Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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Selumetinib and Azacitidine in High Risk Chronic Blood Cancers

for Chronic Myeloid Leukemia

Drug: Selumetinib

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT03326310·Phase 1·Recruiting·Listed Oct 2017

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Inpatient Stroke Recovery Using Sensors

for Stroke

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04219670·Recruiting·Listed Jan 2020

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Type 1 Diabetes and Obstructive Sleep Apnea

for Sleep Apnea, Obstructive

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 50

Code: NCT06915831·Recruiting·Listed Apr 2025

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Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

for Multiple Myeloma

Drug: Belantamab mafodotin

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT05789303·Phase 2·Recruiting·Listed Mar 2023

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Biobank Cardiac Surgery

for Cardiovascular Diseases

1 location in Hyde Park

Sponsor: University of Chicago

Sex: All·Age: All ages

Code: NCT06747806·Recruiting·Listed Dec 2024

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BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer

for Breast Cancer

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT06085742·Phase 2·Recruiting·Listed Oct 2023

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Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD

for Multiple Myeloma

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05192122·Phase 1·Recruiting·Listed Jan 2022

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Rare and Atypical Diabetes Network

for Diabetes Mellitus

Sites in Chicago +12 more locations

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting·Listed Sep 2022

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Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

for Corneal Ulcer

Sites in Chicago +1 more location

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05705024·Phase 2·Recruiting·Listed Jan 2023

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Social Cognition Training in Individuals With Huntington's Disease

for Huntington&#39

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 65

Code: NCT06828471·Recruiting·Listed Feb 2025

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Immune Status After Being on Call for 24 Hrs

for Sleep Deprivation

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06636318·Recruiting·Listed Oct 2024

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Islet Transplantation in Patients With "Brittle" Type I Diabetes

for Diabetes Mellitus, Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT01630850·Recruiting·Listed Jun 2012

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Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

for Elevated Serum PSA

Sites in Chicago +2 more locations

Sponsor: University of Chicago

Sex: Male·Age: 18 - 80

Code: NCT05512754·Phase 4·Recruiting·Listed Aug 2022

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Islet Transplantation in Type 1 Diabetic Kidney Allograft

for Diabetes Mellitus, Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 68

Code: NCT01241864·Phase 2·Recruiting·Listed Nov 2010

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Blood Flow Restriction Following Hip Arthroscopy

for Labral Tear, Glenoid

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT04113759·Recruiting·Listed Oct 2019

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Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Aflibercept

Sites in Chicago +3 more locations

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06121180·Phase 2·Recruiting·Listed Nov 2023

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IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 Antibodies

for Small Fiber Neuropathy

1 location in Glenview

Sponsor: Endeavor Health

Sex: All·Age: 18+

Code: NCT04153422·Phase 2·Recruiting·Listed Nov 2019

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Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device

for Multiple Sclerosis

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT06410261·Recruiting·Listed May 2024

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Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

for Breast Cancer

Sites in Warrenville +8 more locations

Sponsor: Proton Collaborative Group

Sex: Female·Age: 50+

Code: NCT01766297·Phase 2·Recruiting·Listed Jan 2013

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Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

for Pancreatic Cancer

Sites in Warrenville +2 more locations

Sponsor: Proton Collaborative Group

Sex: All·Age: 18+

Code: NCT02598349·Phase 2·Recruiting·Listed Nov 2015

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COPD Resources, Education, and Activity Designed for You Study

for COPD

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 40+

Code: NCT07125053·Recruiting·Listed Aug 2025

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Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

for Relapsed Adult AML

Sites in Evanston +19 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05237258·Recruiting·Listed Feb 2022

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Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

for Head and Neck Neoplasms

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06912087·Phase 1·Recruiting·Listed Apr 2025

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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

for Heart Failure

Drug: Finerenone

Sites in Peoria +53 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06033950·Phase 3·Recruiting·Listed Sep 2023

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UIC Multi-Ethnic DCM Registry

for Heart Failure

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07145138·Recruiting·Listed Aug 2025

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Auricular Acupressure in Prehabilitation

for Frailty

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 50+

Code: NCT06516198·Recruiting·Listed Jul 2024

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Stress Hydrocortisone In Pediatric Septic Shock

for Septic Shock

Sites in Chicago, Peoria +16 more locations

Sponsor: Jerry Zimmerman

Sex: All·Age: 1 Month - 17

Code: NCT03401398·Phase 3·Recruiting·Listed Jan 2018

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Implementation of Population Cancer Genetic Services in Federally Qualified Health Centers (FQHC)

for Hereditary Cancer Syndrome

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 25+

Code: NCT05664867·Recruiting·Listed Dec 2022

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Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study

for Wheezing

2 locations in Chicago

Sponsor: Rajesh Kumar

Sex: All·Age: 2 Months - 12 Months·Accepts healthy volunteers

Code: NCT05667701·Phase 2·Recruiting·Listed Dec 2022

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The Use of CCK vs PS in Revision TKAs

for Aseptic Loosening of Prosthetic Joint

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06782295·Phase 4·Recruiting·Listed Jan 2025

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Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss

for Traumatic Amputation of Lower Extremity

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05929508·Recruiting·Listed Jul 2023

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Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

for Spinal Cord Injury

Sites in Hines +6 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06529094·Recruiting·Listed Jul 2024

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Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation

for Overweight or Obesity

Drug: Semaglutide

Sites in Chicago +1 more location

Sponsor: University of Chicago

Sex: All·Age: 18 - 75

Code: NCT06499857·Phase 3·Recruiting·Listed Jul 2024

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Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

for Stage IV NSCLC

Sites in Chicago +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06671613·Recruiting·Listed Nov 2024

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Quantitative Assessment of Autologous Fat Transfer

for Autologous Fat Grafting

Sites in Chicago +1 more location

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06343831·Recruiting·Listed Apr 2024

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A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

for COVID-19

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06008860·Phase 4·Recruiting·Listed Aug 2023

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Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery

for Colorectal Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06349590·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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NSAID Use for Treating Dysmenorrhea and Preventing Chronic Pelvic Pain (NSAID HEAL)

for Dysmenorrhea

1 location in Evanston

Sponsor: Endeavor Health

Sex: Female·Age: 18 - 35

Code: NCT06861920·Phase 4·Recruiting·Listed Mar 2025

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Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections

for Acute Otitis Media

Sites in Chicago +2 more locations

Sponsor: Intermountain Health Care, Inc.

Sex: All·Age: 6 Months - 17

Code: NCT06034080·Recruiting·Listed Sep 2023

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Improving Mobility After Revascularization in Peripheral Artery Disease

for Peripheral Artery Disease

Sites in Chicago +6 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06686121·Phase 3·Recruiting·Listed Nov 2024

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