Paid Clinical Trials in Indianapolis, IN

As of September 2026, 881 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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779 clinical trials

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A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

Sites in Indianapolis +12 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05552157·Phase 2, Phase 3·Recruiting·Listed Sep 2022

Apply to this trial

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

Sites in Indianapolis +58 more locations

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022

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Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery

for Skull Base Neoplasms

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05898074·Recruiting·Listed Jun 2023

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Indianapolis, Mooresville +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Indianapolis, Merrillville +80 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

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Increasing Equity in Lung Cancer Screening

for Lung Cancer

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06360822·Recruiting·Listed Apr 2024

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Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

for Cesarean Section Complications

Sites in Indianapolis +3 more locations

Sponsor: Senthil Sadhasivam

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05380531·Recruiting·Listed May 2022

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The Use of Body Surface Gastric Mapping in Assessing the Clinical Success of G-POEM

for Gastroparesis

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT06493032·Recruiting·Listed Jul 2024

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Fibrosis Lessens After Metabolic Surgery

for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)

Sites in Indianapolis +3 more locations

Sponsor: The Cleveland Clinic

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06374875·Phase 4·Recruiting·Listed Apr 2024

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Indianapolis +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers

for Metastatic Breast Cancer

Sites in Indianapolis, Carmel +5 more locations

Sponsor: Kathy Miller

Sex: All·Age: 18+

Code: NCT05846789·Phase 2·Recruiting·Listed May 2023

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HER2 Vaccine for Locally Advanced Breast Cancer

for Breast Cancer

1 location in Indianapolis

Sponsor: Pravin T.P Kaumaya

Sex: All·Age: 18+

Code: NCT06949410·Phase 1·Recruiting·Listed Apr 2025

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Letrozole in Uterine Leiomyosarcoma

for Uterine Leiomyosarcoma

Sites in Indianapolis +33 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05649956·Phase 2·Recruiting·Listed Dec 2022

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Denosumab for Type 1 Diabetes

for Type 1 Diabetes

Sites in Indianapolis +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50

Code: NCT06524960·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer

for Anal Cancer

Sites in Indianapolis +3 more locations

Sponsor: Dustin Deming

Sex: All·Age: 18+

Code: NCT06493019·Phase 2·Recruiting·Listed Jul 2024

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Follow-up Visit of High Risk Infants

for Infant, Newborn

Sites in Indianapolis +18 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 18 Months - 26 Months

Code: NCT00009633·Recruiting·Listed Feb 2001

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Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

Sites in Indianapolis +23 more locations

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting·Listed Nov 2021

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Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial

for Alcohol-associated Hepatitis

Sites in Indianapolis +5 more locations

Sponsor: Samer Gawrieh

Sex: All·Age: 18 - 70

Code: NCT07060638·Phase 2·Recruiting·Listed Jul 2025

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Indianapolis +75 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

Sites in Indianapolis +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting·Listed Jun 2025

Apply to this trial

SPARK Healthy Sleep

for Schizophrenia and Related Disorders

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07119268·Recruiting·Listed Aug 2025

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Indianapolis +380 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

for Breast Carcinoma

Sites in Indianapolis +3 more locations

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05557877·Phase 2·Recruiting·Listed Sep 2022

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Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

for Diabetes

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 65+

Code: NCT05643144·Recruiting·Listed Dec 2022

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Increasing Veterans' Social Engagement and Connectedness

for Social Isolation

1 location in Indianapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06467214·Recruiting·Listed Jun 2024

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Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

for Constipation

Sites in Indianapolis & Carmel

Sponsor: Indiana University

Sex: All·Age: 2 - 18·Accepts healthy volunteers

Code: NCT05821309·Phase 4·Recruiting·Listed Apr 2023

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Leg Heat Therapy in Peripheral Artery Disease

for Peripheral Artery Disease

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 50+

Code: NCT05465070·Recruiting·Listed Jul 2022

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Prevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between Factor VIII and Emicizumab Prophylaxis

for Hemophilia A

Sites in Indianapolis +9 more locations

Sponsor: Wayne State University

Sex: All·Age: 6 - 19

Code: NCT05022459·Recruiting·Listed Aug 2021

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Indianapolis +46 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in Indianapolis, Carmel +30 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

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ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx

for Squamous Cell Carcinoma of Oropharynx

Sites in Indianapolis & Carmel

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT06915038·Recruiting·Listed Apr 2025

Apply to this trial

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

Sites in Indianapolis +32 more locations

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting·Listed Sep 2023

Apply to this trial

The New Empowerment After eXposure to Trauma (NEXT) Study

for PTSD - Post Traumatic Stress Disorder

1 location in Indianapolis

Sponsor: Indiana University

Sex: Female·Age: 18 - 50

Code: NCT07175025·Recruiting·Listed Sep 2025

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Trifecta-Lung cfDNA-MMDx Study

for Lung Transplantation

Sites in Indianapolis +11 more locations

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT05837663·Recruiting·Listed May 2023

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Indianapolis, Mooresville +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

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The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients

for Ocular GVHD

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04700657·Recruiting·Listed Jan 2021

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Unilateral M1 Anodal tDCS to Enhance Learning in a Gross Movement Videogame Task

for Motor Activity

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07447882·Recruiting·Listed Mar 2026

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Indianapolis +35 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

Apply to this trial

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Sites in Indianapolis +240 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting·Listed Sep 2023

Apply to this trial

Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Indianapolis +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial