A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

Part of paid clinical trials in Fairhope, Alabama.

Sponsor: Colorado Prevention Center
Study ID: NCT06033950
Phase: PHASE3
Status: Recruiting

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Conditions

Heart Failure

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

Finerenone — DRUG
Oral finerenone.
Placebo — DRUG
Matching oral placebo.

Study Details

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HFrEF) who are intolerant or ineligible to receive treatment with steroidal mineralocorticoid receptor antagonists (sMRA).

Key Dates

First listed: Sep 13, 2023
Start date: Aug 20, 2024
Status verified: Jul 2026
Primary completion: Aug 31, 2026
Completion: Jan 31, 2028

Study Design

Enrollment: 2,600 participants (estimated)
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Arms

Experimental: Finerenone
Placebo Comparator: Placebo

Primary Outcome Measure

Time to first occurrence of cardiovascular (CV) death or HF event. [ Time Frame: Ongoing, up to ~30 months ]

Central Contacts

Marc Bonaca
(303) 860-9900
[email protected]

Locations (54)

Facility	City	State	ZIP	Site coordinators
FIN-10004 Fairhope, AL Investigational Site	Fairhope	Alabama	36532	Bonaca, MD [email protected] +1-303-860-9900
Phoenix, AZ Investigative Site FIN-10115	Phoenix	Arizona	85006	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10401, Yuma, AZ	Yuma	Arizona	85365	Bonaca, MD [email protected] +1-303-860-9900
Chula Vista, CA Investigative Site FIN-10111	Chula Vista	California	91911	Marc Bonaca, MD [email protected] +1-303-860-9900
Chula Vista, CA Investigative Site FIN-10419	Chula Vista	California	91910	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10407, Northridge, CA	Northridge	California	91324	Bonaca, MD [email protected] +1-303-860-9900
FIN-10412, Orange, CA	Orange	California	92866	Bonaca, MD [email protected] +1-303-860-9900
FIN-10070, Pamona, CA	Pomona	California	91767	Bonaca, MD [email protected] +1-303-860-9900
FIN-10024, Sacramento, CA	Sacramento	California	95816	Bonaca, MD [email protected] +1-303-860-9900
FIN-10075 San Diego, CA Investigational Site	San Diego	California	92243	Bonaca, MD [email protected] +1-303-860-9900
FIN-10406, San Diego, CA	San Diego	California	91127	Bonaca, MD [email protected] +1-303-860-9900
San Diego, CA Investigative Site FIN-10420	San Diego	California	92111	Marc Bonaca, MD [email protected] +1-303-860-9900
San Francisco, CA Investigative Site FIN-10023	San Francisco	California	94118	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10423, Sherman Oaks, CA	Sherman Oaks	California	91403	Bonaca, MD [email protected] +1-303-860-9900
FON-10409, Tarzana, CA	Tarzana	California	91356	Bonaca, MD [email protected] +1-303-860-9900
FIN-10109, Van Nuys, CA	Van Nuys	California	91405	Bonaca, MD [email protected] +1-303-860-9900
FIN-10408, West Covina, CA	West Covina	California	91790	Bonaca, MD [email protected] +1-303-860-9900
FIN-10013, West Hills, CA	West Hills	California	91307	Bonaca, MD [email protected] +1-303-860-9900
FIN-10001, Aurora, CO	Aurora	Colorado	80045	Bonaca, MD [email protected] +1-303-860-9900
FIN-10110, Aurora, CO	Aurora	Colorado	80012	Bonaca, MD [email protected] +1-303-860-9900
Bradenton, FL Investigative Site FIN-10125	Bradenton	Florida	34209	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10104, Hialeah, FL	Hialeah	Florida	33012	Bonaca, MD [email protected] +1-303-860-9900
FIN-10028, Jacksonville, FL	Jacksonville	Florida	32209	Bonaca, MD [email protected] +1-303-860-9900
FIN-10105, Miami, FL	Miami	Florida	33135	Bonaca, MD [email protected] +1-303-860-9900
FIN-10113, Miramar, FL	Miramar	Florida	33027	Bonaca, MD [email protected] +1-303-860-9900
FIN-10019, Peoria, IL	Peoria	Illinois	61603	Bonaca, MD [email protected] +1-303-860-9900
FIN-10064, Merrillville, IN	Merrillville	Indiana	46410	Bonaca, MD [email protected] +1-303-860-9900
Cynthiana, KY Investigative Site FIN-10124	Cynthiana	Kentucky	41031	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10080, Lexington, KY	Lexington	Kentucky	40503	Bonaca, MD [email protected] +1-303-860-9900
Lexington, KY Investigative Site FIN-10118	Lexington	Kentucky	40536	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10086, Louisville, KY	Louisville	Kentucky	40205	Bonaca, MD [email protected] +1-303-860-9900
Louisville, KY Investigative Site FIN-10417	Louisville	Kentucky	40205	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10079, Paducah, KY	Paducah	Kentucky	42003	Bonaca, MD [email protected] +1-303-860-9900
FIN-10030, Baton Rouge, LA	Baton Rouge	Louisiana	70808	Bonaca, MD [email protected] +1-303-860-9900
FIN-10106, Hammond, LA	Hammond	Louisiana	70403	Bonaca, MD [email protected] +1-303-860-9900
FIN-10090, West Monroe, LA	West Monroe	Louisiana	71291	Bonaca, MD [email protected] +1-303-860-9900
Minneapolis, MN Investigative Site FIN-10035	Minneapolis	Minnesota	55417	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10002 Kansas City, MO Investigational Site	Kansas City	Missouri	64111	Bonaca [email protected] +1-303-860-9900
FIN-10318, Charlotte, NC	Charlotte	North Carolina	28207	Bonaca, MD [email protected] +1-303-860-9900
Greenville, NC Investigative Site FIN-10122	Greenville	North Carolina	27834	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10081, Akron, OH	Akron	Ohio	44304	Bonaca, MD [email protected] +1-303-860-9900
FIN-10119, Centerville, OH	Centerville	Ohio	45459	Bonaca, MD [email protected] +1-303-860-9900
FIN- 10112, Cincinnati, OH	Cincinnati	Ohio	45219	Bonaca, MD [email protected] +1-303-860-9900
Orangeburg, SC Investigative Site FIN-10433	Orangeburg	South Carolina	29118	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10015 Austin, TX Investigational Site	Austin	Texas	78705	Bonaca [email protected] +1-303-860-9900
FIN-10404, Denison, TX	Denison	Texas	75020	Bonaca, MD [email protected] +1-303-860-9900
FIN-10085, Houston, TX	Houston	Texas	77030	Bonaca, MD [email protected] +1-303-860-9900
Tyler, TX Investigative Site FIN-10422	Tyler	Texas	75702	Marc Bonaca, MD [email protected] +1-303-860-9900
FIN-10405, Layton, UT	Layton	Utah	84041	Bonaca, MD [email protected] +1-303-860-9900
FIN-10053, Burlington, VT	Burlington	Vermont	05401	Bonaca, MD [email protected] +1-303-860-9900
FIN-10402, Norfolk, VA	Norfolk	Virginia	23510	Bonaca, MD [email protected] +1-303-860-9900
FIN-10093, Richmond, VA	Richmond	Virginia	23298-5051	Bonaca, MD [email protected] +1-303-860-9900
Salem, VA Investigative Site FIN-10048	Salem	Virginia	24153	Marc Bonaca, MD [email protected] +1-303-860-9900
Milwaukee, WI Investigative Site FIN-10428	Milwaukee	Wisconsin	53215	Marc Bonaca, MD [email protected] +1-303-860-9900

Find similar trials in Fairhope, AL

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By condition

Heart failure

By specialty

Cardiology Heart disease

By research site

FIN-10004 Fairhope, AL Investigational Site· Fairhope, AL Phoenix, AZ Investigative· Phoenix, AZ FIN-10401, Yuma, AZ· Yuma, AZ Chula Vista, CA Investigative· Chula Vista, CA FIN-10407, Northridge, CA· Northridge, CA FIN-10412, Orange, CA· Orange, CA

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