Clinical Trials at UT Southwestern Medical Center

As of September 2026, 167 paid clinical trials are recruiting at UT Southwestern Medical Center, located at UT Southwestern Medical Center: Research Department, 6000 Harry Hines Blvd, Dallas, TX 75235, phone (214) 633-0022 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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169 clinical trials at UT Southwestern Medical Center

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

Sites in Dallas +18 more locations

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting·Listed Jul 2023

Apply to this trial

Multiple System Atrophy Multidisciplinary Clinic

for Multiple System Atrophy (MSA)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT03811808·Recruiting·Listed Jan 2019

Apply to this trial

The Role of Sirolimus in Preventing Functional Decline in Older Adults

for Aging

1 location in Dallas

Sponsor: Irina Timofte

Sex: All·Age: 65 - 80·Accepts healthy volunteers

Code: NCT05237687·Phase 2·Recruiting·Listed Feb 2022

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Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

for Heart Failure With Preserved Ejection Fraction

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05723679·Recruiting·Listed Feb 2023

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Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)

for Cervix Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Female·Age: 18+

Code: NCT06266338·Phase 2·Recruiting·Listed Feb 2024

Apply to this trial

Markers of Osteoporosis in Cystic Fibrosis

for Cystic Fibrosis

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT03921060·Phase 4·Recruiting·Listed Apr 2019

Apply to this trial

The Oxford Risk Factors And Non-Invasive Imaging Study

for Cardiovascular Diseases

Sites in Dallas, San Antonio +10 more locations

Sponsor: University of Oxford

Sex: All·Age: 18 - 99

Code: NCT05169333·Recruiting·Listed Dec 2021

Apply to this trial

Multiparametric Image Analysis and Correlation With Outcomes in Lung Cancer Screening and Early Stage Lung Cancer

for Lung Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT03563976·Recruiting·Listed Jun 2018

Apply to this trial

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

for Head and Neck Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT06477692·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

PSMA PET Response Guided SabR in High Risk Pca

for Prostate Adenocarcinoma

2 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 18 - 99

Code: NCT06044857·Phase 1·Recruiting·Listed Sep 2023

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Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy

for Prostate Cancer

1 location in Dallas

Sponsor: yair lotan

Sex: Male·Age: 30 - 80

Code: NCT02064673·Phase 3·Recruiting·Listed Feb 2014

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Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

for Transthyretin (TTR) Amyloid Cardiomyopathy

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 30 - 80

Code: NCT07196839·Recruiting·Listed Sep 2025

Apply to this trial

Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

Sites in Dallas, Austin +18 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting·Listed Aug 2025

Apply to this trial

Multicomponent Intervention Study- Blood Donors With High Cholesterol

for Lipid Metabolism Disorder

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 75

Code: NCT05693701·Recruiting·Listed Jan 2023

Apply to this trial

MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System

for Paralysis

1 location in Dallas

Sponsor: Nader Pouratian

Sex: All·Age: 18 - 65

Code: NCT05936619·Recruiting·Listed Jul 2023

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Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI)

for Brain Tumor Adult

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 70

Code: NCT03067467·Recruiting·Listed Mar 2017

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Converting HR+ Breast Cancer Into an Individualized Vaccine

for Breast Cancer

Sites in Dallas, Houston +3 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18 - 90

Code: NCT03804944·Phase 2·Recruiting·Listed Jan 2019

Apply to this trial

DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)

for Amputation

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 95

Code: NCT02994160·Recruiting·Listed Dec 2016

Apply to this trial

Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury

for TBI (Traumatic Brain Injury)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06467708·Recruiting·Listed Jun 2024

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Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions

for Hypertension

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT05168605·Recruiting·Listed Dec 2021

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Laryngeal Cryotherapy for Refractory Neurogenic Cough

for Upper-Airway Cough Syndrome

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT05665244·Recruiting·Listed Dec 2022

Apply to this trial

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

for Parkinson Disease

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03872102·Recruiting·Listed Mar 2019

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HIV+ Deceased Donor Heart Transplant Study for HIV+ Recipients

for HIV Infection

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06659952·Recruiting·Listed Oct 2024

Apply to this trial

Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort

for Invasive Mammary Carcinoma

Sites in Dallas +2 more locations

Sponsor: Sonya Reid

Sex: All·Age: 18+

Code: NCT05693766·Phase 2·Recruiting·Listed Jan 2023

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Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1

for Prostate Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: All ages

Code: NCT06353321·Recruiting·Listed Apr 2024

Apply to this trial

Transcutaneous Auricular Neurostimulation After Lumbar Surgery

for Pain, Postoperative

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06100172·Recruiting·Listed Oct 2023

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Effect of the Stellate Ganglion Block on the Retinal Microcirculation

for OCTA

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06797752·Recruiting·Listed Jan 2025

Apply to this trial

NARCOMS Registry: A Multiple Sclerosis Registry

for Multiple Sclerosis

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT01018537·Recruiting·Listed Nov 2009

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Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder

for Neuromyelitis Optica

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06398158·Recruiting·Listed May 2024

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Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

for Heart

1 location in Dallas

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 20 - 90

Code: NCT01258231·Recruiting·Listed Dec 2010

Apply to this trial

Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes

for Heart Failure

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: All ages

Code: NCT06593314·Recruiting·Listed Sep 2024

Apply to this trial

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Dallas, Plano +50 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

Apply to this trial

Brain Injury Education and Outpatient Navigation-1stBIEN

for Brain Injuries, Traumatic

Sites in Dallas +3 more locations

Sponsor: Seattle Children's Hospital

Sex: All·Age: 3+

Code: NCT05261477·Recruiting·Listed Mar 2022

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Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation

for Heart Failure

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 50+

Code: NCT06130059·Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

[18F]PT2385 PET/CT in Patients With Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in Dallas

Sponsor: Orhan Kemal Oz

Sex: All·Age: 18+

Code: NCT04989959·Phase 1·Recruiting·Listed Aug 2021

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Preventing Cognitive Decline by Reducing BP Target Trial

for Cognitive Decline

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 70+

Code: NCT05106036·Recruiting·Listed Nov 2021

Apply to this trial

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

for Overactive Bladder (OAB)

Sites in Dallas +8 more locations

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 22+

Code: NCT06797245·Recruiting·Listed Jan 2025

Apply to this trial

Sequential Treatment of Cabozantinib for Advanced Renal Cell Carcinoma (RCC)

for RCC

Drug: Cabozantinib

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT05931393·Phase 2·Recruiting·Listed Jul 2023

Apply to this trial

Impact of Foot Orthoses on Gait in Individuals With Ataxia

for Ataxia

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07720700·Recruiting·Listed Jul 2026

Apply to this trial

Periprosthetic Joint Infection Bubble Study

for Periprosthetic Joint Infection (PJI)

Sites in Dallas +2 more locations

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07599865·Phase 2·Recruiting·Listed May 2026

Apply to this trial