Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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Development of a Home Test for Measuring Blood P-tau217 in Alzheimer's Disease Using the Tasso Lancet Device

for Alzheimer s Disease

1 location in Chicago

Sponsor: Neurogen Biomarking LLC

Sex: All·Age: 40 - 90·Accepts healthy volunteers

Code: NCT07701161·Recruiting·Listed Jul 2026

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A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Ascending Doses of ABBV-1451 Infusions and Injections in Healthy Adult Participants

for Healthy Volunteer

1 location in Grayslake

Sponsor: AbbVie

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07570147·Phase 1·Recruiting·Listed May 2026

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Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

for Relapsed or Refractory Large B-cell Lymphoma

Sites in Zion +13 more locations

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT07479797·Phase 3·Recruiting·Listed Mar 2026

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A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

for Muscle-invasive Bladder Cancer

Sites in Chicago, Lisle +10 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07475806·Phase 2·Recruiting·Listed Mar 2026

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Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

for Schizophrenia

Drug: GXV813

Sites in Chicago +6 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07467993·Phase 2·Recruiting·Listed Mar 2026

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Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC

for Carcinoma

Drug: PF-08634404

Sites in New Lenox, Hinsdale +5 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07489066·Phase 2·Recruiting·Listed Mar 2026

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Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With Achondroplasia

for Achondroplasia

Drug: Vosoritide

Sites in Chicago +8 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 17

Code: NCT07441876·Phase 2, Phase 3·Recruiting·Listed Mar 2026

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Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in New Lenox, Hinsdale +2 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07476287·Phase 2·Recruiting·Listed Mar 2026

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A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

for Ocular Myasthenia Gravis

Sites in O'Fallon +4 more locations

Sponsor: UCB Biopharma SRL

Sex: All·Age: 18+

Code: NCT07463521·Phase 3·Recruiting·Listed Mar 2026

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A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

for Glioblastoma Multiforme of Brain

Sites in Chicago +2 more locations

Sponsor: Tetragon Biosciences Ltd

Sex: All·Age: 18+

Code: NCT07464925·Phase 1·Recruiting·Listed Mar 2026

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A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

for Primary Immune Thrombocytopenia (ITP)

Drug: Ianalumab

Sites in Hinsdale +12 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07421167·Phase 2·Recruiting·Listed Feb 2026

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A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Peoria, Niles +14 more locations

Sponsor: BioNTech SE

Sex: Male·Age: 18+

Code: NCT07365995·Phase 3·Recruiting·Listed Jan 2026

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AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

Sites in Zion +6 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07403721·Phase 1·Recruiting·Listed Feb 2026

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A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.

for Non Small Cell Lung Cancer (Squamous or Non Squamous)

Sites in Peoria +15 more locations

Sponsor: Eikon Therapeutics

Sex: All·Age: 18+

Code: NCT07365319·Phase 2, Phase 3·Recruiting·Listed Jan 2026

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An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease

for Thyroid Eye Disease

Sites in Orland Park +3 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07438405·Phase 2·Recruiting·Listed Feb 2026

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Study of the Progression of Chronic Cardiovascular Conditions

for Cardiovascular Disease (CVD)

1 location in Chicago

Sponsor: Prolaio

Sex: All·Age: 18+

Code: NCT07420907·Recruiting·Listed Feb 2026

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A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV

for HIV -1 Infection

Drug: BNT351

Sites in Chicago +3 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07392372·Phase 1·Recruiting·Listed Feb 2026

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A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for Advanced Solid Tumor, Adult

Sites in Chicago +14 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07361562·Phase 1·Recruiting·Listed Jan 2026

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Aspiration Thrombectomy Using the Symphony or Prodigy System

for Arterial Thromboembolism

Sites in Naperville +7 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07350499·Recruiting·Listed Jan 2026

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A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for FGFR2 Gene Fusion/Rearrangement

Drug: Lirafugratinib

Sites in Chicago +7 more locations

Sponsor: Elevar Therapeutics

Sex: All·Age: 18+

Code: NCT07359820·Phase 2·Recruiting·Listed Jan 2026

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ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

for CLL / SLL

Sites in Skokie +5 more locations

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 18+

Code: NCT07342478·Phase 3·Recruiting·Listed Jan 2026

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Achilles Tendinopathy Embolization

for Achilles Tendinopathy (AT)

1 location in Libertyville

Sponsor: Joint & Vascular Institute

Sex: All·Age: 25 - 80

Code: NCT07477860·Phase 1·Recruiting·Listed Mar 2026

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A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

for Pulmonary Hypertension

Sites in Chicago +12 more locations

Sponsor: Pulmovant, Inc.

Sex: All·Age: 18 - 85

Code: NCT07333183·Phase 2·Recruiting·Listed Jan 2026

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Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea

for Diarrhea

Sites in Island Lake +9 more locations

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 6 - 12

Code: NCT07285785·Phase 4·Recruiting·Listed Dec 2025

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A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD

for Pulmonary Hypertension Due to Lung Disease (Disorder)

Sites in Chicago +11 more locations

Sponsor: Liquidia Technologies, Inc.

Sex: All·Age: 18 - 80

Code: NCT07285655·Phase 3·Recruiting·Listed Dec 2025

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Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for Lymphoma Diffuse Large B-cell

Sites in Chicago, Evanston +3 more locations

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284433·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Flow Detection in Open and Closed Shunt Valve Periods

for Hydrocephalus

1 location in Peoria

Sponsor: Rhaeos, Inc.

Sex: All·Age: All ages

Code: NCT07478926·Recruiting·Listed Mar 2026

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A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Chicago, Zion +19 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

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geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry

for Knee Osteoarthristis

1 location in Libertyville

Sponsor: Joint & Vascular Institute

Sex: All·Age: 18+

Code: NCT07380906·Recruiting·Listed Feb 2026

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A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity

for Obesity

Sites in Grayslake +1 more location

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT07291232·Phase 1·Recruiting·Listed Dec 2025

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U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

for Bone Tumor

Sites in Chicago +2 more locations

Sponsor: Precision IO Group

Sex: All·Age: 22+

Code: NCT07325578·Recruiting·Listed Jan 2026

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A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)

for Lung Neoplasm Malignant

Sites in Chicago +3 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07286149·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

for Duchenne Muscular Dystrophy

Sites in Chicago +6 more locations

Sponsor: Satellos Bioscience, Inc.

Sex: Male·Age: 7 - 9

Code: NCT07287189·Phase 2·Recruiting·Listed Dec 2025

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Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

Sites in Champaign +9 more locations

Sponsor: AbbVie

Sex: All·Age: 40+

Code: NCT07230288·Phase 2·Recruiting·Listed Nov 2025

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A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Bevacizumab in Adult Participants With Ovarian Cancer

for Ovarian Cancer

Drug: Bevacizumab

Sites in Chicago +4 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07278336·Phase 1·Recruiting·Listed Dec 2025

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An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM)

for Indolent Systemic Mastocytosis

Sites in Normal +6 more locations

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07264959·Recruiting·Listed Dec 2025

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A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for Advanced Squamous Tumors

Sites in Chicago +5 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07241039·Phase 1·Recruiting·Listed Nov 2025

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xDot Access Management System Early Feasibility Study

for Vascular Closure Devices

Sites in Downers Grove +4 more locations

Sponsor: xDot Medical, Inc

Sex: All·Age: 18+

Code: NCT07464353·Recruiting·Listed Mar 2026

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Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)

for Long QT Syndrome (LQTS) 2

Sites in Chicago +8 more locations

Sponsor: Thryv Therapeutics, Inc.

Sex: All·Age: 15+

Code: NCT07277582·Phase 2, Phase 3·Recruiting·Listed Dec 2025

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KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for Bladder Cancer

Sites in Chicago +3 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07232602·Phase 1, Phase 2·Recruiting·Listed Nov 2025

Apply to this trial