Oncology Clinical Trials in Iowa City, IA

As of September 2026, 107 paid clinical trials are recruiting for Oncology in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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108 clinical trials for Oncology

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Iowa City, Des Moines +152 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Iowa City, Des Moines +141 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Collection of Tissue Samples for Cancer Research

for Neoplasms

Sites in Iowa City +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 Months+

Code: NCT00900198·Recruiting·Listed May 2009

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High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Iowa City

Sponsor: Kittika Poonsombudlert

Sex: All·Age: 18 - 75

Code: NCT07177079·Phase 1·Recruiting·Listed Sep 2025

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Iowa City +112 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

Sites in Iowa City +18 more locations

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting·Listed Jul 2022

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Breast Cancer PSMA PET

for Triple Negative Breast Cancer

1 location in Iowa City

Sponsor: Ahmad Shariftabrizi

Sex: Female·Age: 18 - 90

Code: NCT06586047·EARLY_Phase 1·Recruiting·Listed Sep 2024

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Ascorbate in Myelodysplastic Syndrome

for Myelodysplastic Syndromes

1 location in Iowa City

Sponsor: Prajwal Dhakal

Sex: All·Age: 18 - 99

Code: NCT07283900·Phase 2·Recruiting·Listed Dec 2025

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Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

for Chondrosarcoma

Sites in Iowa City +3 more locations

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT04040205·Phase 2·Recruiting·Listed Jul 2019

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

Sites in Iowa City +7 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2·Recruiting·Listed Dec 2018

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Iowa City, Cedar Rapids +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

for Breast Cancer

Sites in Iowa City +2 more locations

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT06169371·Phase 4·Recruiting·Listed Dec 2023

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Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

for Colon Cancer

Drug: Dostarlimab

Sites in Iowa City +1 more location

Sponsor: University of Iowa

Sex: All·Age: 18+

Code: NCT05239546·Phase 2·Recruiting·Listed Feb 2022

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Palbociclib and Pembrolizumab in Sarcoma

for Sarcoma

1 location in Iowa City

Sponsor: John Rieth

Sex: All·Age: 12+

Code: NCT06113809·Phase 1·Recruiting·Listed Nov 2023

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Iowa City +82 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Iowa City +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

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MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Monalizumab

Sites in Iowa City +3 more locations

Sponsor: Hirva Mamdani

Sex: All·Age: 18+

Code: NCT05903092·Phase 2·Recruiting·Listed Jun 2023

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Quantitative MRI Assessment of Breast Cancer Therapy Response

for Breast Cancer

Sites in Iowa City +2 more locations

Sponsor: Corewell Health East

Sex: All·Age: 18+

Code: NCT05704062·Recruiting·Listed Jan 2023

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

Sites in Iowa City +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

for Metastatic Melanoma

Drug: Dabrafenib

Sites in Iowa City +3 more locations

Sponsor: Rina Plattner

Sex: All·Age: 18+

Code: NCT04903119·Phase 1·Recruiting·Listed May 2021

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Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

Sites in Iowa City +16 more locations

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting·Listed Jan 2021

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Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma

for Cutaneous Melanoma

Drug: Avutometinib

Sites in Iowa City +1 more location

Sponsor: University of Utah

Sex: All·Age: 18+

Code: NCT06194929·Phase 1, Phase 2·Recruiting·Listed Jan 2024

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Sleep Apnea in Patients With MGUS and MM

for Multiple Myeloma

1 location in Iowa City

Sponsor: Michael Tomasson

Sex: All·Age: 18 - 99

Code: NCT04114084·Recruiting·Listed Oct 2019

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177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry

for Neuroendocrine Tumors

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18+

Code: NCT06395402·Phase 2·Recruiting·Listed May 2024

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Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer

for Bladder Cancer

Sites in Iowa City +1 more location

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18+

Code: NCT06493370·Phase 2·Recruiting·Listed Jul 2024

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Preop Laxatives in Robotic Urologic Surgery

for Prostate Cancer

1 location in Iowa City

Sponsor: Chad R. Tracy

Sex: All·Age: 30 - 100·Accepts healthy volunteers

Code: NCT05805436·Phase 4·Recruiting·Listed Apr 2023

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

Sites in Iowa City +9 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting·Listed Jul 2025

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Conditions in Oncology (Iowa City, IA)

Non-small cell lung cancer (NSCLC)· 14 Breast cancer· 13 Acute myeloid leukemia (AML)· 11 Non-Hodgkin lymphoma· 10 Solid tumor· 10 Multiple myeloma· 8 Hematologic malignancy· 7 Bladder cancer· 6 Leukemia (other)· 6 Myelodysplastic syndromes (MDS)· 6 Melanoma· 6 Metastatic breast cancer· 5 Ovarian cancer· 5 Diffuse large B-cell lymphoma (DLBCL)· 5 Cancer (any)· 5 Lung cancer· 4 Colorectal cancer· 4 Neuroendocrine tumors· 4 Triple-negative breast cancer· 3 HER2-negative breast cancer· 3 Pancreatic cancer· 3 Prostate cancer· 3 Endometrial cancer· 3 Cervical cancer· 3 Glioblastoma· 3 Chronic lymphocytic leukemia (CLL)· 3 Acute lymphoblastic leukemia· 3 Myeloproliferative neoplasm· 3 Follicular lymphoma· 3 Mantle cell lymphoma· 3 Small lymphocytic lymphoma· 3 Head and neck cancer· 3 Neuroblastoma· 3 Small cell lung cancer· 2 Colon cancer· 2 Gastric cancer· 2 Esophageal cancer· 2 Kidney cancer· 2 Marginal zone lymphoma· 2 Osteosarcoma· 2 Ewing sarcoma· 2 Pediatric cancer· 2 Gastroesophageal junction cancer· 1 Liver cancer· 1 Biliary tract cancer· 1 Metastatic prostate cancer· 1 Gynecologic cancer· 1 Glioma· 1 Brain metastases· 1 Myelofibrosis· 1 Hodgkin lymphoma· 1 Burkitt lymphoma· 1 Sarcoma· 1 Soft tissue sarcoma· 1