Paid Clinical Trials in Illinois

Illinois has 2,971 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 22, 2026.

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2,971 clinical trials

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Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

3 locations incl. Chicago

Sponsor: argenx

Sex: All·Age: 2 - 18

Code: NCT04833894·Phase 2, Phase 3·Recruiting

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An Individualized-health eLibrary App for People With Multiple Sclerosis

for Multiple Sclerosis

1 location in Champaign

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 18+

Code: NCT05124600·Recruiting

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A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for Metastatic Colorectal Cancer

35 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04929223·Phase 1·Recruiting

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Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

for Bipolar I Disorder

14 locations incl. Dothan

Sponsor: Alkermes, Inc.

Sex: All·Age: 10 - 17

Code: NCT04987229·Phase 3·Enrolling By Invitation

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

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Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

for Tuberous Sclerosis Complex

11 locations incl. Birmingham

Sponsor: Darcy Krueger

Sex: All·Age: 1 Day - 6 Months

Code: NCT05104983·Phase 2·Recruiting

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

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STRIVE Post-Market Registry Study

for Emphysema

14 locations incl. Phoenix

Sponsor: Olympus Corporation of the Americas

Sex: All·Age: 18+

Code: NCT04302272·Recruiting

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Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans

for Chronic Pain

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05094297·Recruiting

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A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

10 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

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A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

for Relapsed/Refractory Multiple Myeloma

Drug: Daratumumab

16 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT04973605·Phase 1, Phase 2·Recruiting

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Precision-Based Genomics in Prostate Cancer

for Prostate Cancer

11 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT04706663·Recruiting

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Dual Task Perturbation Training for OAwMCI

for Mild Cognitive Impairment

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT04938349·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

11 locations incl. Washington D.C.

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting

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Longitudinal Studies to Identify Biomarkers for Sturge-Weber Syndrome

for Sturge-Weber Syndrome

8 locations incl. San Francisco

Sponsor: University of Illinois at Chicago

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04717427·Recruiting

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A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire Clinical Trial)

for Canavan Disease

4 locations incl. Oakland

Sponsor: Aspa Therapeutics

Sex: All·Age: Up to 30 Months

Code: NCT04998396·Phase 1, Phase 2·Recruiting

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SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

14 locations incl. Birmingham

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting

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Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

28 locations incl. Laguna Hills

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting

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PROspective Study of Mothers' and Infants' Social and Epidemiologic Determinants of Health

for Infertility, Female

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18 - 44·Accepts healthy volunteers

Code: NCT05358483·Recruiting

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Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

for Carcinoma, Non-Small Cell Lung

Drug: Osimertinib

10 locations incl. Los Angeles

Sponsor: Genprex, Inc.

Sex: All·Age: 18+

Code: NCT04486833·Phase 1, Phase 2·Recruiting

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AnovaOS Network Powered Patient Registry

for Infectious Disease

1 location in Arlington Heights

Sponsor: Anova Enterprises, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05013944·Recruiting

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

10 locations incl. Aurora

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting

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Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

13 locations incl. Phoenix

Sponsor: Michael Pulsipher

Sex: All·Age: 0 - 25

Code: NCT04836390·Phase 2·Enrolling By Invitation

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

10 locations incl. Little Rock

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting

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A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

for Adenovirus Infections

11 locations incl. Los Angeles

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT04706923·Phase 2·Recruiting

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Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

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Reducing Opioid Mortality in Illinois

for Opioid Use

5 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04925427·Recruiting

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Mitral Valve Screening Survey

for Mitral Valve Disease

14 locations incl. Phoenix

Sponsor: Medstar Health Research Institute

Sex: All·Age: 18+

Code: NCT04736667·Recruiting

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IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

for Endometrial Cancer

24 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05051722·Recruiting

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

20 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting

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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

for Adult Spinal Deformity

12 locations incl. Phoenix

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04885244·Recruiting

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Zimmer Biomet Shoulder Arthroplasty PMCF

for Shoulder Fractures

12 locations incl. Irvine

Sponsor: Zimmer Biomet

Sex: All·Age: 20+

Code: NCT04984291·Recruiting

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EFS of the CardioMech MVRS

for Mitral Regurgitation

12 locations incl. Thousand Oaks

Sponsor: CardioMech AS

Sex: All·Age: 18+

Code: NCT04820764·Recruiting

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