Paid Clinical Trials in Evanston, IL

As of September 2026, 175 paid clinical trials are recruiting in Evanston, Illinois. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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162 clinical trials

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A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

for Head and Neck Squamous Cell Carcinoma (HNSCC)

Drug: Cemiplimab

Sites in Evanston +17 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06769698·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

for Schizophrenia

Drug: KarXT

Sites in Evanston +16 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07101094·Recruiting·Listed Aug 2025

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A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies

for NSCLC

Drug: EP0031

Sites in Evanston +14 more locations

Sponsor: Ellipses Pharma

Sex: All·Age: 18+

Code: NCT05443126·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Vivistim Registry for Paired VNS Therapy (GRASP)

for Upper Extremity Problem

Sites in Evanston, Elk Grove Village +13 more locations

Sponsor: MicroTransponder Inc.

Sex: All·Age: 22+

Code: NCT05301140·Recruiting·Listed Mar 2022

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Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

Sites in Evanston +15 more locations

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting·Listed Mar 2025

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Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

for Nausea

Sites in Evanston +11 more locations

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18+

Code: NCT06464926·Recruiting·Listed Jun 2024

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Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

Sites in Evanston, Chicago +19 more locations

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting·Listed Jan 2016

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Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

for Breast Reconstruction Surgery

Sites in Evanston +19 more locations

Sponsor: W.L.Gore & Associates

Sex: Female·Age: 22+

Code: NCT06556654·Recruiting·Listed Aug 2024

Apply to this trial

Pivotal Study for the Cardiac Performance System (CPS)

for Cardiovascular Diseases

Sites in Evanston +9 more locations

Sponsor: Sensydia Corporation

Sex: All·Age: 18+

Code: NCT06870591·Recruiting·Listed Mar 2025

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EFS of the CardioMech MVRS

for Mitral Regurgitation

Sites in Evanston +9 more locations

Sponsor: CardioMech AS

Sex: All·Age: 18+

Code: NCT04820764·Recruiting·Listed Mar 2021

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A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for Advanced Solid Tumor

Sites in Evanston +12 more locations

Sponsor: Volastra Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05902988·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for Lymphoma Diffuse Large B-cell

Sites in Evanston, Chicago +3 more locations

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284433·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

for Depressive Disorder, Major

Sites in Evanston +9 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 12 - 17

Code: NCT07227454·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Falcon Real World Evidence Registry

for Cancer

Sites in Evanston +1 more location

Sponsor: Exact Sciences Corporation

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06589310·Recruiting·Listed Sep 2024

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Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

for Low Back Pain

Sites in Evanston, Park Ridge +8 more locations

Sponsor: Aclarion

Sex: All·Age: 18 - 70

Code: NCT06661850·Recruiting·Listed Oct 2024

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Personal BP - CAI Study

for Blood Pressure

1 location in Evanston

Sponsor: Becton, Dickinson and Company

Sex: All·Age: 45+

Code: NCT06492746·Recruiting·Listed Jul 2024

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Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC)

for Necrotizing Enterocolitis

Sites in Evanston +7 more locations

Sponsor: Noveome Biotherapeutics, formerly Stemnion

Sex: All·Age: 2 Weeks - 8 Weeks

Code: NCT06315738·Phase 1, Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

for Breast Cancer

Sites in Evanston +3 more locations

Sponsor: Carevive Systems, Inc.

Sex: All·Age: 18+

Code: NCT05974150·Recruiting·Listed Aug 2023

Apply to this trial

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation

for Atrial Fibrillation

Sites in Evanston +3 more locations

Sponsor: Volta Medical

Sex: All·Age: 21+

Code: NCT06056271·Recruiting·Listed Sep 2023

Apply to this trial

GORE® ENFORM Biomaterial Product Study

for Hernia, Ventral

Sites in Evanston +6 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT04718168·Recruiting·Listed Jan 2021

Apply to this trial

Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease

for Alzheimer Disease

1 location in Evanston

Sponsor: CereMark Pharma, LLC

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT06254469·Phase 3·Recruiting·Listed Feb 2024

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Feasibility and Accuracy of a Novel Pleural Drain Gas Analyzer in Detecting Air Leaks

for Air Leak From Lung

1 location in Evanston

Sponsor: Lung Healing Technologies Inc

Sex: All·Age: 18+

Code: NCT06548386·Recruiting·Listed Aug 2024

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Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment

for Myasthenia Gravis

1 location in Evanston

Sponsor: ZS Associates

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06866483·Recruiting·Listed Mar 2025

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ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients.

for ICU Acquired Weakness

1 location in Evanston

Sponsor: Endeavor Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07699562·Recruiting·Listed Jul 2026

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Structured Opportunities for Connection to Improve Aging-related Loneliness

for Loneliness

1 location in Evanston

Sponsor: Endeavor Health

Sex: All·Age: 55+

Code: NCT07708844·Recruiting·Listed Jul 2026

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Implementation of Communication Disability Collection and Accommodations in Primary Care Settings

for Communication Disabilities

Sites in Evanston, Chicago +3 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07656584·Recruiting·Listed Jun 2026

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Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

for Psychopathology

1 location in Evanston

Sponsor: Northwestern University

Sex: All·Age: 10 - 18

Code: NCT07641244·Recruiting·Listed Jun 2026

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Evanston, Glenview +623 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Evanston, Skokie +1087 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Evanston, Glenview +923 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

Sites in Evanston, Glenview +266 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025

Apply to this trial

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

Sites in Evanston, Glenview +290 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in Evanston, Glenview +427 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Sleep, Dreaming, and Virtual Reality for Mental Health

for Anxiety

Sites in Evanston +1 more location

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07408206·EARLY_Phase 1·Recruiting·Listed Feb 2026

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Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia

Sites in Evanston, Glenview +156 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18 - 39

Code: NCT03150693·Phase 3·Recruiting·Listed May 2017

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Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for Smoldering Plasma Cell Myeloma

Drug: Daratumumab

Sites in Evanston, Glenview +482 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03937635·Phase 3·Recruiting·Listed May 2019

Apply to this trial

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

Sites in Evanston, Glenview +777 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for Astrocytoma, IDH-Mutant, Grade 3

Drug: Vorasidenib

Sites in Evanston, Glenview +115 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 12+

Code: NCT07215910·Phase 3·Recruiting·Listed Oct 2025

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in Evanston, Glenview +441 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023

Apply to this trial

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

Sites in Evanston, Glenview +328 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024

Apply to this trial