Paid Clinical Trials in Indianapolis, IN

As of September 2026, 881 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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779 clinical trials

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A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for Type 1 Diabetes

Drug: Adalimumab

Sites in Indianapolis +9 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 9 - 20

Code: NCT07061574·Phase 1, Phase 2·Recruiting·Listed Jul 2025

Apply to this trial

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

for Cardiac Arrest, Out-Of-Hospital

Sites in Indianapolis +48 more locations

Sponsor: University of Michigan

Sex: All·Age: 2 Days - 17

Code: NCT05376267·Recruiting·Listed May 2022

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PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Indianapolis +30 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting·Listed Sep 2024

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Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

Sites in Indianapolis +23 more locations

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting·Listed Mar 2025

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

Sites in Indianapolis, Carmel +56 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting·Listed May 2025

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Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

for Glioblastoma

Sites in Indianapolis +10 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06934889·Phase 1·Recruiting·Listed Apr 2025

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Measuring Patient Reported Needs in Outpatient Liver Disease Management

for Chronic Liver Disease

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07191886·Recruiting·Listed Sep 2025

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

Sites in Indianapolis +9 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting·Listed Aug 2025

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

Sites in Indianapolis +101 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting·Listed May 2022

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

Sites in Indianapolis +39 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05338697·Recruiting·Listed Apr 2022

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Indianapolis +79 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

Sites in Indianapolis +20 more locations

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting·Listed May 2023

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

Sites in Indianapolis +18 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting·Listed Oct 2023

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Indianapolis +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2

for Post Operative Surgical Site Infection

Sites in Indianapolis +30 more locations

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting·Listed Dec 2020

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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Sites in Indianapolis, Carmel +39 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18+

Code: NCT05646316·Phase 3·Recruiting·Listed Dec 2022

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Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

for Recurrent World Health Organization (WHO) Grade II Glioma

Drug: Trametinib

Sites in Indianapolis +14 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 25

Code: NCT04485559·Phase 1·Recruiting·Listed Jul 2020

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De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

for Congenital Diaphragmatic Hernia

Sites in Indianapolis +18 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 Months - 1 Month

Code: NCT05213676·Phase 4·Recruiting·Listed Jan 2022

Apply to this trial

Spine Oncology Registry

for Spine Tumor

Sites in Indianapolis +4 more locations

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07225491·Recruiting·Listed Nov 2025

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Indianapolis +163 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

Sites in Indianapolis +9 more locations

Sponsor: Naga P. Chalasani

Sex: All·Age: 18+

Code: NCT07143968·Phase 2·Recruiting·Listed Aug 2025

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Indianapolis +21 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

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Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

for Chronic Pancreatitis

Sites in Indianapolis +2 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04996628·Recruiting·Listed Aug 2021

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Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)

for PPAP

Sites in Indianapolis +4 more locations

Sponsor: Senthil Sadhasivam

Sex: All·Age: 10 - 21

Code: NCT05367609·Recruiting·Listed May 2022

Apply to this trial

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

Sites in Indianapolis +24 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting·Listed Apr 2020

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Indianapolis +112 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

for Acute Stress Reaction

Sites in Indianapolis +8 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 55

Code: NCT06636786·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Indianapolis +65 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

Apply to this trial

Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias

for Paroxysmal Atrial Fibrillation

Sites in Indianapolis +63 more locations

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT04088071·Recruiting·Listed Sep 2019

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

Sites in Indianapolis +17 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

Smart Pillows for Enhancing Sleep Quality

for Snoring

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 50+

Code: NCT06594627·Recruiting·Listed Sep 2024

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Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

for Drug-Drug Interaction

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05789173·EARLY_Phase 1·Recruiting·Listed Mar 2023

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

Sites in Indianapolis +30 more locations

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting·Listed Oct 2024

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A-LiNK: Improving Outcomes in Autoimmune Liver Disease

for Autoimmune Hepatitis

Sites in Indianapolis +7 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05750498·Recruiting·Listed Mar 2023

Apply to this trial

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

for Type 1 Diabetes

1 location in Indianapolis

Sponsor: Heba M. Ismail

Sex: All·Age: 11 - 18

Code: NCT05414409·Phase 2·Recruiting·Listed Jun 2022

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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

Sites in Indianapolis +34 more locations

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting·Listed Aug 2020

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

Sites in Indianapolis, Carmel +52 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

for Laryngeal Dystonia

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 70

Code: NCT05506085·Recruiting·Listed Aug 2022

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

Sites in Indianapolis, Valparaiso +586 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting·Listed May 2021

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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

Sites in Indianapolis +12 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06647498·Phase 2, Phase 3·Recruiting·Listed Oct 2024

Apply to this trial