Paid Clinical Trials in Iowa

Iowa has 757 paid clinical trials enrolling now across cities including Iowa City, Des Moines and Waukee. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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700 clinical trials

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A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

for Primary Immune Thrombocytopenia (ITP)

Sites in Iowa City +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06544499·Phase 3·Recruiting·Listed Aug 2024

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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

for Peripheral T-Cell Lymphoma, Not Otherwise Specified

Drug: Soquelitinib

Sites in Iowa City +20 more locations

Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06561048·Phase 3·Recruiting·Listed Aug 2024

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A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia

Drug: Revumenib

Sites in Iowa City +9 more locations

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 30 Days+

Code: NCT04065399·Phase 1, Phase 2·Recruiting·Listed Aug 2019

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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

for Ulcerative Colitis

Sites in Iowa City +20 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06975722·Phase 2·Recruiting·Listed May 2025

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A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor Malignancies

Sites in Iowa City +14 more locations

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06994806·Phase 1·Recruiting·Listed May 2025

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Pompe Pregnancy Sub-Registry

for Glycogen Storage Disease Type II (GSD-II)

Sites in Iowa City +13 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: Female·Age: All ages

Code: NCT00567073·Recruiting·Listed Dec 2007

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

Sites in Iowa City +19 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting·Listed Dec 2023

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A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

Sites in Iowa City +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting·Listed Mar 2024

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A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

for Crohn's Disease

Sites in Iowa City +19 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06958536·Phase 2·Recruiting·Listed May 2025

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A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

for Epilepsy, Temporal Lobe

Sites in Iowa City +15 more locations

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06422923·Phase 1, Phase 2·Recruiting·Listed May 2024

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Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

for Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

Sites in Iowa City +21 more locations

Sponsor: Servier Bio-Innovation LLC

Sex: All·Age: 18+

Code: NCT06127407·Phase 3·Recruiting·Listed Nov 2023

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

Sites in Iowa City +23 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting·Listed Aug 2023

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Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

for Duchenne Muscular Dystrophy

Drug: Givinostat

Sites in Iowa City +1 more location

Sponsor: Italfarmaco

Sex: Male·Age: 7+

Code: NCT03373968·Phase 2, Phase 3·Recruiting·Listed Dec 2017

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Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

for Metastatic Breast Cancer

Drug: Palazestrant

Sites in Iowa City +13 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05508906·Phase 1·Recruiting·Listed Aug 2022

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Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

for Acute Ischemic Stroke From Large Vessel Occlusion

Sites in Iowa City +10 more locations

Sponsor: Anaconda Biomed S.L.

Sex: All·Age: 22 - 85

Code: NCT06370182·Recruiting·Listed Apr 2024

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A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

Sites in Iowa City +23 more locations

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting·Listed Jun 2024

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A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

for Overactive Bladder

Sites in Iowa City, Ankeny +17 more locations

Sponsor: Valencia Technologies Corporation

Sex: All·Age: 18+

Code: NCT05685433·Recruiting·Listed Jan 2023

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Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

Sites in Iowa City +7 more locations

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting·Listed Aug 2021

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MB-105 in Patients With CD5 Positive T-cell Lymphoma

for Lymphoma, T-Cell

Sites in Iowa City +11 more locations

Sponsor: March Biosciences Inc

Sex: All·Age: 18+

Code: NCT06534060·Phase 2·Recruiting·Listed Aug 2024

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Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare

for Acute Gouty Arthritis

Sites in Des Moines +13 more locations

Sponsor: Atom Therapeutics Co., Ltd

Sex: All·Age: 18 - 70

Code: NCT07145229·Phase 2·Recruiting·Listed Aug 2025

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Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

Sites in Iowa City +12 more locations

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Iowa City +21 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

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A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)

for Malignant Neoplasm

Sites in Iowa City +11 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 Month - 17

Code: NCT07630974·Phase 1, Phase 2·Recruiting·Listed Jun 2026

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A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma

for Histologically Confirmed Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Sites in Iowa City +5 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT07439653·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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Study of Intrathecal ELP-02 for Charcot-Marie-Tooth Disease Type 4J (CMT4J)

for Charcot-Marie-Tooth Disease Type 4J

Sites in Iowa City +1 more location

Sponsor: Elpida Therapeutics SPC

Sex: All·Age: 3 - 20

Code: NCT07447557·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

for Hemophilia A

Drug: NXT007

Sites in Iowa City +5 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 12+

Code: NCT07416604·Phase 3·Recruiting·Listed Feb 2026

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Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in Cedar Rapids +9 more locations

Sponsor: Airiver Medical, Inc.

Sex: All·Age: 18+

Code: NCT07290140·Recruiting·Listed Dec 2025

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A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

Sites in Iowa City +5 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 18+

Code: NCT07287150·Phase 2·Recruiting·Listed Dec 2025

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A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

for Diabetes Mellitus, Type 1

Drug: Baricitinib

Sites in Iowa City, West Des Moines +5 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 35

Code: NCT07222137·Phase 3·Recruiting·Listed Oct 2025

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A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

for Haemophilia A

Sites in Iowa City +4 more locations

Sponsor: Novo Nordisk A/S

Sex: Male·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07220564·Phase 1·Recruiting·Listed Oct 2025

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A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

for Acute Myeloid Leukaemia (AML)

Sites in Iowa City +9 more locations

Sponsor: Tempus AI

Sex: All·Age: 0+

Code: NCT07154823·Recruiting·Listed Sep 2025

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EVERO Drug-coated Balloon (DCB) Randomized Trial

for Peripheral Vascular Disease

Sites in Davenport +8 more locations

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT07144150·Recruiting·Listed Aug 2025

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A Study to Assess the Effects of Zigakibart on IgA Nephropathy.

for Immunoglobulin A Nephropathy (IgAN)

Sites in Iowa City +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07146906·Phase 2·Recruiting·Listed Aug 2025

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Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

for Small Cell Lung Carcinoma

Sites in Iowa City +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07006727·Phase 1·Recruiting·Listed Jun 2025

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

for Hemophilia A

Drug: NXT007

Sites in Iowa City +2 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 2 - 59

Code: NCT05987449·Phase 1, Phase 2·Recruiting·Listed Aug 2023

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Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

for Hereditary Transthyretin-mediated (hATTR) Amyloidosis

1 location in Iowa City

Sponsor: Alnylam Pharmaceuticals

Sex: Female·Age: All ages

Code: NCT05040373·Recruiting·Listed Sep 2021

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A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

for SLE (Systemic Lupus)

Sites in Iowa City +8 more locations

Sponsor: CRISPR Therapeutics

Sex: All·Age: 18 - 70

Code: NCT06925542·Phase 1·Recruiting·Listed Apr 2025

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An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

for Friedreich Ataxia

Sites in Iowa City +5 more locations

Sponsor: Larimar Therapeutics, Inc.

Sex: All·Age: 2 - 60

Code: NCT06447025·Phase 2·Recruiting·Listed Jun 2024

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Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1

for Radiation-Induced Xerostomia and Hyposalivation

Sites in Iowa City +3 more locations

Sponsor: RiboX Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06714253·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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FastWire REvascularisation of Extremities, (For LOWer Limbs) - FREEFLOW

for Chronic Total Occlusion of Artery of the Extremities

Sites in Davenport +5 more locations

Sponsor: Versono Medical Ltd

Sex: All·Age: 18 - 85

Code: NCT06492733·Recruiting·Listed Jul 2024

Apply to this trial