Paid Clinical Trials in Columbia, MO

As of August 2026, 228 paid clinical trials are recruiting in Columbia, Missouri. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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199 clinical trials

Early Neurovascular Adaptations in Aging Women

for Women

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06520982·EARLY_Phase 1·Recruiting·Listed Jul 2024

Apply to this trial

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

for Obesity

1 location in Columbia

Sponsor: VA Office of Research and Development

Sex: All·Age: 30 - 60·Accepts healthy volunteers

Code: NCT06745063·Phase 2·Recruiting·Listed Dec 2024

Apply to this trial

An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction

for Tobacco Use Disorder

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT03713424·Phase 2·Recruiting·Listed Oct 2018

Apply to this trial

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

for Cat Bite

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05846399·Phase 4·Recruiting·Listed May 2023

Apply to this trial

Impact GLP-1 Agonists Following Bariatric

for Morbid Obesity

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT06132477·Phase 4·Recruiting·Listed Nov 2023

Apply to this trial

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

for Non Small Cell Lung Cancer

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03551951·Recruiting·Listed Jun 2018

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Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

for Heart Failure With Reduced Ejection Fraction (HFrEF)

Sites in Columbia +12 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06964464·Phase 4·Recruiting·Listed May 2025

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Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

for Menopause

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06787066·EARLY_Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

Periprosthetic Fracture Registry (PPFx)

for Periprosthetic Fractures

Sites in Columbia +3 more locations

Sponsor: AO Innovation Translation Center

Sex: All·Age: 18+

Code: NCT03378557·Recruiting·Listed Dec 2017

Apply to this trial

Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome

for Diet Intervention

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06433115·Recruiting·Listed May 2024

Apply to this trial

Sleep as a Mechanism of Change in Alcohol Use

for Insomnia

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 49·Accepts healthy volunteers

Code: NCT06286774·Recruiting·Listed Feb 2024

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Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

for Pregnancy

Sites in Columbia, St Louis & Kansas City

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 18+

Code: NCT06741735·Recruiting·Listed Dec 2024

Apply to this trial

Laser In Situ Fenestration Study

for Aortic Aneurysm

1 location in Columbia

Sponsor: Jonathan Bath

Sex: All·Age: 18+

Code: NCT06411990·Recruiting·Listed May 2024

Apply to this trial

NeuroControl of Nicotine Dependence

for Nicotine Dependence

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06347055·Recruiting·Listed Apr 2024

Apply to this trial

Cognitive Rehabilitation Following Breast Cancer Treatment

for Breast Cancer Female

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 20 - 75

Code: NCT06545045·Recruiting·Listed Aug 2024

Apply to this trial

Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults

for Aging

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06689618·Recruiting·Listed Nov 2024

Apply to this trial

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

Sites in Columbia, St Louis +53 more locations

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting·Listed Nov 2020

Apply to this trial

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

for Alzheimer Disease and Related Dementias (ADRD)

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07120347·Recruiting·Listed Aug 2025

Apply to this trial

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

for Aging

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: Female·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06417177·EARLY_Phase 1·Recruiting·Listed May 2024

Apply to this trial

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

for Mental Health Issue

Sites in Columbia +2 more locations

Sponsor: University of Virginia

Sex: All·Age: 10 - 99·Accepts healthy volunteers

Code: NCT06047041·Recruiting·Listed Sep 2023

Apply to this trial

Dietary Fiber Effects on the Microbiome and Satiety

for Dietary Fiber

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 20 - 55·Accepts healthy volunteers

Code: NCT04611217·Recruiting·Listed Nov 2020

Apply to this trial

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Myasthenia Gravis

for Generalized Myasthenia Gravis

Sites in Columbia +1 more location

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06064695·Recruiting·Listed Oct 2023

Apply to this trial

Smoking Cessation Behavioral Treatment Study

for Tobacco Use Disorder

Sites in Columbia +1 more location

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03948893·Recruiting·Listed May 2019

Apply to this trial

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

for Hand Transplantation

Sites in Columbia, St Louis +1 more location

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT03610763·Recruiting·Listed Aug 2018

Apply to this trial

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

for Insomnia Chronic

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 6 - 12

Code: NCT04545606·Recruiting·Listed Sep 2020

Apply to this trial

A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

for Essential Thrombocythemia

Sites in Columbia, St Louis +39 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07623200·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Talar Osteochondral Lesions With Pilon Fractures

for Pilon Fractures

1 location in Columbia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18+

Code: NCT07553221·Recruiting·Listed Apr 2026

Apply to this trial

A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma

for Asthma

Sites in Columbia +10 more locations

Sponsor: AstraZeneca

Sex: All·Age: 4 - 11

Code: NCT07525375·Phase 2·Recruiting·Listed Apr 2026

Apply to this trial

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

for Clostridioides Difficile Infection

Sites in Columbia, St Louis +32 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07285213·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

for Amyotrophic Lateral Sclerosis

Sites in Columbia +4 more locations

Sponsor: Insmed Gene Therapy LLC

Sex: All·Age: 18 - 79

Code: NCT07290062·Phase 1·Recruiting·Listed Dec 2025

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A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

for HIV Infections

Sites in Columbia, Kansas City +33 more locations

Sponsor: ViiV Healthcare

Sex: All·Age: 18+

Code: NCT07202546·Phase 2·Recruiting·Listed Oct 2025

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

Sites in Columbia, St Louis +175 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

Sites in Columbia, Kansas City +111 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting·Listed Mar 2024

Apply to this trial

Product Surveillance Registry

for Cardiac Rhythm Disorders

Sites in Columbia, St Louis +127 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting·Listed Feb 2012

Apply to this trial

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

Sites in Columbia, St Louis +83 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting·Listed Dec 2005

Apply to this trial