Paid Clinical Trials in Gainesville, FL

As of September 2026, 548 paid clinical trials are recruiting in Gainesville, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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485 clinical trials

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Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

for Polyarticular Course Juvenile Idiopathic Arthritis (JIA)

Sites in Gainesville +3 more locations

Sponsor: Duke University

Sex: All·Age: 2 - 17

Code: NCT06654882·Phase 3·Recruiting·Listed Oct 2024

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Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

for Advanced Malignant Solid Neoplasm

Sites in Gainesville +2 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05053971·Phase 1, Phase 2·Recruiting·Listed Sep 2021

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Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients

for Heart Transplant Rejection

Sites in Gainesville, Tallahassee +2 more locations

Sponsor: University of Florida

Sex: All·Age: 10 - 21

Code: NCT05732779·Recruiting·Listed Feb 2023

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A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients

for Cognitive Impairment

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 60 - 95·Accepts healthy volunteers

Code: NCT05998031·Recruiting·Listed Aug 2023

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The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients

for Lung Transplant

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT03886961·Recruiting·Listed Mar 2019

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Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction

for Breast Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 18 - 80

Code: NCT06461650·Recruiting·Listed Jun 2024

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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

Sites in Gainesville, Tampa +28 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting·Listed Jul 2020

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Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

for Sepsis, Trauma Injury

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT05357170·Recruiting·Listed May 2022

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Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis

for Sepsis

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05110937·Recruiting·Listed Nov 2021

Apply to this trial

Pervasive Sensing and AI in Intelligent ICU

for Critical Illness

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT05127265·Recruiting·Listed Nov 2021

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

Sites in Gainesville, St. Petersburg +20 more locations

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting·Listed May 2023

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Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome

for Healthy

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 45 - 65·Accepts healthy volunteers

Code: NCT06538415·Recruiting·Listed Aug 2024

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A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia

for Endometrioid Endometrial Adenocarcinoma

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 18+

Code: NCT07107334·Phase 2·Recruiting·Listed Aug 2025

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Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure

for Heart Failure

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT06979726·Phase 4·Recruiting·Listed May 2025

Apply to this trial

Improving Veteran Referral to Cardiac Rehabilitation

for Cardiovascular Disease

Sites in Gainesville +2 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07079358·Recruiting·Listed Jul 2025

Apply to this trial

High Intensity Focused Ultrasound in Prostate Cancer

for Prostate Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Male·Age: 18+

Code: NCT06402357·Phase 2·Recruiting·Listed May 2024

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Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

for Deep Venous Thrombosis

Sites in Gainesville, St. Petersburg +18 more locations

Sponsor: Yale University

Sex: All·Age: Up to 17

Code: NCT04924322·Phase 2, Phase 3·Recruiting·Listed Jun 2021

Apply to this trial

The PROACTIVE Study for Black Elders

for Musculoskeletal Pain

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 50 - 92

Code: NCT06512727·Recruiting·Listed Jul 2024

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Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

for Acute Lymphoblastic Leukemia

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 6 Months - 39

Code: NCT05800210·Phase 2·Recruiting·Listed Apr 2023

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Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults

for Cognitive Dysfunction

Sites in Gainesville & Jacksonville

Sponsor: University of Florida

Sex: All·Age: 65+

Code: NCT05830942·Recruiting·Listed Apr 2023

Apply to this trial

Clinical Orthopaedic Data Bank (Acute and Chronic)

for Osteoarthritis

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: All ages

Code: NCT00411060·Recruiting·Listed Dec 2006

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A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

for Adult Glioblastoma

Sites in Gainesville +1 more location

Sponsor: University of Florida

Sex: All·Age: 4+

Code: NCT04573140·Phase 1·Recruiting·Listed Oct 2020

Apply to this trial

ALS/MND Natural History Study Data Repository

for ALS

Sites in Gainesville +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Gainesville, Plant City +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

Apply to this trial

Trial of Precision Medicine in Emergency Departments

for Pharmacogenomic Drug Interaction

Sites in Gainesville & Jacksonville

Sponsor: University of Florida

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT06448091·Recruiting·Listed Jun 2024

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Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease

for Parkinson Disease

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT06911229·Recruiting·Listed Apr 2025

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Gainesville, Tampa +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

Apply to this trial

Spinal Networks of Balance Learning and Retention in Older Adults

for Aging

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 65 - 95·Accepts healthy volunteers

Code: NCT06517043·Recruiting·Listed Jul 2024

Apply to this trial

External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial

for Severe Traumatic Brain Injury

Sites in Gainesville +5 more locations

Sponsor: Brain Trauma Foundation

Sex: All·Age: 18 - 65

Code: NCT05889650·Recruiting·Listed Jun 2023

Apply to this trial

Developing a Scalable Tobacco Cessation Program for Cancer Survivors and Caregivers

for Nicotine Use

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06851936·Recruiting·Listed Feb 2025

Apply to this trial

Zinc as an Adjunctive Therapy for Cervical Dystonia

for Cervical Dystonia

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 89

Code: NCT07140874·Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC)

for Emergency Department Visit

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06330207·Recruiting·Listed Mar 2024

Apply to this trial

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

Sites in Gainesville +16 more locations

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

for Craniopharyngioma, Child

Sites in Gainesville +14 more locations

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 1 - 39

Code: NCT05465174·Phase 2·Recruiting·Listed Jul 2022

Apply to this trial

Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

Sites in Gainesville, Miami +11 more locations

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting·Listed Jan 2024

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Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care

for Tobacco Use Cessation

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05415761·Recruiting·Listed Jun 2022

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Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

for FSHD

Sites in Gainesville +15 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: All ages

Code: NCT04635891·Recruiting·Listed Nov 2020

Apply to this trial

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Gainesville +82 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

for Pain

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 45 - 85·Accepts healthy volunteers

Code: NCT05761860·EARLY_Phase 1·Recruiting·Listed Mar 2023

Apply to this trial

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

for Oropharyngeal Squamous Cell Carcinoma

Sites in Gainesville, Jacksonville +1 more location

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT05268614·Phase 2·Recruiting·Listed Mar 2022

Apply to this trial