Paid Clinical Trials in Iowa

Iowa has 757 paid clinical trials enrolling now across cities including Iowa City, Des Moines and Waukee. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

700 clinical trials

Get a weekly email when new trials open in Iowa City, IA.

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for Mitral Valve Regurgitation

Sites in Des Moines +66 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18+

Code: NCT03242642·Recruiting·Listed Aug 2017

Apply to this trial

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for Endometrial Adenocarcinoma

Sites in Iowa City +41 more locations

Sponsor: Acrivon Therapeutics

Sex: Female·Age: 18+

Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022

Apply to this trial

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

Sites in Iowa City +36 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

Sites in Iowa City +31 more locations

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for AML

Sites in Iowa City +35 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06001788·Phase 1·Recruiting·Listed Aug 2023

Apply to this trial

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

for B-cell Malignancy

Sites in Iowa City +27 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

Sites in Iowa City +40 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting·Listed Dec 2024

Apply to this trial

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

Sites in Iowa City +36 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for Upper Urinary Tract Urothelial Carcinoma

Sites in Clive +30 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT06774131·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

for Prostate Cancer

Sites in Iowa City +36 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT06855277·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: TAK-279

Sites in Iowa City +25 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024

Apply to this trial

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Sites in Iowa City +27 more locations

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

Sites in Iowa City, West Des Moines +29 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting·Listed Jan 2019

Apply to this trial

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

Sites in Iowa City +43 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting·Listed Feb 2024

Apply to this trial

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

Sites in Iowa City +39 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting·Listed Jul 2025

Apply to this trial

SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

Sites in Iowa City +63 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting·Listed Jul 2023

Apply to this trial

Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

Sites in Iowa City +73 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting·Listed Oct 2005

Apply to this trial

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

Sites in Iowa City +23 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting·Listed Mar 2023

Apply to this trial

Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

Sites in Iowa City +73 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

Apply to this trial

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

Sites in Des Moines +49 more locations

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting·Listed Sep 2024

Apply to this trial

Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

Sites in Iowa City +31 more locations

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting·Listed Mar 2023

Apply to this trial

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for Carcinoma, Non-Small-Cell Lung

Sites in Iowa City +24 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05208762·Phase 1·Recruiting·Listed Jan 2022

Apply to this trial

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

Sites in West Des Moines +157 more locations

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in Iowa City +61 more locations

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT06617325·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Sites in Iowa City +132 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting·Listed May 2024

Apply to this trial

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

Sites in Iowa City +137 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting·Listed Mar 2024

Apply to this trial

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for Relapsing Multiple Sclerosis

Sites in Iowa City +38 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT05877963·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

Sites in Waukee +93 more locations

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT06767514·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

Sites in Iowa City +56 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting·Listed Jul 2024

Apply to this trial

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for NASH With Fibrosis

Drug: Efruxifermin

Sites in West Des Moines +172 more locations

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06215716·Phase 3·Recruiting·Listed Jan 2024

Apply to this trial

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

for Refractory Rheumatoid Arthritis (RA)

Drug: Rituximab

Sites in Iowa City +30 more locations

Sponsor: Artiva Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06991114·Phase 2·Recruiting·Listed May 2025

Apply to this trial

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

Sites in Iowa City, Des Moines +69 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

Apply to this trial

The THOR IDE Study

for Peripheral Artery Disease

Sites in Davenport +28 more locations

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting·Listed Jun 2023

Apply to this trial

A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

Sites in Iowa City +31 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting·Listed Oct 2023

Apply to this trial

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

Sites in Iowa City +34 more locations

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting·Listed Nov 2021

Apply to this trial

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

Sites in West Des Moines +132 more locations

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting·Listed Feb 2023

Apply to this trial

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Iowa City +37 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

Sites in Iowa City, Waukee +29 more locations

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

Sites in Iowa City +32 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting·Listed Jan 2023

Apply to this trial

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

Sites in Iowa City +42 more locations

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial