Paid Clinical Trials in Iowa City, IA

As of August 2026, 554 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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Healthy volunteers only

510 clinical trials

Paced Heart Rate Acceleration for Cardiac Conditioning

for Heart Failure, Systolic

1 location in Iowa City

Sponsor: Denice Hodgson-Zingman, MD

Sex: All·Age: 18 - 120

Code: NCT06332391·Recruiting·Listed Mar 2024

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Iowa City +86 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Carbon Dioxide (CO2) Chemosensitivity and SUDEP

for Epilepsy

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 99

Code: NCT04134754·Recruiting·Listed Oct 2019

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PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department

for Supraventricular Tachycardia (SVT)

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 100

Code: NCT07086560·Recruiting·Listed Jul 2025

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Iowa City +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

for Breast Neoplasm Female

Sites in Iowa City +1 more location

Sponsor: University of Wisconsin, Madison

Sex: Female·Age: 18+

Code: NCT03096418·Phase 4·Recruiting·Listed Mar 2017

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Harnessing Communication Preferences

for Intellectual Disability

Sites in Iowa City +1 more location

Sponsor: Joel E. Ringdahl

Sex: All·Age: 2 - 90

Code: NCT07278544·Recruiting·Listed Dec 2025

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Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

for Colon Cancer

Drug: Dostarlimab

Sites in Iowa City +1 more location

Sponsor: University of Iowa

Sex: All·Age: 18+

Code: NCT05239546·Phase 2·Recruiting·Listed Feb 2022

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Iowa City, Des Moines +161 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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Aquagenic Wrinkling Prediction

for Aquagenic Wrinkling of Palms

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT06831110·Recruiting·Listed Feb 2025

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Adenosine vs Diltiazem for Treatment of SVT in the ED

for Supraventricular Tachycardia (SVT)

1 location in Iowa City

Sponsor: Anne E. Zepeski

Sex: All·Age: 18 - 100

Code: NCT06993038·Phase 4·Recruiting·Listed May 2025

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Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

Sites in Iowa City +51 more locations

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting·Listed Apr 2025

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Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

Sites in Iowa City +12 more locations

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting·Listed Jan 2024

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Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

for Giant Cell Tumor of Bone

Sites in Iowa City +10 more locations

Sponsor: St. Louis University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03295981·Phase 3·Recruiting·Listed Sep 2017

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Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

for FSHD

Sites in Iowa City +15 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: All ages

Code: NCT04635891·Recruiting·Listed Nov 2020

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High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Iowa City

Sponsor: Kittika Poonsombudlert

Sex: All·Age: 18 - 75

Code: NCT07177079·Phase 1·Recruiting·Listed Sep 2025

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Palbociclib and Pembrolizumab in Sarcoma

for Sarcoma

1 location in Iowa City

Sponsor: John Rieth

Sex: All·Age: 12+

Code: NCT06113809·Phase 1·Recruiting·Listed Nov 2023

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Aerodynamic Measurements in the Pediatric Population

for Normal Voice

Sites in Iowa City +1 more location

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 4 - 65·Accepts healthy volunteers

Code: NCT06975046·Recruiting·Listed May 2025

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Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

Sites in Iowa City +12 more locations

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting·Listed Mar 2020

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Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

for LAMA2-MD \(Merosin Deficient Congenital Muscular Dystrophy, MDC1A\)

Sites in Iowa City +13 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 5

Code: NCT06503367·Recruiting·Listed Jul 2024

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

Sites in Iowa City +35 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting·Listed May 2022

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Cochlear Implant Speech in Noise Processing

for Hearing Loss, Adult-Onset

1 location in Iowa City

Sponsor: Craig D. Workman, PhD

Sex: All·Age: 18 - 99

Code: NCT06860152·Recruiting·Listed Mar 2025

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

Sites in Iowa City +40 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting·Listed Oct 2019

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Hyperbaric Oxygen Brain Injury Treatment Trial

for Traumatic Brain Injury

Sites in Iowa City +7 more locations

Sponsor: Gaylan Rockswold

Sex: All·Age: 16 - 65

Code: NCT02407028·Phase 2·Recruiting·Listed Apr 2015

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Iowa City, Cedar Rapids +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

Sites in Iowa City +22 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting·Listed Jun 2024

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Iowa City +27 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023

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Neonatal Platelet Transfusion Threshold Trial

for Thrombocytopenia

Sites in Iowa City +19 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 1 Hour - 48 Hours·Accepts healthy volunteers

Code: NCT06676904·Recruiting·Listed Nov 2024

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Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility

for Schizophrenia

1 location in Iowa City

Sponsor: Kai Hwang

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07217652·Recruiting·Listed Oct 2025

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Iowa City, Des Moines +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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IH, Brain Health, and T2D

for Type 2 Diabetes

1 location in Iowa City

Sponsor: Darren P Casey

Sex: All·Age: 60 - 85·Accepts healthy volunteers

Code: NCT07173543·Recruiting·Listed Sep 2025

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Ketamine Alcohol (in Treatment-Resistant Depression)

for Magnetic Resonance Imaging

1 location in Iowa City

Sponsor: Mark Niciu

Sex: All·Age: 18 - 55

Code: NCT02122562·Phase 2·Recruiting·Listed Apr 2014

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Hyperpolarized 129Xe MRI Lung Health Cohort

for Healthy

Sites in Iowa City +5 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 25 - 35

Code: NCT05766384·Recruiting·Listed Mar 2023

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Iowa City +82 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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Generic Database of Very Low Birth Weight Infants

for Infant, Newborn

Sites in Iowa City +14 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 14 Days

Code: NCT00063063·Recruiting·Listed Jun 2003

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MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Monalizumab

Sites in Iowa City +3 more locations

Sponsor: Hirva Mamdani

Sex: All·Age: 18+

Code: NCT05903092·Phase 2·Recruiting·Listed Jun 2023

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Genetic Risk Factor for Heat Stroke

for Carrier State

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 60

Code: NCT06847256·Recruiting·Listed Feb 2025

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IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

for Laparotomy

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 85

Code: NCT06559969·Phase 2, Phase 3·Recruiting·Listed Aug 2024

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Sinus Disease in Young Children With Cystic Fibrosis

for Cystic Fibrosis in Children

Sites in Iowa City +5 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 2 - 8

Code: NCT06191640·Recruiting·Listed Jan 2024

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Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer

for Merkel Cell Carcinoma

Sites in Iowa City +2 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT05583708·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial