Hidradenitis suppurativa Clinical Trials in Knoxville, TN
As of June 2026, 1 paid clinical trial is recruiting for Hidradenitis suppurativa in Knoxville, Tennessee. Recruiting Hidradenitis suppurativa studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for Hidradenitis suppurativa
·Clear filters·↓ Download CSVAbout research studies in Knoxville
Knoxville has approximately 229 recruiting research studies across a wide range of therapeutic areas. Tennessee is home to Vanderbilt University Medical Center and St. Jude Children's Research Hospital — world leaders in pediatric oncology and personalized medicine.
Top Research Study Locations in Knoxville
Researchers run research studies in Knoxville, TN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Tennessee Medical Center | Carcinoma, Non-Small-Cell Lung, Hepatocellular Carcinoma, AD | 26 |
| East Tennessee Childrens Hospital | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Down Syndrome | 23 |
| University of Tennessee - Knoxville | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 17 |
| Tennessee Cancer Specialists | Breast Cancer, Advanced Breast Cancer, Carcinoma, Non-Small-Cell Lung | 8 |
| University of Tennessee | AI-Based Fitness, Advanced Melanoma, Carcinoma, Non-Small-Cell Lung | 7 |
| University of Tennessee Graduate School of Medicine | Cardiac Amyloidosis, Cardiometabolic Diseases, Carpal Tunnel Syndrome (CTS) | 6 |
| Southeastern Retina Associates, P.C. | Diabetic Retinopathy, Geographic Atrophy, Macular Degeneration | 4 |
| The University of Tennessee Medical Center | Coronary Artery Disease, Hernia, Ventral, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer | 4 |
| Thompson Proton Center | Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II | 4 |
| Alliance for Multispecialty Research, LLC | ALS, Healthy Participants, Menstrual Migraine | 3 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, Generalized Myasthenia Gravis | 3 |
| AMR Clinical | Focus of the Study: Safety of XFB19, Menstrual Migraine, Osteoarthritis | 3 |
| Covenant Health Cancer Centers | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Clinical Stage I Esophageal Adenocarcinoma AJCC v8 | 3 |
| Covenant Health Cancer Centers - West | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Clinical Stage I Esophageal Adenocarcinoma AJCC v8 | 3 |
| Hope Neurology | Multiple Sclerosis, Multiple Sclerosis Spasticity, Relapsing-remitting Multiple Sclerosis (RRMS) | 3 |
| New Phase Research and Development | Obesity, Overweight, Chronic Low Back Pain (CLBP) | 3 |
| Parkwest Medical Center | AMI Cardiogenic Shock, Aortic Stenosis, Aortic Stenosis, Calcific | 3 |
| Tennova Healthcare - Turkey Creek Medical Center | Heart Failure, Atrial Fibrillation, Stroke | 3 |
| Fort Sanders Regional Medical Center | Alzheimer Dementia, Alzheimer Disease, Atrial Fibrillation | 2 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Pulmonary Disease, Chronic Obstructive | 2 |
| Genesis Neuroscience Clinic | Alzheimers Disease | 2 |
| Healthy Eating and Activity Laboratory | Obesity, Childhood Obesity | 2 |
| Kailera Clinical Site | Obesity, Overweight | 2 |
| Knoxville Kidney Center, PLLC | Immunoglobulin A Nephropathy (IgAN), Primary Membranous Nephropathy | 2 |
| MBX Biosciences Investigational Site | Obesity, Postbariatric Hypoglycemia | 2 |
Active & Upcoming Studies in Knoxville (2026)
Recruiting trials in Knoxville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (94 active studies)
- DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy · Phase 3 · Boehringer Ingelheim
- Testing the SurVaxM Vaccine for Lung Cancer Prevention · Phase 2 · National Cancer Institute (NCI)
Cardiovascular (21 active studies)
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Neurology & pain (17 active studies)
- Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis · Phase 3 · Sanofi
- Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy · Phase 3 · Vertex Pharmaceuticals Incorporated
Diabetes & metabolic (14 active studies)
- Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity · Phase 2 · Kailera
- Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes · Phase 2 · Kailera
Eye & vision (4 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO · Phase 2 · EyeBiotech Ltd.
Mental health & behavior (2 active studies)
- Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability · Phase 1 · JT International SA
- Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence · University of Tennessee
Vaccines (1 active study)
- Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults · Phase 1 · Clover Biopharmaceuticals USA, LLC
Pediatric (1 active study)
- Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy · Massachusetts General Hospital
Common conditions studied in Knoxville
- Obesity (8 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Breast Cancer (6 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Myeloid Leukemia (5 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Carcinoma, Non-Small-Cell Lung (5 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Hypertension (5 active studies). Hypertension research tests new antihypertensive drug classes, renal denervation devices, and fixed-dose combinations for resistant disease.
- Heart Failure (4 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
Leading research sponsors in Knoxville
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
- Merck Sharp & Dohme LLC
- University of Tennessee Graduate School of Medicine
Local regulations and guidelines
Clinical trials in Tennessee are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Tennessee research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Knoxville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Knoxville
Hipa.ai aggregates every recruiting study in Knoxville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Knoxville?
There are approximately 229 recruiting clinical trials in Knoxville, Tennessee listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Knoxville pay participants?
Most recruiting trials in Knoxville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Knoxville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Knoxville?
The most common conditions under active study in Knoxville include Obesity (8), Breast Cancer (6), Acute Myeloid Leukemia (5), Carcinoma, Non-Small-Cell Lung (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Knoxville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Knoxville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Knoxville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Knoxville?
Recruiting research sites in Knoxville include University of Tennessee Medical Center, East Tennessee Childrens Hospital, University of Tennessee - Knoxville, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Knoxville right now?
The largest active categories in Knoxville are Cancer & tumors (94), Cardiovascular (21), Neurology & pain (17). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.