Paid Clinical Trials in Indianapolis, IN

As of September 2026, 881 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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779 clinical trials

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Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in Indianapolis +4 more locations

Sponsor: Matthew Galsky

Sex: All·Age: 18+

Code: NCT06809140·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Indianapolis +26 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients

for Coagulopathy

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 3 Months - 18

Code: NCT05874843·Recruiting·Listed May 2023

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Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections

for Methicillin Resistant Staphylococcus Aureus

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 2 Months - 18

Code: NCT06982105·Phase 4·Recruiting·Listed May 2025

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Embryonal Tumor With Multilayered Rosettes

for Embryonal Tumor With Multilayered Rosettes

Sites in Indianapolis +7 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06861244·Phase 2·Recruiting·Listed Mar 2025

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Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Plasma Insulin Levels

for Healthy

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06597149·Recruiting·Listed Sep 2024

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Options for Pain Management Using Nonpharmacological Strategies

for Pain

1 location in Indianapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05563792·Recruiting·Listed Oct 2022

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Hospital @ Home Model of Care for Cirrhosis

for Decompensated Cirrhosis

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT06396897·Recruiting·Listed May 2024

Apply to this trial

Telephone Support in Advanced Gastrointestinal Cancer

for Gastrointestinal Neoplasm Malignant

Sites in Indianapolis +3 more locations

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT06532877·Recruiting·Listed Aug 2024

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Preoperative Corticosteroids in Autoimmune Thyroid Disease

for Graves Disease

3 locations in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05435547·Phase 4·Recruiting·Listed Jun 2022

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Drug Interaction Potential of Pro-Inflammatory Conditions

for Diabetes Mellitus, Type 2

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 12 - 99

Code: NCT07360938·Recruiting·Listed Jan 2026

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Childhood Cancer Survivor Study

for Cancer

Sites in Indianapolis +26 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Indianapolis +242 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Bionic Pancreas in CFRD

for Cystic Fibrosis-related Diabetes

Sites in Indianapolis +14 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 14+

Code: NCT06449677·Phase 3·Recruiting·Listed Jun 2024

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Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension

for Food Insecurity

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 35 - 75

Code: NCT05856591·Recruiting·Listed May 2023

Apply to this trial

MIND Foods and Aerobic Training in Black Adults With HTN

for Cognitive Decline

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 35 - 75

Code: NCT06152614·Recruiting·Listed Nov 2023

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Biomarker of Diabetic Retinopathy

for Diabetic Retinopathy

Sites in Indianapolis & Carmel

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05079399·Recruiting·Listed Oct 2021

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Dominantly Inherited Alzheimer Network (DIAN)

for Alzheimer's Disease

Sites in Indianapolis +6 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00869817·Recruiting·Listed Mar 2009

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Improving Parental Support in Hypospadias Care

for Hypospadias

Sites in Indianapolis +1 more location

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: All ages

Code: NCT06832280·Recruiting·Listed Feb 2025

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Indianapolis +46 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

Sites in Indianapolis +35 more locations

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting·Listed May 2016

Apply to this trial

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Indianapolis +141 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

Apply to this trial

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

for Neuropathic Pain

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06420141·Recruiting·Listed May 2024

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Rapid Autopsy Protocol for Patients With Small Cell Lung Cancer

for Small Cell Lung Cancer

3 locations in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05889546·Recruiting·Listed Jun 2023

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Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

for Sickle Cell Disease (SCD)

Sites in Indianapolis +30 more locations

Sponsor: University of Rochester

Sex: All·Age: 3 - 20

Code: NCT06941389·Recruiting·Listed Apr 2025

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The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

for Extubation Failure

Sites in Indianapolis +15 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 9 Weeks

Code: NCT05446272·Recruiting·Listed Jul 2022

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Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes

for Gestational Diabetes

Sites in Indianapolis +4 more locations

Sponsor: Indiana University

Sex: Female·Age: 18 - 45

Code: NCT05124808·Recruiting·Listed Nov 2021

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Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

for Cancer

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05346796·Recruiting·Listed Apr 2022

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Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

for Small Cell Lung Cancer ( SCLC )

Drug: Lurbinectedin

1 location in Indianapolis

Sponsor: Misty Shields

Sex: All·Age: 18+

Code: NCT07153055·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

for Large Cell Lymphoma, Diffuse

Drug: Epcoritamab

Sites in Indianapolis +3 more locations

Sponsor: Dipenkumar Modi

Sex: All·Age: 18+

Code: NCT05852717·Phase 2·Recruiting·Listed May 2023

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Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

for Heterotaxy Syndrome

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: All ages

Code: NCT02432079·Recruiting·Listed May 2015

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To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.

for Type 1 Diabetes

1 location in Indianapolis

Sponsor: Viral N. Shah

Sex: All·Age: 18+

Code: NCT07287943·Recruiting·Listed Dec 2025

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Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

Sites in Indianapolis +7 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting·Listed Apr 2016

Apply to this trial

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

for Crohn Disease

Sites in Indianapolis +20 more locations

Sponsor: Connecticut Children's Medical Center

Sex: All·Age: 6 - 17

Code: NCT05781152·Phase 4·Recruiting·Listed Mar 2023

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Indianapolis +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

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Silk Bioprotein as a Wound Dressing for Double-Incision Mastectomy

for Wound Healing

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT06921148·Recruiting·Listed Apr 2025

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CD4CAR for CD4+ Leukemia and Lymphoma

for T-cell Lymphoma

Sites in Indianapolis +4 more locations

Sponsor: Huda Salman

Sex: All·Age: 12+

Code: NCT03829540·Phase 1·Recruiting·Listed Feb 2019

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Chimeric Antigen Receptor T Cell Therapy Redirected to CD4 (CD4CAR)as a Second Line Treatment for Chronic Myelomonocytic Leukemia, CMML.

for Chronic Myelomonocytic Leukemia

Sites in Indianapolis +3 more locations

Sponsor: Huda Salman

Sex: All·Age: 18+

Code: NCT06071624·Phase 1·Recruiting·Listed Oct 2023

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Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell Transplant

for Acute Myeloid Leukemia

Sites in Indianapolis +3 more locations

Sponsor: Huda Salman

Sex: All·Age: 12+

Code: NCT06197672·Phase 1·Recruiting·Listed Jan 2024

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Pediatric Cardiomyopathy Mutation Analysis

for Cardiomyopathies

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: All ages

Code: NCT02432092·Recruiting·Listed May 2015

Apply to this trial