Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Changefor Advanced Lung Non-Small Cell CarcinomaDrug: Osimertinib345 locations incl. AnchorageSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT03191149·Phase 2·RecruitingApply to this trial
Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphomafor Classic Follicular LymphomaDrug: Mosunetuzumab270 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT06337318·Phase 3·RecruitingApply to this trial
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Studyfor Clinical Stage III Cutaneous Melanoma AJCC v8Drug: Cabozantinib223 locations incl. PhoenixSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT05136196·Phase 2·RecruitingApply to this trial
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Programfor Cigarette Smoking-Related Carcinoma222 locations incl. KingmanSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT05008848·Phase 3·RecruitingApply to this trial
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancerfor Oropharyngeal p16INK4a-Negative Squamous Cell CarcinomaDrug: Atezolizumab338 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT01810913·Phase 2, Phase 3·RecruitingApply to this trial
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexiafor Advanced Colorectal Carcinoma225 locations incl. Fort SmithSponsor: University of RochesterSex: All·Age: 18+Code: NCT06073431·RecruitingApply to this trial
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Studyfor Muscle Invasive Bladder Urothelial Carcinoma211 locations incl. Fort SmithSponsor: NRG OncologySex: All·Age: 18+Code: NCT07097142·Phase 3·RecruitingApply to this trial
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancerfor Prostate Adenocarcinoma402 locations incl. BirminghamSponsor: NRG OncologySex: Male·Age: 18+Code: NCT05946213·Phase 3·RecruitingApply to this trial
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancerfor Hematopoietic and Lymphatic System Neoplasm190 locations incl. BirminghamSponsor: Children's Oncology GroupSex: Female·Age: Up to 39Code: NCT06513962·Phase 3·RecruitingApply to this trial
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistulafor Pancreatic Carcinoma118 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT06807437·Phase 3·RecruitingApply to this trial
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)for Lung Non-Small Cell Carcinoma248 locations incl. JonesboroSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT06116682·Phase 2·RecruitingApply to this trial
Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphomafor Diffuse Large B-Cell Lymphoma87 locations incl. TucsonSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT05633615·Phase 2·RecruitingApply to this trial
Project: Every Child for Younger Patients With Cancerfor Adrenal Gland Pheochromocytoma245 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: Up to 25Code: NCT02402244·RecruitingApply to this trial
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinomafor Endometrial AdenocarcinomaDrug: Ipilimumab137 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: Female·Age: 18+Code: NCT05112601·Phase 2·RecruitingApply to this trial
Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)for Recurrent T Acute Lymphoblastic Leukemia163 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 12+Code: NCT04315324·Phase 1, Phase 2·RecruitingApply to this trial
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcomafor Metastatic Malignant Neoplasm in the Lung219 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: Up to 50Code: NCT05235165·Phase 3·RecruitingApply to this trial
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCTfor Central Nervous System Nongerminomatous Germ Cell Tumor149 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: 3 - 29Code: NCT04684368·Phase 2·RecruitingApply to this trial
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)for Down SyndromeDrug: Nivolumab209 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 1 - 30Code: NCT04546399·Phase 2·RecruitingApply to this trial
Collection and Storage of Tissue and Blood Samples From Patients With Cancerfor Hematopoietic and Lymphatic System Neoplasm140 locations incl. BirminghamSponsor: National Cancer Institute LAOSex: All·Age: 2 Months+Code: NCT02474160·RecruitingApply to this trial
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancerfor Rectal Cancer105 locations incl. PhoenixSponsor: Canadian Cancer Trials GroupSex: All·Age: 18+Code: NCT06205485·Phase 3·RecruitingApply to this trial
Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavityfor Gastric Adenocarcinoma55 locations incl. IrvineSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT07001748·Phase 2, Phase 3·RecruitingApply to this trial
Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathyfor Malignant Solid Neoplasm36 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT05642611·Phase 3·RecruitingApply to this trial
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trialfor Metastatic Colorectal Carcinoma60 locations incl. BirminghamSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT05863195·Phase 3·RecruitingApply to this trial