Oncology Clinical Trials in Duarte, CA

As of September 2026, 276 paid clinical trials are recruiting for Oncology in Duarte, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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280 clinical trials for Oncology

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A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for Lymphoma, Non-Hodgkin

Sites in Duarte +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07101328·Phase 1·Recruiting·Listed Aug 2025

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A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Osimertinib

Sites in Duarte, Irvine +13 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155187·Phase 2, Phase 3·Recruiting·Listed Sep 2025

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

Sites in Duarte, Los Angeles +19 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting·Listed Jun 2024

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A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

for Advanced/Metastatic Solid Tumors

Sites in Duarte, Los Angeles +19 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07090499·Phase 1·Recruiting·Listed Jul 2025

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A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for Lymphoma

Drug: Glofitamab

Sites in Duarte, Los Angeles +18 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06084936·Phase 3·Recruiting·Listed Oct 2023

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A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

for Solid Malignancies

Sites in Duarte, Los Angeles +17 more locations

Sponsor: Immunome, Inc.

Sex: All·Age: 18+

Code: NCT06823167·Phase 1·Recruiting·Listed Feb 2025

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

for Esophageal Cancer

Sites in Duarte, Cerritos +13 more locations

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217704·Phase 3·Recruiting·Listed Oct 2025

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A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer

Drug: Bevacizumab

Sites in Duarte, Santa Monica +15 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06820463·Phase 2·Recruiting·Listed Feb 2025

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Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

for Ovarian Cancer

Sites in Duarte, Palo Alto +15 more locations

Sponsor: Xencor, Inc.

Sex: All·Age: 15+

Code: NCT06276491·Phase 1·Recruiting·Listed Feb 2024

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndromes

Sites in Duarte, Glendale +20 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06499285·Phase 3·Recruiting·Listed Jul 2024

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A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for Colorectal Neoplasms

Sites in Duarte +20 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT06131840·Phase 1·Recruiting·Listed Nov 2023

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A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

for Metastatic Breast Cancer

Sites in Duarte, Burbank +14 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT05894239·Phase 3·Recruiting·Listed Jun 2023

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

Sites in Duarte +17 more locations

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024

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A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Duarte +11 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06172478·Phase 2·Recruiting·Listed Dec 2023

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Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

for Biliary Tract Cancer

Sites in Duarte +12 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06282575·Phase 3·Recruiting·Listed Feb 2024

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A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for Neoplasms

Sites in Duarte +12 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06150157·Phase 1·Recruiting·Listed Nov 2023

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Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

for Endometrial Cancer

Sites in Duarte, Los Angeles +15 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT06293898·Phase 1·Recruiting·Listed Mar 2024

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A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Duarte +14 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06121843·Phase 1·Recruiting·Listed Nov 2023

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

Sites in Duarte, Los Angeles +18 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting·Listed Jun 2021

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PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)

for Hematologic Malignancies

Sites in Duarte +10 more locations

Sponsor: Pulmotect, Inc.

Sex: All·Age: 18+

Code: NCT06665100·Phase 2·Recruiting·Listed Oct 2024

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Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

for Gastric or Gastroesophageal Junction Adenocarcinoma

Sites in Duarte, Los Angeles +8 more locations

Sponsor: Phanes Therapeutics

Sex: All·Age: 18+

Code: NCT05482893·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for Metastatic Melanoma

Drug: Lifileucel

Sites in Duarte, Los Angeles +16 more locations

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05727904·Phase 3·Recruiting·Listed Feb 2023

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Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

for Hematologic Malignancies

Sites in Duarte +9 more locations

Sponsor: Sellas Life Sciences Group

Sex: All·Age: 12+

Code: NCT04588922·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for Non-Small Cell Lung Cancer

Drug: Bevacizumab

Sites in Duarte, Los Angeles +18 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05005403·Phase 1·Recruiting·Listed Aug 2021

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A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

for Advanced Solid Tumors

Sites in Duarte +8 more locations

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06760819·Phase 2·Recruiting·Listed Jan 2025

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A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

for SST2-positive Neuroendocrine Neoplasms

Sites in Duarte, Orange +21 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07129252·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

for Acute Myeloid Leukemia

Sites in Duarte, Stanford +6 more locations

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 12 - 78

Code: NCT03802695·Phase 1·Recruiting·Listed Jan 2019

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A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

for Ovarian Cancer

Drug: Cemiplimab

Sites in Duarte, Orange +10 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT04590326·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

Sites in Duarte, Los Angeles +22 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

for Breast Cancer

Sites in Duarte, Fullerton +20 more locations

Sponsor: Celcuity Inc

Sex: All·Age: 18+

Code: NCT06757634·Phase 3·Recruiting·Listed Jan 2025

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Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

Sites in Duarte, Los Angeles +17 more locations

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting·Listed Oct 2024

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A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Duarte, Irvine +19 more locations

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06588478·Phase 2·Recruiting·Listed Sep 2024

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A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for Urothelial Carcinoma Bladder

Sites in Duarte, Irvine +10 more locations

Sponsor: Aktis Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07020117·Phase 1·Recruiting·Listed Jun 2025

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

Sites in Duarte, Beverly Hills +16 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting·Listed Oct 2018

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A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

for Solid Tumor, Adult

Sites in Duarte, San Diego +8 more locations

Sponsor: Corbus Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06265727·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

Sites in Duarte, Orange +22 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting·Listed Aug 2023

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A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Duarte +20 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05473910·Phase 1·Recruiting·Listed Jul 2022

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A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

for Hepatocellular Carcinoma

Drug: Livmoniplimab

Sites in Duarte, Orange +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06109272·Phase 2, Phase 3·Recruiting·Listed Oct 2023

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A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

for Gastric Adenocarcinoma

Sites in Duarte, Santa Monica +12 more locations

Sponsor: Toray Industries, Inc

Sex: All·Age: 18+

Code: NCT06038578·Phase 2·Recruiting·Listed Sep 2023

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

Sites in Duarte, Long Beach +15 more locations

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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Conditions in Oncology (Duarte, CA)

Solid tumor· 50 Acute myeloid leukemia (AML)· 30 Non-small cell lung cancer (NSCLC)· 29 Breast cancer· 26 Hematologic malignancy· 26 Myelodysplastic syndromes (MDS)· 25 Colorectal cancer· 19 Prostate cancer· 18 Ovarian cancer· 17 Pancreatic cancer· 15 Multiple myeloma· 14 Non-Hodgkin lymphoma· 14 Cancer (any)· 14 Metastatic breast cancer· 13 Gastric cancer· 13 Esophageal cancer· 13 Head and neck cancer· 13 Endometrial cancer· 11 Acute lymphoblastic leukemia· 11 Bladder cancer· 10 Diffuse large B-cell lymphoma (DLBCL)· 10 Chronic lymphocytic leukemia (CLL)· 9 Leukemia (other)· 9 Lung cancer· 8 Kidney cancer· 8 Myelofibrosis· 8 Mantle cell lymphoma· 8 Melanoma· 8 Cervical cancer· 7 Hodgkin lymphoma· 7 Gastroesophageal junction cancer· 6 Liver cancer· 6 Biliary tract cancer· 6 Triple-negative breast cancer· 5 Metastatic prostate cancer· 5 Glioblastoma· 5 Myeloproliferative neoplasm· 5 Marginal zone lymphoma· 5 Small lymphocytic lymphoma· 5 Follicular lymphoma· 4 Sarcoma· 4 Small cell lung cancer· 3 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Neuroendocrine tumors· 3 Chronic myelomonocytic leukemia· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Rhabdomyosarcoma· 1 Neuroblastoma· 1