Clinical Trials at University of Kentucky

As of August 2026, 103 paid clinical trials are recruiting at University of Kentucky, located at University of Kentucky Research Foundation, Kinkead Hall, 201 Kinkead Hall, Lexington, KY 40508, phone (859) 257-8311 in Lexington, Kentucky. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

105 clinical trials at University of Kentucky

·Clear filters·

Pembro With Radiation With or Without Olaparib

for Prostate Cancer

1 location in Lexington

Sponsor: Zin W Myint

Sex: Male·Age: 18+

Code: NCT05568550·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

Sites in Lexington +13 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting·Listed Jun 2022

Apply to this trial

A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL)

for Diffuse Large B Cell Lymphoma Refractory

1 location in Lexington

Sponsor: Pierluigi Porcu

Sex: All·Age: 18+

Code: NCT06789159·Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment

for Mild Cognitive Impairment

1 location in Lexington

Sponsor: Julie Pendergast

Sex: Female·Age: 45 - 95

Code: NCT05858008·Recruiting·Listed May 2023

Apply to this trial

Muscle Recovery After Critical Illness

for ICU Acquired Weakness

1 location in Lexington

Sponsor: Esther Dupont-Versteegden

Sex: Male·Age: 18+

Code: NCT05537298·Recruiting·Listed Sep 2022

Apply to this trial

Comprehensive Connected Cancer Care (C4): Intervention Evaluation

for Cancer

1 location in Lexington

Sponsor: Timothy Mullett

Sex: All·Age: 18+

Code: NCT06326567·Recruiting·Listed Mar 2024

Apply to this trial

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

Sites in Lexington, Louisville +20 more locations

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting·Listed Feb 2022

Apply to this trial

K23- Physical Self Regulation vs Placebo

for Temporomandibular Disorder

1 location in Lexington

Sponsor: Ian Boggero, PhD

Sex: All·Age: 18+

Code: NCT06357702·Recruiting·Listed Apr 2024

Apply to this trial

Intramedullary Calcium Sulfate Antibiotic Depot

for Open tíbia Fracture

Sites in Lexington +9 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05766670·Phase 3·Recruiting·Listed Mar 2023

Apply to this trial

Loupe-Based Intraoperative Fluorescence Imaging

for Glioblastoma Multiforme

1 location in Lexington

Sponsor: Guoqiang Yu

Sex: All·Age: 18 - 90

Code: NCT04780009·Recruiting·Listed Mar 2021

Apply to this trial

REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19

for COVID-19

Sites in Lexington +4 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05218083·Recruiting·Listed Feb 2022

Apply to this trial

Mechanisms for Activation of Beige Adipose Tissue in Humans

for PreDiabetes

1 location in Lexington

Sponsor: Philip Kern

Sex: All·Age: 35 - 65·Accepts healthy volunteers

Code: NCT04666636·Phase 2·Recruiting·Listed Dec 2020

Apply to this trial

Leveraging Community-clinical Linkages to Address Unmet Social Needs for People With Diabetes

for Diabetes

1 location in Lexington

Sponsor: Mary Lacy

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07196007·Recruiting·Listed Sep 2025

Apply to this trial

Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

Sites in Lexington +25 more locations

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting·Listed Jul 2022

Apply to this trial

Opioid Drug Interaction Study

for Drug Interactions

1 location in Lexington

Sponsor: Shanna Babalonis, PhD

Sex: All·Age: 18 - 55

Code: NCT06757140·Phase 1, Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

2024 Tirzepatide-Bariatric Surgery

for Obesity and Obesity-related Medical Conditions

Drug: Tirzepatide

1 location in Lexington

Sponsor: Marlene Starr

Sex: All·Age: 18+

Code: NCT06721507·Phase 4·Recruiting·Listed Dec 2024

Apply to this trial

Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)

for Chronic Ankle Instability

Sites in Lexington +1 more location

Sponsor: Womack Army Medical Center

Sex: All·Age: 18 - 44

Code: NCT06527287·Recruiting·Listed Jul 2024

Apply to this trial

Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment

for Lung Cancer

1 location in Lexington

Sponsor: Laurie McLouth

Sex: All·Age: 18+

Code: NCT06047301·Recruiting·Listed Sep 2023

Apply to this trial

School Screening and Telemedicine Specialty Referral to Address Childhood Hearing Loss in Rural Kentucky

for Hearing Loss

1 location in Lexington

Sponsor: University of Arkansas

Sex: All·Age: 3 - 11·Accepts healthy volunteers

Code: NCT05513833·Recruiting·Listed Aug 2022

Apply to this trial

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

Sites in Lexington +20 more locations

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting·Listed Mar 2025

Apply to this trial

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

for Colorectal Cancer Metastatic

1 location in Lexington

Sponsor: Michael J Cavnar, MD

Sex: All·Age: 18 - 99

Code: NCT07201519·Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

for Peritoneal Carcinomatosis

Sites in Lexington +1 more location

Sponsor: Prakash Pandalai

Sex: All·Age: 18+

Code: NCT04779554·Phase 2·Recruiting·Listed Mar 2021

Apply to this trial

Home-based Under Mattress Monitor for OSA

for Obstructive Sleep Apnea (OSAS)

1 location in Lexington

Sponsor: Isabel Moreno Hay

Sex: All·Age: 18 - 80

Code: NCT07186725·Recruiting·Listed Sep 2025

Apply to this trial

Restoration of Hypoglycemia Awareness With Metoclopramide

for Hypoglycemia Unawareness

1 location in Lexington

Sponsor: Simon Fisher

Sex: All·Age: 20 - 60

Code: NCT03970720·Phase 2·Recruiting·Listed May 2019

Apply to this trial

InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery

for Fracture of Hip

1 location in Lexington

Sponsor: Paul E. Matuszewski

Sex: All·Age: 55+

Code: NCT06024304·Recruiting·Listed Sep 2023

Apply to this trial

Tasting Plant Forward Meals

for Dietary Exposure

1 location in Lexington

Sponsor: Sara Maksi

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT07202988·Recruiting·Listed Oct 2025

Apply to this trial

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

for Multiple System Atrophy

1 location in Lexington

Sponsor: Craig van Horne, MD, PhD

Sex: All·Age: 40 - 75

Code: NCT06683365·Phase 1·Recruiting·Listed Nov 2024

Apply to this trial

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

for Aortic Aneurysm

Sites in Lexington +13 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04005976·Recruiting·Listed Jul 2019

Apply to this trial

Closed Loop and Education for Hypoglycemia Awareness Restoration

for Diabetes Mellitus, Type 1

Sites in Lexington +4 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06325202·Recruiting·Listed Mar 2024

Apply to this trial

Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture

for Ankle Fractures

1 location in Lexington

Sponsor: Brian W. Noehren

Sex: All·Age: 18 - 50

Code: NCT07173088·Recruiting·Listed Sep 2025

Apply to this trial

Losartan to Improve Outcomes After Multi-ligament Knee Injury

for Multi-ligament Knee Injury

Sites in Lexington +2 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 40

Code: NCT06933706·Phase 2·Recruiting·Listed Apr 2025

Apply to this trial

Spinal Cord Injury Neuroprotection With Glyburide

for Acute Spinal Cord Injury

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05426681·Phase 1·Recruiting·Listed Jun 2022

Apply to this trial

Degenerative Cervical Myelopathy Repository

for Cervical Myelopathy

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18 - 100

Code: NCT05446259·Recruiting·Listed Jul 2022

Apply to this trial

Prospective Analysis of Spinal Epidural Abscess

for Spinal Epidural Abscess

1 location in Lexington

Sponsor: Francis Farhadi

Sex: All·Age: 18+

Code: NCT05464251·Recruiting·Listed Jul 2022

Apply to this trial

The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

for Pre-diabetes

1 location in Lexington

Sponsor: Philip Kern

Sex: All·Age: 35 - 65·Accepts healthy volunteers

Code: NCT05051436·Phase 4·Recruiting·Listed Sep 2021

Apply to this trial

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Lexington +67 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

Apply to this trial

Biopsy Collection and Repository Database

for Cardiovascular Diseases

1 location in Lexington

Sponsor: Kenneth S. Campbell

Sex: All·Age: 18+

Code: NCT05521503·Recruiting·Listed Aug 2022

Apply to this trial

Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing

for Wound Healing

1 location in Lexington

Sponsor: Janice Hernandez, MD

Sex: All·Age: 18 - 100

Code: NCT07075159·Recruiting·Listed Jul 2025

Apply to this trial

Abatacept in Immune Checkpoint Inhibitor Myocarditis

for Myocarditis Acute

Sites in Lexington +28 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05335928·Phase 3·Recruiting·Listed Apr 2022

Apply to this trial

Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients

for Heart Failure

1 location in Lexington

Sponsor: Maya Ignaszewski

Sex: All·Age: 18+

Code: NCT05537467·Recruiting·Listed Sep 2022

Apply to this trial