Paid Clinical Trials in Iowa

Iowa has 761 paid clinical trials enrolling now across cities including Iowa City, Des Moines and Waukee. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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701 clinical trials

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for HR+ Breast Cancer

Sites in Iowa City +17 more locations

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07029399·Phase 1·Recruiting·Listed Jun 2025

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Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

Sites in Iowa City +16 more locations

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting·Listed Dec 2024

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A Study of ASP1002 in Adults for Treatment of Solid Tumors

for Advanced Solid Tumors

Sites in Iowa City +11 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05719558·Phase 1·Recruiting·Listed Feb 2023

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A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

for Solid Malignancies

Sites in Iowa City +16 more locations

Sponsor: Immunome, Inc.

Sex: All·Age: 18+

Code: NCT06823167·Phase 1·Recruiting·Listed Feb 2025

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A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

for Advanced Lung Cancer

Sites in Iowa City +15 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06892548·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

Sites in Iowa City +16 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting·Listed Jul 2025

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A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

Sites in Iowa City +14 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting·Listed Jun 2025

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Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

for Gastric or Gastroesophageal Junction Adenocarcinoma

Sites in Iowa City +9 more locations

Sponsor: Phanes Therapeutics

Sex: All·Age: 18+

Code: NCT05482893·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

for Malignant Neoplasm

Sites in Iowa City +16 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 Month - 17

Code: NCT06941272·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

Sites in Iowa City +15 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06948318·Phase 3·Recruiting·Listed Apr 2025

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Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

for Central Line Associated Blood Stream Infections (CLABSI)

Sites in Iowa City +15 more locations

Sponsor: CorMedix

Sex: All·Age: 18+

Code: NCT06822426·Phase 3·Recruiting·Listed Feb 2025

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Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for B-cell Acute Lymphoblastic Leukemia

Sites in Iowa City +16 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 6 Months - 25

Code: NCT06395103·Phase 1, Phase 2·Recruiting·Listed May 2024

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

Sites in Iowa City +19 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting·Listed Jun 2021

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

Sites in Iowa City +12 more locations

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 74

Code: NCT07085104·Phase 1·Recruiting·Listed Jul 2025

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

Sites in Iowa City +21 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting·Listed Sep 2023

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A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

Sites in Iowa City +16 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06722235·Phase 3·Recruiting·Listed Dec 2024

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A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

for Thrombocytopenia, Neonatal Alloimmune

Drug: Nipocalimab

Sites in Iowa City +11 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT06533098·Phase 3·Recruiting·Listed Aug 2024

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

Sites in Iowa City +21 more locations

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

Sites in Iowa City +14 more locations

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting·Listed Sep 2023

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A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

for Lung Cancer

Sites in Iowa City +11 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06618287·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

Sites in Iowa City +10 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting·Listed Jun 2021

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MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

for Recurrent Melanoma (Skin)

Drug: Nivolumab

Sites in Iowa City +11 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05655312·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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Hydrus® Microstent New Enrollment Post-Approval Study

for Primary Open Angle Glaucoma

Sites in Sioux City +19 more locations

Sponsor: Alcon Research

Sex: All·Age: 45+

Code: NCT04553523·Recruiting·Listed Sep 2020

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STOP AF First Post-Approval Study

for Paroxysmal Atrial Fibrillation

Sites in West Des Moines +9 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT05227053·Recruiting·Listed Feb 2022

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A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

for SLE

Sites in Iowa City +9 more locations

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT06613360·Phase 1·Recruiting·Listed Sep 2024

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A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy

for Primary Membranous Nephropathy

Sites in Iowa City +18 more locations

Sponsor: Cerium Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05696613·Phase 3·Recruiting·Listed Jan 2023

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A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for Cervical Cancer

Sites in Iowa City +8 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT04895709·Phase 1, Phase 2·Recruiting·Listed May 2021

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Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

for IgAN

Sites in Iowa City +10 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06989359·Phase 2·Recruiting·Listed May 2025

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A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Waukee +20 more locations

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06588478·Phase 2·Recruiting·Listed Sep 2024

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Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

Sites in Iowa City +15 more locations

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting·Listed Mar 2025

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A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

for Chronic Kidney Disease

Drug: Finerenone

Sites in Iowa City +13 more locations

Sponsor: Bayer

Sex: All·Age: 6 Months - 17

Code: NCT05196035·Phase 3·Recruiting·Listed Jan 2022

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A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

for Lupus Erythematosus, Systemic

Sites in Iowa City +18 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06581198·Phase 2·Recruiting·Listed Sep 2024

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A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for Urothelial Carcinoma Bladder

Sites in Iowa City +11 more locations

Sponsor: Aktis Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07020117·Phase 1·Recruiting·Listed Jun 2025

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A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

for Pemphigus Vulgaris

Sites in Iowa City +9 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18+

Code: NCT04422912·Phase 1, Phase 2·Recruiting·Listed Jun 2020

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Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

for Adult Acute Myeloid Leukemia

Sites in Iowa City +12 more locations

Sponsor: Priothera SAS

Sex: All·Age: 18 - 75

Code: NCT05429632·Phase 3·Recruiting·Listed Jun 2022

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A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

for Spinal Muscular Atrophy

Drug: Apitegromab

Sites in Iowa City +13 more locations

Sponsor: Scholar Rock, Inc.

Sex: All·Age: Up to 2

Code: NCT07047144·Phase 2·Recruiting·Listed Jul 2025

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Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

for PDAC

Sites in Iowa City +17 more locations

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06922591·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

for C3G

Drug: Iptacopan

Sites in Iowa City +4 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT04817618·Phase 3·Recruiting·Listed Mar 2021

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A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

Sites in Iowa City +21 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting·Listed Oct 2024

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Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

Sites in Iowa City +13 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial