Paid Clinical Trials in Duarte, CA

As of August 2026, 538 paid clinical trials are recruiting in Duarte, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 12, 2026.

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502 clinical trials

Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma

for Recurrent Plasma Cell Myeloma

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05363111·Phase 1·Recruiting·Listed May 2022

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Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma

for Folliculotropic Mycosis Fungoides

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT04930653·Phase 2·Recruiting·Listed Jun 2021

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Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer

for Lung Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05384769·Recruiting·Listed May 2022

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Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

for Cytomegaloviral Infection

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 1 - 21

Code: NCT03354728·Phase 1, Phase 2·Recruiting·Listed Nov 2017

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Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy

for Advanced Prostate Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 60+

Code: NCT05869682·Phase 2·Recruiting·Listed May 2023

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Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial

for Hematopoietic and Lymphoid System Neoplasm

Sites in Duarte, Upland & Lancaster

Sponsor: City of Hope Medical Center

Sex: All·Age: 65+

Code: NCT06022965·Recruiting·Listed Sep 2023

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Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study

for B-Cell Non-Hodgkin Lymphoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+

Code: NCT06052826·Phase 2·Recruiting·Listed Sep 2023

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Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06260033·Phase 2·Recruiting·Listed Feb 2024

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

Sites in Duarte, Palo Alto +8 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting·Listed Jun 2025

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Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma

for Marginal Zone Lymphoma

Sites in Duarte +3 more locations

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT05296070·Phase 2·Recruiting·Listed Mar 2022

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Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

for Recurrent Grade 1 Follicular Lymphoma

Drug: Polatuzumab Vedotin

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06453044·Phase 2·Recruiting·Listed Jun 2024

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Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

for Recurrent Transformed Chronic Lymphocytic Leukemia

Drug: Odronextamab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06735664·Phase 1·Recruiting·Listed Dec 2024

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External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease

for Extramedullary Disease in Multiple Myeloma

Drug: Talquetamab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06572605·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases

for Metastatic Malignant Neoplasm in the Bone

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06549478·Phase 1·Recruiting·Listed Aug 2024

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Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid Tumors

for Metastatic Malignant Solid Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05733949·Recruiting·Listed Feb 2023

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Prediction of Neoadjuvant Chemotherapy Response in Pancreatic Cancer

for Pancreatic Ductal Adenocarcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07226154·Recruiting·Listed Nov 2025

Apply to this trial

Iron Deficiency Anemia (IDA) and the Brain

for IDA - Iron Deficiency Anemia

Sites in Duarte & Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: Female·Age: 16 - 60·Accepts healthy volunteers

Code: NCT05929729·Phase 4·Recruiting·Listed Jul 2023

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

Sites in Duarte, Orange +112 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

Sites in Duarte +2 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting·Listed Jan 2022

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Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate Cancer

for Stage I Prostate Cancer AJCC v7

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 18+

Code: NCT04775355·Recruiting·Listed Mar 2021

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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

for B-cell Acute Lymphoblastic Leukemia

Sites in Duarte, Los Angeles +22 more locations

Sponsor: Pediatric Transplantation & Cellular Therapy Consortium

Sex: All·Age: 1 - 25

Code: NCT03509961·Phase 2·Recruiting·Listed Apr 2018

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Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models

for Gastrointestinal Neoplasm Malignant

1 location in Duarte

Sponsor: Chinese Academy of Sciences

Sex: All·Age: 18+

Code: NCT06002425·Recruiting·Listed Aug 2023

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A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Arcadia +9 more locations

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT07741968·Recruiting·Listed Aug 3, 2026

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A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

for Essential Thrombocythemia

Sites in Duarte, Los Angeles +39 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07623200·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

Sites in Duarte, Irvine +22 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting·Listed May 2026

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REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Drug: Cemiplimab

Sites in Duarte +3 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07594106·Phase 1, Phase 2·Recruiting·Listed May 2026

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A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Duarte +3 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07581002·Phase 2, Phase 3·Recruiting·Listed May 2026

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer (epNEC)

Drug: Obrixtamig

Sites in Duarte, Santa Monica +18 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Recruiting·Listed Apr 2026

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

Sites in Duarte, Fullerton +70 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026

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A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Duarte, Irvine +24 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07365241·Phase 3·Recruiting·Listed Jan 2026

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An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for Stomatitis

Sites in Duarte, Glendale +28 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07357597·Phase 4·Recruiting·Listed Jan 2026

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A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs

for Prostate Cancer

Sites in Duarte, San Francisco +6 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07336446·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Duarte, Los Angeles +46 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for Esophageal Squamous Cell Carcinoma

Sites in Duarte, Orange +8 more locations

Sponsor: Plexium, Inc.

Sex: All·Age: 18+

Code: NCT07284186·Phase 1·Recruiting·Listed Dec 2025

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Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation

for Graft Versus Host Disease

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 7+

Code: NCT07235501·Recruiting·Listed Nov 2025

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A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Duarte, Orange +33 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting·Listed Oct 2025

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Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

Sites in Duarte +4 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

Sites in Duarte +9 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting·Listed Jul 2025

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

Sites in Duarte, Irvine +46 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting·Listed May 2025

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

Sites in Duarte, Los Angeles +42 more locations

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial