. Los Angeles

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT06523166·Recruiting

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Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy

for Chemotherapy-induced Peripheral Neuropathy

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07219472·Recruiting

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A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

for Advanced Renal Cell Carcinoma (RCC)

Drug: Cabozantinib

13 locations incl. New Haven

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07293351·Phase 1, Phase 2·Recruiting

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Healthy Aging in People With Epilepsy Program

for Epilepsy

1 location in Cleveland

Sponsor: Anny Reyes

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT06052605·Recruiting

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A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

for Alzheimer Disease

Drug: KarXT

6 locations incl. Gilbert

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 55 - 90

Code: NCT06947941·Phase 3·Recruiting

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A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

9 locations incl. Englewood

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting

Apply to this trial

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for Proteinuric Kidney Diseases

25 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07355296·Phase 2·Recruiting

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Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

for Breast Cancer

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: Female·Age: 18 - 65

Code: NCT04362826·Recruiting

Apply to this trial

Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes

for Epilepsy

1 location in Cleveland

Sponsor: Anny Reyes

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07509190·Recruiting

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A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas

for Glioblastoma

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07003542·Phase 2·Recruiting

Apply to this trial

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors

for Non-small Cell Lung Cancer Stage III

1 location in Cleveland

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07104630·Phase 2·Recruiting

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A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion

for Liver Transplant Disorder

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+

Code: NCT07315204·Recruiting

Apply to this trial

POP SINGER Pilot Study

for Chronic Pain

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT07450131·Recruiting

Apply to this trial

Sternal Plating High Risk

for Heart Diseases

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06660186·Recruiting

Apply to this trial

Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

for Hypertension

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: Female·Age: 18+

Code: NCT07363343·Recruiting

Apply to this trial