Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

for Alcohol Drinking

2 locations in Champaign

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 21 - 30·Accepts healthy volunteers

Code: NCT07125534·Recruiting·Listed Aug 2025

Apply to this trial

CBTi for the Treatment of Insomnia in Type 1 Diabetes

for Diabetes Mellitus Type 1

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 65

Code: NCT07091318·EARLY_Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

Sites in Chicago +51 more locations

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting·Listed Apr 2012

Apply to this trial

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

for Nephrolithiasis

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06635889·Phase 2·Recruiting·Listed Oct 2024

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rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

for Prostate Adenocarcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT05852041·EARLY_Phase 1·Recruiting·Listed May 2023

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Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

for Tachycardia Atrial

1 location in Oak Lawn

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06376916·Phase 3·Recruiting·Listed Apr 2024

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Evaluating Evidenced Based Options for PTSD Treatment

for PTSD - Post Traumatic Stress Disorder

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06733376·Recruiting·Listed Dec 2024

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A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease

for Liver Diseases

Sites in Chicago +3 more locations

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05733832·Recruiting·Listed Feb 2023

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Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset

for PTSD

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 70

Code: NCT05700279·Recruiting·Listed Jan 2023

Apply to this trial

Nasal Antisepsis for C. Auris Prevention

for Candida Auris Infection

Sites in Chicago & Hinsdale

Sponsor: Mary K Hayden

Sex: All·Age: 18+

Code: NCT06282510·Phase 4·Recruiting·Listed Feb 2024

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Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer

for Urothelial Carcinoma

1 location in Chicago

Sponsor: Tampere University Hospital

Sex: All·Age: 18 - 100

Code: NCT06310759·Recruiting·Listed Mar 2024

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Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy (PRONTO-EYE)

for Diabetic Retinopathy (DR)

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07296952·Recruiting·Listed Dec 2025

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

Sites in Chicago, Peoria +54 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting·Listed Feb 2013

Apply to this trial

Angelman Syndrome Natural History Study

for Angelman Syndrome

Sites in Chicago +7 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT04507997·Recruiting·Listed Aug 2020

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Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer

for Endometrial Clear Cell Adenocarcinoma

Sites in Maywood +2 more locations

Sponsor: University of Utah

Sex: All·Age: All ages

Code: NCT03422198·Phase 3·Recruiting·Listed Feb 2018

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WIM Exosuit Wearable Soft Robot for Enhancing Walking Activity

for Stroke

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT07061691·Recruiting·Listed Jul 2025

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Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

for Elderly

2 locations in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 70+

Code: NCT06824818·Recruiting·Listed Feb 2025

Apply to this trial

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

for Sickle Cell Disease

Sites in Chicago +8 more locations

Sponsor: RTI International

Sex: All·Age: 18+

Code: NCT06385886·Recruiting·Listed Apr 2024

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Technology-Enhanced Asthma Care in Children at Clinic and Home Study

for Asthma in Children

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4+·Accepts healthy volunteers

Code: NCT06820593·Recruiting·Listed Feb 2025

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Comprehensive Geriatric Assessment (Tests) for Bladder Cancer Participants Undergoing Radical Cystectomy

for Bladder Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 65+

Code: NCT06427824·Recruiting·Listed May 2024

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American Joint Replacement Registry

for ARTHROPLASTY, REPLACEMENT

1 location in Rosemont

Sponsor: American Joint Replacement Registry

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01909375·Recruiting·Listed Jul 2013

Apply to this trial

Ketamine as a Supplement to Local Anesthesia for Minor Procedures

for Pain, Procedural

1 location in Maywood

Sponsor: Loyola University

Sex: All·Age: 7 - 70

Code: NCT06284473·Phase 4·Recruiting·Listed Feb 2024

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Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

for Gastric Cancers

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: All ages

Code: NCT01416714·Recruiting·Listed Aug 2011

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Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

for Premature

Sites in Chicago +6 more locations

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: Up to 36 Weeks

Code: NCT05380401·Recruiting·Listed May 2022

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Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

for Adenoid Cystic Carcinoma

Sites in Chicago +4 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04883671·Recruiting·Listed May 2021

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Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

for Ventricular Tachycardia

Sites in Chicago +4 more locations

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06138873·Recruiting·Listed Nov 2023

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Studying Health Outcomes After Treatment in Patients With Retinoblastoma

for Retinoblastoma

Sites in Chicago +9 more locations

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03932786·Recruiting·Listed May 2019

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Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans

for Chronic Pain

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05094297·Recruiting·Listed Oct 2021

Apply to this trial

Vocal Emotion Communication With Cochlear Implants

for Cochlear Hearing Loss

Sites in Evanston +3 more locations

Sponsor: Father Flanagan's Boys' Home

Sex: All·Age: 6 - 80·Accepts healthy volunteers

Code: NCT05486637·EARLY_Phase 1·Recruiting·Listed Aug 2022

Apply to this trial

Foundation for Sarcoidosis Research Advanced Cures Registry (FSR-SARC Registry)

for Sarcoidosis

1 location in Chicago

Sponsor: Foundation for Sarcoidosis Research

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT06234384·Recruiting·Listed Jan 2024

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Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry

for Vasovagal Syncope

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 60

Code: NCT06166277·Recruiting·Listed Dec 2023

Apply to this trial

Prognostic Estimates Among ICU Clinicians

for Mechanical Ventilation

Sites in Chicago +1 more location

Sponsor: Rush University Medical Center

Sex: All·Age: All ages

Code: NCT06452797·Recruiting·Listed Jun 2024

Apply to this trial

Get Fit for Function

for Thoracic

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06359652·Recruiting·Listed Apr 2024

Apply to this trial

Combining Biomarkers and Electronic Risk Scores to Predict AKI in Hospitalized Patients

for Acute Kidney Injury

Sites in Chicago +1 more location

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT05988658·Recruiting·Listed Aug 2023

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Genetics of Cardiovascular and Neuromuscular Disease

for Cardiomyopathy

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: All ages

Code: NCT00138931·Recruiting·Listed Aug 2005

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A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation

for Transfemoral Amputation

1 location in Chicago

Sponsor: VA Office of Research and Development

Sex: All·Age: 45 - 75

Code: NCT06218238·Recruiting·Listed Jan 2024

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Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

for Urothelial Carcinoma

Sites in Springfield +3 more locations

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 19+

Code: NCT06262516·Recruiting·Listed Feb 2024

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Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer

for Prostate Cancer

Sites in Warrenville +3 more locations

Sponsor: Proton Collaborative Group

Sex: Male·Age: 18+

Code: NCT01492972·Phase 3·Recruiting·Listed Dec 2011

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Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss

for Depression, Anxiety

1 location in Chicago

Sponsor: The Chicago Lighthouse

Sex: All·Age: 18+

Code: NCT07073521·Recruiting·Listed Jul 2025

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Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

for Atrial Fibrillation (AF)

Sites in Evanston +5 more locations

Sponsor: McMaster University

Sex: All·Age: 18+

Code: NCT06957366·Recruiting·Listed May 2025

Apply to this trial