Paid Clinical Trials in Grand Rapids, MI
As of July 2026, 413 paid clinical trials are recruiting in Grand Rapids, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Grand Rapids offers studies at sites including Corewell Health Grand Rapids Hospitals - Butterworth Hospital for conditions such as Colorectal Cancer, Advanced Solid Tumors, Advanced Solid Tumor, Ovarian Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Grand Rapids
Trials by drug in Grand Rapids
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Newly added in Grand Rapids
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
DBC-664 in Adult Patients With Solid Tumors
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
Phase 1 Study of a Self-amplifying RNA Vaccine (ITI-5000) in Stage 2-3 Triple Negative Breast Cancer
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
392 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Top Research Study Locations in Grand Rapids
Researchers run research studies in Grand Rapids, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 59 |
| START Midwest | Colorectal Cancer, Advanced Solid Tumor, Endometrial Cancer | 57 |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 51 |
| Corewell Health | Amblyopia, Large B-cell Lymphoma, Non-Hodgkin Lymphoma | 41 |
| Trinity Health Grand Rapids Hospital | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8 | 40 |
| Helen DeVos Children's Hospital | Cystic Fibrosis, Focal Segmental Glomerulosclerosis, ATRT Recurrent | 16 |
| BAMF Health | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Prostate Cancer | 9 |
| Helen DeVos Children's Hospital at Spectrum Health | Muscular Atrophy, Spinal, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| START Midwest, LLC | Advanced Solid Tumors, Advanced Breast Cancer, Advanced NRAS-Mutant Melanoma | 8 |
| Spectrum Health at Butterworth Campus | Metastatic Malignant Neoplasm in the Brain, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 8 |
| South Texas Accelerated Research Therapeutics (START) Midwest | Advanced Solid Tumors, Colorectal Cancer, Colorectal Carcinoma | 7 |
| Cancer and Hematology Centers of Western Michigan | Diffuse Large B-cell Lymphoma (DLBCL), Metastatic Breast Cancer, Metastatic Colorectal Cancer | 7 |
| Corewell Health West | Angina Pectoris, Atrial Fibrillation, Chest Pain | 5 |
| Spectrum Health | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 5 |
| The Cancer & Hematology Centers | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Colonic Diseases | 4 |
| Foundation for Vision Research | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 4 |
| GSK Investigational Site | Breast Neoplasms, Multiple Myeloma, Neoplasms | 4 |
| START - Midwest | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 4 |
| The Cancer and Hematology Centers | B Cell Lymphoma, Chronic Lymphocytic Leukemia, Extra-Pancreatic Neuroendocrine Tumor (epNET) | 4 |
| Cancer & Hematology Centers of Western Michigan | Bladder Carcinoma, Breast Cancer, Cutaneous Melanoma | 4 |
| BAMF Health Inc. | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 3 |
| Pediatric Ophthalmology, P.C. | Amblyopia | 3 |
| Spectrum Health Medical Group | Bladder Cancer, Cardiovascular Diseases, Connective Tissue Diseases | 3 |
| Cancer And Hematology Centers of Western Michigan PC | Colorectal Neoplasms, Multiple Myeloma | 2 |
| Corewell Health (Spectrum) | Aortic Aneurysm, Abdominal, Aortic Stenosis | 2 |
Active & Upcoming Studies in Grand Rapids (2026)
Recruiting trials in Grand Rapids grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (223 active studies)
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
- Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE) · Phase 2, Phase 3 · GE Healthcare
Cardiovascular (20 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Neurology & pain (10 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- Clinical Evaluation of Radiation Reduction for Optimized Safety · Angiowave Imaging
Eye & vision (6 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Mental health & behavior (5 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (5 active studies)
Pediatric (2 active studies)
- PURSUIT: A Technologically Augmented School-based Program to Improve Child Coping and Prevent Substance Use. · Michigan State University
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in Grand Rapids
- Colorectal Cancer (16 active studies)
- Advanced Solid Tumors (14 active studies)
- Advanced Solid Tumor (11 active studies)
- Ovarian Cancer (10 active studies)
- Breast Cancer (9 active studies)
- Endometrial Cancer (9 active studies)
Leading research sponsors in Grand Rapids
- National Cancer Institute (NCI)
- Children's Oncology Group
- SWOG Cancer Research Network
- AstraZeneca
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Grand Rapids?
There are approximately 413 recruiting clinical trials in Grand Rapids, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Grand Rapids pay participants?
Most recruiting trials in Grand Rapids compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Grand Rapids?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Grand Rapids?
The most common conditions under active study in Grand Rapids include Colorectal Cancer (16), Advanced Solid Tumors (14), Advanced Solid Tumor (11), Ovarian Cancer (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Grand Rapids?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Grand Rapids on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Grand Rapids?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Grand Rapids?
Recruiting research sites in Grand Rapids include Corewell Health Grand Rapids Hospitals - Butterworth Hospital, START Midwest, Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Grand Rapids right now?
The largest active categories in Grand Rapids are Cancer & tumors (223), Cardiovascular (20), Neurology & pain (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.