Paid Clinical Trials in Duarte, CA

As of August 2026, 538 paid clinical trials are recruiting in Duarte, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 12, 2026.

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502 clinical trials

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for Metastatic Malignant Solid Neoplasm

Sites in Duarte, South Pasadena +16 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05372614·Phase 1·Recruiting·Listed May 2022

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A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

for Non-small Cell Lung Cancer

Sites in Duarte, Santa Monica +12 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05877599·Phase 1·Recruiting·Listed May 2023

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Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

for Distal Bile Duct Adenocarcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05285358·Phase 1·Recruiting·Listed Mar 2022

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Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for Solid Tumor

Drug: INBRX-106

Sites in Duarte, Glendale +11 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 18+

Code: NCT04198766·Phase 1, Phase 2·Recruiting·Listed Dec 2019

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Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

for Clear Cell Renal Cell Carcinoma

Sites in Duarte, Sacramento +18 more locations

Sponsor: Xencor, Inc.

Sex: All·Age: 18+

Code: NCT05433142·Phase 1·Recruiting·Listed Jun 2022

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A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for Recurrent Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06763341·Phase 1·Recruiting·Listed Jan 2025

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

Sites in Duarte, Los Angeles +16 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting·Listed Jan 2024

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Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for Ovarian Cancer

Sites in Duarte, Irvine +8 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05797168·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer

for Breast Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06130826·Phase 1·Recruiting·Listed Nov 2023

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AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

for Multiple Myeloma

Sites in Duarte, Irvine +6 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06106945·Phase 1, Phase 2·Recruiting·Listed Oct 2023

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A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Duarte, Orange +59 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06496178·Phase 3·Recruiting·Listed Jul 2024

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Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

for B-cell Non-Hodgkin Lymphoma

Sites in Duarte +16 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06526793·Phase 2·Recruiting·Listed Jul 2024

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AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

for Lymphoma

Sites in Duarte +6 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT06137144·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for HER2-positive Gastric Cancer

Drug: Rilvegostomig

Sites in Duarte, Upland +43 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06764875·Phase 3·Recruiting·Listed Jan 2025

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A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome

for Myelodysplastic Syndromes

Sites in Duarte, Irvine +4 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06847867·Phase 2·Recruiting·Listed Feb 2025

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AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

Sites in Duarte, Los Angeles +8 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT06137118·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for Solid Tumor

Sites in Duarte, La Jolla +15 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06384807·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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Study of AZD0754 in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Duarte +12 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT06267729·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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