Paid Clinical Trials in Detroit, MI

As of September 2026, 708 paid clinical trials are recruiting in Detroit, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

656 clinical trials

Get a weekly email when new trials open in Detroit, MI.

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

Sites in Detroit, Ann Arbor +69 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

Apply to this trial

The THOR IDE Study

for Peripheral Artery Disease

Sites in Detroit +28 more locations

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting·Listed Jun 2023

Apply to this trial

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

Sites in Detroit +34 more locations

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting·Listed Nov 2021

Apply to this trial

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for Aortic Stenosis

Drug: Pelacarsen

Sites in Detroit, Royal Oak +31 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 80

Code: NCT05646381·Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Sites in Detroit, Grand Rapids +32 more locations

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT05128825·Phase 2·Recruiting·Listed Nov 2021

Apply to this trial

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for Graft-versus-host Disease (GVHD)

Drug: Ruxolitinib

Sites in Detroit, Ann Arbor +28 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06615050·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

Sites in Detroit +42 more locations

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

Sites in Detroit, Ann Arbor +68 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

Apply to this trial

A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

Sites in Detroit +30 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06428019·Phase 3·Recruiting·Listed May 2024

Apply to this trial

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for Advanced Melanoma

Drug: Nivolumab

Sites in Detroit +32 more locations

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT06112314·Phase 3·Recruiting·Listed Nov 2023

Apply to this trial

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Detroit, Ann Arbor +42 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting·Listed Feb 2023

Apply to this trial

J-Valve Transfemoral Pivotal Study

for Aortic Valve Regurgitation

Sites in Detroit +33 more locations

Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC

Sex: All·Age: 18+

Code: NCT06455787·Recruiting·Listed Jun 2024

Apply to this trial

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for Atopic Dermatitis

Drug: Upadacitinib

Sites in Detroit +65 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 63

Code: NCT06389136·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

Sites in Detroit +30 more locations

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting·Listed Oct 2020

Apply to this trial

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

Sites in Detroit +25 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

Sites in Detroit, Ann Arbor +35 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting·Listed Jun 2023

Apply to this trial

A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

for Chronic Graft-versus-host-disease

Sites in Detroit +12 more locations

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 2+

Code: NCT04710576·Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

Sites in Detroit, Ann Arbor +39 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting·Listed May 2015

Apply to this trial

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Detroit, Ann Arbor +56 more locations

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06479135·Phase 3·Recruiting·Listed Jun 2024

Apply to this trial

PARTNER 3 Trial - Aortic Valve-in-Valve

for Aortic Stenosis

Sites in Detroit +28 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT03003299·Recruiting·Listed Dec 2016

Apply to this trial

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

Sites in Detroit, Dearborn Heights +118 more locations

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting·Listed May 2023

Apply to this trial

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumors

Sites in Detroit +27 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05914116·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

Impella RP Flex with Smart Assist

for Right Ventricular (RV) Dysfunction

Sites in Detroit +30 more locations

Sponsor: Abiomed Inc.

Sex: All·Age: All ages

Code: NCT06637644·Recruiting·Listed Oct 2024

Apply to this trial

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Detroit +25 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07702578·Phase 3·Recruiting·Listed Jul 2026

Apply to this trial

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

Sites in Detroit +10 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting·Listed May 2026

Apply to this trial

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Teclistamab

Sites in Detroit +34 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07518186·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

for Type 2 Diabetes Mellitus

Sites in Detroit +25 more locations

Sponsor: Insulet Corporation

Sex: All·Age: 18 - 75

Code: NCT07521475·Recruiting·Listed Apr 2026

Apply to this trial

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for PROC

Sites in Detroit +11 more locations

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07470853·Phase 1·Recruiting·Listed Mar 2026

Apply to this trial

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

for Esophageal Squamous Cell Carcinoma

Sites in Detroit +14 more locations

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07503808·Phase 1·Recruiting·Listed Mar 2026

Apply to this trial

Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

for Hereditary Angioedema (HAE)

Sites in Detroit +14 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07428499·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

Sites in Detroit +28 more locations

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting·Listed Jan 2026

Apply to this trial

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

for Melanoma (Skin Cancer)

Sites in Detroit +19 more locations

Sponsor: Aminex Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07287917·Phase 1, Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

Sites in Detroit, Grand Rapids +32 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

Sites in Detroit +18 more locations

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting·Listed Dec 2025

Apply to this trial

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

for Locally Advanced / Metastatic Solid Tumors

Sites in Detroit, Grand Rapids +13 more locations

Sponsor: Crescent Biopharma, Inc.

Sex: All·Age: 18+

Code: NCT07335497·Phase 1, Phase 2·Recruiting·Listed Jan 2026

Apply to this trial

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

for Myasthenia Gravis

Sites in Detroit +11 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07294170·Recruiting·Listed Dec 2025

Apply to this trial

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

for Hepatocellular Carcinoma (HCC)

Drug: Ipilimumab

Sites in Detroit +10 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07291076·Phase 1, Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

for AChR-Ab Seropositive Generalized Myasthenia Gravis

Drug: Empasiprubart IV

Sites in Detroit +10 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07284420·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

for Chronic Lymphocytic Leukemia (CLL)

Sites in Detroit +24 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07221500·Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Detroit, Grand Rapids +18 more locations

Sponsor: C4 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284758·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial