Clinical Trials at Riley Hospital for Children

As of July 2026, 59 paid clinical trials are recruiting at Riley Hospital for Children, located at 702 BARNHILL DR, SUITE 2500, INDIANAPOLIS, IN 46202-5128, phone (317) 948-4949 in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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60 clinical trials at Riley Hospital for Children

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Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

Sites in Indianapolis +51 more locations

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Precise Infliximab Exposure and Pharmacodynamic Control

for Crohn Disease

Sites in Indianapolis +10 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6 - 22

Code: NCT05660746·Phase 2, Phase 3·Recruiting·Listed Dec 2022

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Indianapolis +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

Sites in Indianapolis +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting·Listed Feb 2024

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Supraglottic Airway for Resuscitation Trial

for Neonatal Resuscitation

Sites in Indianapolis +29 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 Days+

Code: NCT07150923·Recruiting·Listed Sep 2025

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Indianapolis +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Indianapolis +144 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for Diffuse Midline Glioma, H3 K27-Altered

Sites in Indianapolis +33 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 21

Code: NCT04870944·Phase 1, Phase 2·Recruiting·Listed May 2021

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Clinical Decision Support Tool in PARDS Pilot Study

for Ventilation Therapy

Sites in Indianapolis +5 more locations

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 1 Month - 18

Code: NCT04068012·Recruiting·Listed Aug 2019

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Indianapolis +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Use of Eye Tracking to Aid in Autism Risk Detection

for Autism

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 12 Months - 48 Months

Code: NCT06471504·Recruiting·Listed Jun 2024

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

Sites in Indianapolis +20 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Indianapolis +21 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

Sites in Indianapolis +50 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting·Listed Jul 2015

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Indianapolis +67 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

Sites in Indianapolis +39 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting·Listed Mar 2016

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Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

for Constipation

Sites in Indianapolis & Carmel

Sponsor: Indiana University

Sex: All·Age: 2 - 18·Accepts healthy volunteers

Code: NCT05821309·Phase 4·Recruiting·Listed Apr 2023

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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

Sites in Indianapolis +28 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting·Listed Jul 2022

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Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients

for Coagulopathy

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 3 Months - 18

Code: NCT05874843·Recruiting·Listed May 2023

Apply to this trial