Clinical Trials at M D Anderson Cancer Center

As of August 2026, 259 paid clinical trials are recruiting at M D Anderson Cancer Center, located at 1515 HOLCOMBE BLVD, UNIT 1445, HOUSTON, TX 77030-4000, phone (713) 745-0496 in Houston, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

259 clinical trials at M D Anderson Cancer Center

·Clear filters·

A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients

for Pulmonary Hemorrhage

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05053867·Phase 3·Recruiting·Listed Sep 2021

Apply to this trial

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

for Advanced Breast Carcinoma

Drug: Cabozantinib

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05092373·Phase 1·Recruiting·Listed Oct 2021

Apply to this trial

Hypofractionated Radiation Therapy for Merkel Cell Carcinoma

for Merkel Cell Carcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05100095·Phase 2·Recruiting·Listed Oct 2021

Apply to this trial

The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts

for Breast Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 30 - 75

Code: NCT05667532·Recruiting·Listed Dec 2022

Apply to this trial

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

for Metastatic Solid Tumor

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05673928·Phase 2·Recruiting·Listed Jan 2023

Apply to this trial

Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases

for Melanoma (Skin)

Drug: Relatlimab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05704647·Phase 2·Recruiting·Listed Jan 2023

Apply to this trial

Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical Resection

for Pancreatic Cyst

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05873699·Phase 1·Recruiting·Listed May 2023

Apply to this trial

Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancers

for Gland

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05884320·Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

A Randomized Trial of Maintenance Systemic Therapy After Radiation for Oligometastatic Renal Cell Carcinoma (ASTROs)

for Oligometastatic Renal Cell Carcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06004336·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

for T Acute Lymphoblastic Leukemia

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: All ages

Code: NCT00501826·Phase 2·Recruiting·Listed Jul 2007

Apply to this trial

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

for Malignant Head and Neck Neoplasm

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT01365169·Recruiting·Listed Jun 2011

Apply to this trial

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia With t(9

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT01371630·Phase 1, Phase 2·Recruiting·Listed Jun 2011

Apply to this trial

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

for Clinical Stage 0 Cutaneous Melanoma AJCC v8

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03819296·Phase 1·Recruiting·Listed Jan 2019

Apply to this trial

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

for IDH1 wt Allele

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03896568·Phase 1·Recruiting·Listed Apr 2019

Apply to this trial

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

for Colitis

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04038619·Phase 1·Recruiting·Listed Jul 2019

Apply to this trial

NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial

for Prostate Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06066437·Phase 1, Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma

for Multiple Myeloma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06105554·Phase 1, Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

for Liver Metastases

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05062317·Phase 2·Recruiting·Listed Sep 2021

Apply to this trial

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

for Hematopoietic and Lymphoid Cell Neoplasm

Drug: Ruxolitinib

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 12 - 80

Code: NCT04744116·EARLY_Phase 1·Recruiting·Listed Feb 2021

Apply to this trial

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Houston, Austin +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

Apply to this trial

A Pilot Presurgical Trial of REGN5678 (Anti-PSMA x CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy

for Prostate Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT06085664·Phase 1, Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors

for Cranial Nerve Disorder

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04151082·Phase 1, Phase 2·Recruiting·Listed Nov 2019

Apply to this trial

Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study

for Ovarian Cancer

Sites in Houston +8 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT05287451·Recruiting·Listed Mar 2022

Apply to this trial

Data Collection Protocol for Patients With Von Hippel Lindau Disease

for Von Hippel Lindau Disease

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05955014·Recruiting·Listed Jul 2023

Apply to this trial

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in Houston, Austin +67 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

Apply to this trial

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Houston +145 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

for Prostate Carcinoma

Drug: Niraparib

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT04947254·Phase 2·Recruiting·Listed Jul 2021

Apply to this trial

Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

for Breast Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05774678·Phase 3·Recruiting·Listed Mar 2023

Apply to this trial

Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100

for Ovarian Clear Cell Carcinoma

Drug: Dostarlimab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06065462·Phase 1, Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

for Aplastic Anemia

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT01624805·Phase 2·Recruiting·Listed Jun 2012

Apply to this trial

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

for Colorectal Adenocarcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04739072·Recruiting·Listed Feb 2021

Apply to this trial

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

for Breast Carcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT00991094·Recruiting·Listed Oct 2009

Apply to this trial

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

for Acquired Immunodeficiency Syndrome

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: All ages

Code: NCT02479698·Phase 2·Recruiting·Listed Jun 2015

Apply to this trial

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for Acute Myeloid Leukemia

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04047641·Phase 1, Phase 2·Recruiting·Listed Aug 2019

Apply to this trial

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for Acute Myeloid Leukemia With Gene Mutations

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04493164·Phase 2·Recruiting·Listed Jul 2020

Apply to this trial

Canakinumab for the Prevention of Lung Cancer, the Can-Prevent-Lung Trial

for Lung Carcinoma

Drug: Canakinumab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04789681·Phase 2·Recruiting·Listed Mar 2021

Apply to this trial

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

for Gliomas

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT05804227·EARLY_Phase 1·Recruiting·Listed Apr 2023

Apply to this trial

Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer

for Prostate Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT05873192·Phase 2·Recruiting·Listed May 2023

Apply to this trial

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

for Hematopoietic and Lymphoid Cell Neoplasm

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06184321·EARLY_Phase 1·Recruiting·Listed Dec 2023

Apply to this trial

Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia

for Hairy Cell Leukemia

Drug: Rituximab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT00412594·Phase 2·Recruiting·Listed Dec 2006

Apply to this trial