Paid Clinical Trials in Kentucky

Kentucky has 961 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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871 clinical trials

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Louisville, Lexington +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

Apply to this trial

Bromelain for Post-surgery Facial Swelling

for Malocclusion

1 location in Lexington

Sponsor: Mohamed Bazina

Sex: All·Age: 18 - 65

Code: NCT07115212·Recruiting·Listed Aug 2025

Apply to this trial

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Lexington, Bardstown +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

for Extubation Failure

Sites in Louisville +15 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 9 Weeks

Code: NCT05446272·Recruiting·Listed Jul 2022

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Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity

for Obesity and Overweight

1 location in Lexington

Sponsor: John Bauer

Sex: All·Age: 12 - 17

Code: NCT06967389·Recruiting·Listed May 2025

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in Lexington +26 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Louisville, Lexington +471 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

Apply to this trial

The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

Sites in Lexington +6 more locations

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting·Listed Apr 2021

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Louisville, Lexington +209 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

Cocaine and Pentoxifylline (BED IN 47)

for Cocaine Use Disorder

1 location in Lexington

Sponsor: William Stoops

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07086794·EARLY_Phase 1·Recruiting·Listed Jul 2025

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in Lexington +29 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

Sites in Lexington +13 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting·Listed Jun 2022

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

Sites in Lexington +145 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting·Listed May 2024

Apply to this trial

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

Sites in Louisville +32 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

Apply to this trial

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Louisville, Lexington +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

Apply to this trial

Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability

for Ankle Sprains

Sites in Lexington +1 more location

Sponsor: Danielle Torp

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06868316·Recruiting·Listed Mar 2025

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Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery

for Diabetes Mellitus, Type 1

Sites in Louisville +2 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18 - 65

Code: NCT06880835·Recruiting·Listed Mar 2025

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Hypofractionated Radiochemotherapy

for Uterine Cervix Cancer

1 location in Lexington

Sponsor: Denise Fabian

Sex: Female·Age: 18 - 120

Code: NCT06331468·Phase 2·Recruiting·Listed Mar 2024

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Louisville +16 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

Sites in Lexington +40 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019

Apply to this trial

Impact of Daily Oral Cannabis Doses in Patients With Cancer

for Cancer

1 location in Lexington

Sponsor: Shanna Babalonis, PhD

Sex: All·Age: 18+

Code: NCT06601218·Phase 1·Recruiting·Listed Sep 2024

Apply to this trial

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

for Quality of Life

Sites in Lexington +3 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06856057·Recruiting·Listed Mar 2025

Apply to this trial

Pembro With Radiation With or Without Olaparib

for Prostate Cancer

Drug: Olaparib

1 location in Lexington

Sponsor: Zin W Myint

Sex: Male·Age: 18+

Code: NCT05568550·Phase 2·Recruiting·Listed Oct 2022

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Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

for Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation

Sites in Lexington +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05691465·Phase 2·Recruiting·Listed Jan 2023

Apply to this trial

A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL)

for Diffuse Large B Cell Lymphoma Refractory

1 location in Lexington

Sponsor: Pierluigi Porcu

Sex: All·Age: 18+

Code: NCT06789159·Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

for Heart Failure

Drug: Finerenone

Sites in Louisville, Lexington +52 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06033950·Phase 3·Recruiting·Listed Sep 2023

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Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study

for Spinal Cord Stimulation

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18 - 80

Code: NCT06520020·Recruiting·Listed Jul 2024

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Louisville, Lexington +78 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

Apply to this trial

Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment

for Mild Cognitive Impairment

1 location in Lexington

Sponsor: Julie Pendergast

Sex: Female·Age: 45 - 95

Code: NCT05858008·Recruiting·Listed May 2023

Apply to this trial

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

Sites in Louisville +11 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting·Listed Mar 2025

Apply to this trial

IOA Preventing Occlusal Changes With MAD Use

for Sleep Related Breathing Disorder

1 location in Lexington

Sponsor: Isabel Moreno Hay

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07103941·Recruiting·Listed Aug 2025

Apply to this trial

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Lexington, Corbin +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Muscle Recovery After Critical Illness

for ICU Acquired Weakness

1 location in Lexington

Sponsor: Esther Dupont-Versteegden

Sex: Male·Age: 18+

Code: NCT05537298·Recruiting·Listed Sep 2022

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Louisville, Lexington +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Louisville +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

Apply to this trial

Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

Sites in Lexington +32 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting·Listed Dec 2022

Apply to this trial

Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

Sites in Lexington +17 more locations

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting·Listed Nov 2019

Apply to this trial

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

Sites in Louisville, Lexington +20 more locations

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting·Listed Feb 2022

Apply to this trial

Methamphetamine and Troriluzole

for Methamphetamine Use Disorder

1 location in Lexington

Sponsor: William Stoops

Sex: All·Age: 18 - 55

Code: NCT06989853·EARLY_Phase 1·Recruiting·Listed May 2025

Apply to this trial

Comprehensive Connected Cancer Care (C4): Intervention Evaluation

for Cancer

1 location in Lexington

Sponsor: Timothy Mullett

Sex: All·Age: 18+

Code: NCT06326567·Recruiting·Listed Mar 2024

Apply to this trial