Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

Sites in Chicago +15 more locations

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 74

Code: NCT07085104·Phase 1·Recruiting·Listed Jul 2025

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A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Sites in Chicago +11 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07008118·Phase 1·Recruiting·Listed Jun 2025

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A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

for Aortic Aneurysm

Sites in Chicago +14 more locations

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT07078383·Recruiting·Listed Jul 2025

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Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

for Hyperkalemia

Drug: patiromer

Sites in Peoria +10 more locations

Sponsor: Vifor Pharma, Inc.

Sex: All·Age: 0 - 11

Code: NCT05766839·Phase 2·Recruiting·Listed Mar 2023

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

Sites in Chicago +19 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting·Listed Jun 2021

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BoxX-NoAF Clinical Trial

for Post Operative Atrial Fibrillation

Sites in Chicago +23 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06989775·Recruiting·Listed May 2025

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A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies

for NSCLC

Drug: EP0031

Sites in Evanston +14 more locations

Sponsor: Ellipses Pharma

Sex: All·Age: 18+

Code: NCT05443126·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for Atrial Fibrillation (AF)

Sites in Springfield +17 more locations

Sponsor: Arga Medtech SA

Sex: All·Age: 18 - 80

Code: NCT06784466·Recruiting·Listed Jan 2025

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4D-710 in Adult Patients With Cystic Fibrosis

for Cystic Fibrosis Lung

Sites in Chicago +17 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 18+

Code: NCT05248230·Phase 2·Recruiting·Listed Feb 2022

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PULSED AF Post-Approval Study

for Atrial Fibrillation

Sites in Chicago +15 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT06578104·Recruiting·Listed Aug 2024

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A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: Remibrutinib

Sites in Chicago +23 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT06744920·Phase 3·Recruiting·Listed Dec 2024

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An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

for Recurrent Pericarditis

Sites in Chicago +13 more locations

Sponsor: Zomagen Biosciences Ltd.

Sex: All·Age: 18 - 75

Code: NCT06836232·Phase 2·Recruiting·Listed Feb 2025

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A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

for Immune Thrombocytopenia (ITP)

Sites in Peoria +10 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06721013·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for Gastric Adenocarcinoma

Sites in Chicago +9 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05365581·Phase 1·Recruiting·Listed May 2022

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A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

for Diffuse Cutaneous Systemic Sclerosis

Drug: Ianalumab

Sites in Chicago +15 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06470048·Phase 2·Recruiting·Listed Jun 2024

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Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

for Down Syndrome

Sites in Chicago +11 more locations

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+

Code: NCT01429389·Recruiting·Listed Sep 2011

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A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)

for Von Willebrand Disease (VWD)

Sites in Peoria +11 more locations

Sponsor: Takeda

Sex: All·Age: Up to 17

Code: NCT05582993·Phase 3·Recruiting·Listed Oct 2022

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Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for Severe Hypertriglyceridemia

Drug: Plozasiran

Sites in Springfield +16 more locations

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06880770·Phase 3·Recruiting·Listed Mar 2025

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A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

Sites in Rolling Meadows +15 more locations

Sponsor: Inmagene LLC

Sex: All·Age: 18 - 74

Code: NCT07037901·Phase 2·Recruiting·Listed Jun 2025

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A Study of JNT-517 in Participants With Phenylketonuria (PKU)

for Phenylketonuria

Sites in Chicago +9 more locations

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18+

Code: NCT06971731·Phase 3·Recruiting·Listed May 2025

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Cephea Early Feasibility Study

for Mitral Regurgitation

Sites in Chicago +19 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT05061004·Recruiting·Listed Sep 2021

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A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for Acromegaly

Sites in Chicago +9 more locations

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06930625·Phase 3·Recruiting·Listed Apr 2025

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

Sites in Chicago +23 more locations

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting·Listed Dec 2016

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Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

for AMI Cardiogenic Shock

Sites in Peoria +17 more locations

Sponsor: Abiomed Inc.

Sex: All·Age: 18+

Code: NCT06964685·Recruiting·Listed May 2025

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A Study of LY4175408 in Participants With Advanced Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY4175408

Sites in Chicago +14 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07046923·Phase 1·Recruiting·Listed Jul 2025

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A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

for Duchenne Muscular Dystrophy

Sites in Chicago +11 more locations

Sponsor: Solid Biosciences Inc.

Sex: Male·Age: 0 - 17

Code: NCT06138639·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

for Ovarian Cancer

Drug: Cemiplimab

Sites in Chicago +11 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT04590326·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

for Relapsed/Refractory Acute Myeloid Leukemia

Sites in Chicago +17 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT06714591·Phase 1·Recruiting·Listed Dec 2024

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STRIVE Post-Market Registry Study

for Emphysema

Sites in Chicago +15 more locations

Sponsor: Olympus Corporation of the Americas

Sex: All·Age: 18+

Code: NCT04302272·Recruiting·Listed Mar 2020

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A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

for Dravet Syndrome

Sites in Chicago +10 more locations

Sponsor: Encoded Therapeutics

Sex: All·Age: 6 Months - 17

Code: NCT05419492·Phase 1, Phase 2·Recruiting·Listed Jun 2022

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RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

for Systemic Sclerosis

Sites in Chicago +9 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 75

Code: NCT06328777·Phase 2, Phase 3·Recruiting·Listed Mar 2024

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Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for Non-Small Cell Lung Cancer

Drug: Bevacizumab

Sites in Chicago +19 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05005403·Phase 1·Recruiting·Listed Aug 2021

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A Study of ZL-1310 in Participants With Selected Solid Tumors

for Solid Tumors

Sites in Peoria +11 more locations

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06885281·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

for Parenteral Nutrition Associated Liver Disease (PNALD)

Sites in Chicago +9 more locations

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Day - 17

Code: NCT06274788·Recruiting·Listed Feb 2024

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MEASuRE: Metreleptin Effectiveness And Safety Registry

for Generalised Lipodystrophy

Sites in Chicago +8 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: All ages

Code: NCT02325674·Recruiting·Listed Dec 2014

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

Sites in Peoria +11 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT06332534·Phase 3·Recruiting·Listed Mar 2024

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

Sites in Chicago, Park Ridge +13 more locations

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting·Listed Sep 2023

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A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

for Acute Pancreatitis

Sites in Chicago +9 more locations

Sponsor: Panafina, Inc.

Sex: All·Age: 18 - 85

Code: NCT06080789·Phase 2·Recruiting·Listed Oct 2023

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Chicago, Lisle +21 more locations

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

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A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sites in Chicago +23 more locations

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting·Listed Nov 2024

Apply to this trial