Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

for Depressive Disorder, Major

Sites in Evanston +9 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 12 - 17

Code: NCT07227454·Phase 3·Recruiting·Listed Nov 2025

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A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia

for Patients With Chemotherapy-Induced Thrombocytopenia

Sites in Springfield +6 more locations

Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: All·Age: 18+

Code: NCT07286032·Phase 3·Recruiting·Listed Dec 2025

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A Prospective Trial of a Variable Compression System for Moderate to Severe Irritable Bowel Syndrome

for IBS (Irritable Bowel Syndrome)

Sites in Bolingbrook +2 more locations

Sponsor: PGP Health

Sex: All·Age: 18 - 60

Code: NCT07540312·Recruiting·Listed Apr 2026

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A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer (NSCLC)

Sites in Peoria +9 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07140016·Phase 1·Recruiting·Listed Aug 2025

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TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

for Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy

Drug: Nucresiran

Sites in Chicago +9 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07223203·Phase 3·Recruiting·Listed Oct 2025

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A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

for Muscular Atrophy, Spinal

Sites in Chicago +2 more locations

Sponsor: Biogen

Sex: All·Age: 0 Days - 42 Days

Code: NCT07221669·Phase 3·Recruiting·Listed Oct 2025

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Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)

for Alcohol Use Disorder

Sites in Chicago +7 more locations

Sponsor: Brainsway

Sex: All·Age: 18 - 86

Code: NCT07216872·Recruiting·Listed Oct 2025

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A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

for Schizophrenia

Drug: KarXT

Sites in Chicago +7 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 55

Code: NCT07061288·Phase 1·Recruiting·Listed Jul 2025

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Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

for Breast Neoplasms

Sites in Skokie +7 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06797635·Phase 2·Recruiting·Listed Jan 2025

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A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Sites in Oak Forest +5 more locations

Sponsor: Complement Therapeutics

Sex: All·Age: 55+

Code: NCT07144137·Recruiting·Listed Aug 2025

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A Study of CTD402 in T-ALL/LBL Patients

for Acute Lymphocytic Leukemia Refractory

Sites in Chicago +6 more locations

Sponsor: Imviva Bio

Sex: All·Age: 1+

Code: NCT07070219·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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COPD Exacerbation Follow Up

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Park Ridge +4 more locations

Sponsor: Viz.ai, Inc.

Sex: All·Age: 40+

Code: NCT07118306·Recruiting·Listed Aug 2025

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A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

for Post Traumatic Arthritis

Sites in Morton Grove +4 more locations

Sponsor: Stryker Trauma and Extremities

Sex: All·Age: 21+

Code: NCT07118501·Recruiting·Listed Aug 2025

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A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment

for Wrinkle

Sites in Chicago +6 more locations

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 30 - 60·Accepts healthy volunteers

Code: NCT07187297·Recruiting·Listed Sep 2025

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Falcon Real World Evidence Registry

for Cancer

Sites in Evanston +1 more location

Sponsor: Exact Sciences Corporation

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06589310·Recruiting·Listed Sep 2024

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A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort

for Duchenne Muscular Dystrophy

Sites in Chicago +10 more locations

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: 2+

Code: NCT04626674·Phase 1·Recruiting·Listed Nov 2020

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A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for Metastatic Hepatocellular Carcinoma

Drug: Bevacizumab

Sites in Zion +6 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06427941·Phase 1, Phase 2·Recruiting·Listed May 2024

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A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

for Advanced Prostate Cancer

Sites in Chicago +4 more locations

Sponsor: Genentech, Inc.

Sex: Male·Age: 18+

Code: NCT05800665·Phase 1·Recruiting·Listed Apr 2023

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Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS

for Short Bowel Syndrome

Sites in Chicago +4 more locations

Sponsor: Zealand Pharma

Sex: All·Age: 18 - 90

Code: NCT07197944·Phase 3·Recruiting·Listed Sep 2025

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Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

for Unresectable or Metastatic Hepatocellular Carcinoma

Drug: Nivolumab

Sites in Peoria +2 more locations

Sponsor: CatalYm GmbH

Sex: All·Age: 18 - 100

Code: NCT07219459·Phase 2·Recruiting·Listed Oct 2025

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Lateral Plantar Artery Embolization For Plantar Fasciitis

for Plantar Fasciitis, Chronic

1 location in Libertyville

Sponsor: Joint & Vascular Institute

Sex: All·Age: 25 - 80

Code: NCT07395128·Phase 1·Recruiting·Listed Feb 2026

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Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators

for X-Linked Myotubular Myopathy

Sites in Chicago +3 more locations

Sponsor: Astellas Gene Therapies

Sex: Male·Age: Up to 36 Months

Code: NCT07052929·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

for Age-Related Macular Degeneration

Sites in Lemont +6 more locations

Sponsor: i-Lumen Scientific AUS PTY LTD

Sex: All·Age: 60+

Code: NCT06662162·Recruiting·Listed Oct 2024

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A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

for Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

Sites in Chicago +7 more locations

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT05765812·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

for Systemic Sclerosis (SSc)

Drug: Efgartigimod PH20 SC

Sites in Chicago +8 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06655155·Phase 2·Recruiting·Listed Oct 2024

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A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

for Sickle Cell Disease

Sites in Chicago +7 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT07187973·Phase 1·Recruiting·Listed Sep 2025

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Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome

for Pitt Hopkins Syndrome

Sites in Chicago +2 more locations

Sponsor: Mahzi Therapeutics

Sex: All·Age: 2 - 25

Code: NCT07135050·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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An External Control Arm Study in Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

Sites in Barrington, Rolling Meadows +6 more locations

Sponsor: N-Power Medicine

Sex: All·Age: 18+

Code: NCT07174388·Recruiting·Listed Sep 2025

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A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition

for X-Linked Myotubular Myopathy

Sites in Chicago +6 more locations

Sponsor: Astellas Gene Therapies

Sex: Male·Age: Up to 17

Code: NCT06581146·Recruiting·Listed Sep 2024

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SMP-3124LP in Adults With Advanced Solid Tumors

for Solid Tumor

Sites in Chicago +9 more locations

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06526819·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

for Ulcerative Colitis

Sites in Chicago +7 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06979336·Phase 2·Recruiting·Listed May 2025

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Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria

for Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU)

Drug: Remibrutinib

Sites in Glenview +1 more location

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06865651·Phase 2·Recruiting·Listed Mar 2025

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A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

for Small Cell Lung Cancer

Drug: Gocatamig

Sites in Chicago +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06780137·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

for Low Back Pain

Sites in Chicago, Evanston +8 more locations

Sponsor: Aclarion

Sex: All·Age: 18 - 70

Code: NCT06661850·Recruiting·Listed Oct 2024

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Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

for Juvenile Psoriatic Arthritis

Drug: Secukinumab

Sites in Chicago +10 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06751238·Phase 1·Recruiting·Listed Dec 2024

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Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for Weight Regain

Sites in Chicago +8 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07015424·Recruiting·Listed Jun 2025

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JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency

for SHANK3 Haploinsufficiency

Sites in Chicago +2 more locations

Sponsor: Jaguar Gene Therapy, LLC

Sex: All·Age: 2 - 9

Code: NCT06662188·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex

for Epidermolysis Bullosa Simplex

Sites in Chicago +1 more location

Sponsor: BioMendics, LLC

Sex: All·Age: 2+

Code: NCT07027345·Phase 2·Recruiting·Listed Jun 2025

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Mucopolysaccharidosis VII Disease Monitoring Program

for Mucopolysaccharidosis VII

Sites in Chicago +5 more locations

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: All ages

Code: NCT03604835·Recruiting·Listed Jul 2018

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A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

for Glioblastoma Multiforme

Sites in Chicago +6 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT05303467·Phase 1·Recruiting·Listed Mar 2022

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