Paid Clinical Trials in Iowa City, IA

As of August 2026, 554 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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510 clinical trials

Empagliflozin Treatment in Kidney Transplant Recipients

for Kidney Transplant

Drug: Empagliflozin

Sites in Iowa City +4 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 19+

Code: NCT06013865·Phase 4·Recruiting·Listed Aug 2023

Apply to this trial

ATrial Tachycardia PAcing Therapy in Congenital Heart

for Atrial Arrhythmia

Sites in Iowa City +13 more locations

Sponsor: Ian Law

Sex: All·Age: All ages

Code: NCT03209583·Recruiting·Listed Jul 2017

Apply to this trial

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

Sites in Iowa City +22 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting·Listed Jul 2025

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Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

Sites in Iowa City +4 more locations

Sponsor: Dwight Owen

Sex: All·Age: 18+

Code: NCT04919382·Phase 2·Recruiting·Listed Jun 2021

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

Sites in Iowa City +72 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial

Quantitative MRI Assessment of Breast Cancer Therapy Response

for Breast Cancer

Sites in Iowa City +2 more locations

Sponsor: Corewell Health East

Sex: All·Age: 18+

Code: NCT05704062·Recruiting·Listed Jan 2023

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Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe

for Stroke, Acute

Sites in Iowa City +5 more locations

Sponsor: Santiago Ortega Gutierrez

Sex: All·Age: 18+

Code: NCT06825897·Recruiting·Listed Feb 2025

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MMP-9 Inhibition for Recalcitrant Wet AMD

for Exudative Macular Degeneration

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 50 - 99

Code: NCT04504123·Phase 2·Recruiting·Listed Aug 2020

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Iowa City +53 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Motor Outcomes to Validate Evaluations in Pediatric FSHD (MOVE Peds)

for Muscular Dystrophy, Facioscapulohumeral

Sites in Iowa City +5 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 5 - 17

Code: NCT06847282·Recruiting·Listed Feb 2025

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

Sites in Iowa City +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

Sites in Iowa City +57 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Iowa City +21 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

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Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

for Delirium

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 65+

Code: NCT05461092·EARLY_Phase 1·Recruiting·Listed Jul 2022

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JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

for Patellar Dislocation, Recurrent

Sites in Iowa City +15 more locations

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 10 - 35

Code: NCT06883396·Recruiting·Listed Mar 2025

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A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy

for Arthropathy of Knee

1 location in Iowa City

Sponsor: Nicolas Noiseux, MD, MS, FRCSC

Sex: All·Age: 18 - 100

Code: NCT04924205·Recruiting·Listed Jun 2021

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

Sites in Iowa City, Des Moines +292 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting·Listed Sep 2018

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Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

Sites in Iowa City +17 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting·Listed Feb 2025

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Cerebellar Stimulation and Cognitive Control

for Schizophrenia

1 location in Iowa City

Sponsor: Krystal Parker, PhD

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT03217110·Recruiting·Listed Jul 2017

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American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

Sites in Iowa City +29 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting·Listed Sep 2020

Apply to this trial

Concurrent TMS-fMRI

for Healthy Control

1 location in Iowa City

Sponsor: Jing Jiang

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06633913·Recruiting·Listed Oct 2024

Apply to this trial

The ED-AWARENESS-2 Trial

for Awareness

Sites in Iowa City +3 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05534243·Recruiting·Listed Sep 2022

Apply to this trial

Early Angiotensin II in the Emergency Department

for Septic Shock

1 location in Iowa City

Sponsor: Brett A Faine

Sex: All·Age: 18 - 99

Code: NCT06693726·Phase 4·Recruiting·Listed Nov 2024

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Ketorolac Use and Fresh Embryo Transfer Outcomes

for Infertility (IVF Patients)

1 location in Iowa City

Sponsor: Jessica D. Kresowik

Sex: Female·Age: 18 - 37

Code: NCT07185724·Phase 4·Recruiting·Listed Sep 2025

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

Sites in Iowa City +19 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting·Listed Aug 2025

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Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

for Metastatic Melanoma

Drug: Dabrafenib

Sites in Iowa City +3 more locations

Sponsor: Rina Plattner

Sex: All·Age: 18+

Code: NCT04903119·Phase 1·Recruiting·Listed May 2021

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Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

for Rotator Cuff Tears

Sites in Iowa City +3 more locations

Sponsor: University of Michigan

Sex: All·Age: 40 - 85

Code: NCT04831164·Recruiting·Listed Apr 2021

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Iowa City +67 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

Apply to this trial

Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

Sites in Iowa City +16 more locations

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting·Listed Jan 2021

Apply to this trial

Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe

for Ischemic Stroke

Sites in Iowa City +3 more locations

Sponsor: Raul Nogueira

Sex: All·Age: 18+

Code: NCT05983757·Recruiting·Listed Aug 2023

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

Sites in Iowa City, Des Moines +107 more locations

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting·Listed Apr 2025

Apply to this trial

University of Iowa Interventional Psychiatry Service Patient Registry

for Treatment Resistant Depression

1 location in Iowa City

Sponsor: Mark Niciu

Sex: All·Age: 18 - 99

Code: NCT04480918·Recruiting·Listed Jul 2020

Apply to this trial

Vascular Effects of High-Salt After Preeclampsia

for Preeclampsia

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06749418·EARLY_Phase 1·Recruiting·Listed Dec 2024

Apply to this trial

StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

Sites in Iowa City +40 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting·Listed Mar 2024

Apply to this trial

Real-time Personalized Brain State-dependent TMS After Stroke

for Stroke

1 location in Iowa City

Sponsor: Sara Hussain

Sex: All·Age: 18+

Code: NCT06533176·Recruiting·Listed Aug 2024

Apply to this trial

Pregnancy 24/7 Offspring Study

for Healthy

Sites in Iowa City +1 more location

Sponsor: Kara Whitaker

Sex: All·Age: 0 - 47·Accepts healthy volunteers

Code: NCT07172880·Recruiting·Listed Sep 2025

Apply to this trial

Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

Sites in Iowa City +39 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting·Listed Mar 2016

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Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for Prediabetic State

Sites in Iowa City +37 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02915198·Phase 4·Recruiting·Listed Sep 2016

Apply to this trial

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

Sites in Iowa City +40 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05338697·Recruiting·Listed Apr 2022

Apply to this trial

Cell Free DNA in Cardiac Sarcoidosis

for Sarcoidosis With Myocarditis

2 locations in Iowa City

Sponsor: Nabeel Hamzeh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03858777·Recruiting·Listed Mar 2019

Apply to this trial